Oral Carcinogenesis
Mostrando 13-24 de 38 artigos, teses e dissertações.
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13. Análise da expressão de receptores hormonais (androgênio, estrogênio alfa e beta) e da aromatase em carcinomas epidermóides de boca (CE) / Analysis of the expression of hormonal receptors (androgen, estrogen alpha and beta) and aromatase enzime in oral squamous cell carcinoma (OSCC)
Das diversas neoplasias denominadas câncer de boca, mais de 95% tem o diagnóstico de carcinoma epidermóide (CE). O carcinoma epidermóide apresenta etiologia e patogênese complexas e não totalmente compreendidas determinando altos índices de morbidade e mortalidade. Por isso crescentes esforços têm sido empregados para a melhor compreensão dos event
Publicado em: 2010
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14. Leucoplasia oral: tratamento cirúrgico com laser de CO2 e de diodo e análise por imuno-histoquímica da expressão de proteínas relacionadas à carcinogênese (p53, COX-2 e EGFR) / Oral leukoplakia: surgical treatment with CO2 and diode lasers and analysis of the expression of proteins related to carcinogenesis (p53, COX-2 e EGFR) by immunohistochemistry
Oral leukoplakia (OL) is a potentially malignant lesion, defined as a white patch that cannot be characterized as any other disease of the oral mucosa. In general, OL should be treated; however no treatment available has been able to prevent malignant transformation. The aim of this study was to evaluate the efficacy of surgical treatment with CO2 and diode
Publicado em: 2010
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15. Comparação imunoistoquímica das expressões das proteínas p27 e c-jun na carcinogênese intra-oral / Immunohistochemical comparison between the p27 and c-jun proteins expression in the oral carcinogenesis
The expression of many cell cycle proteins has been studied in a number of malignant lesions. Among the main ones is the p27, which is encoded by the same name tumor suppressor gene, and it is altered in carcinomas, including oral cancers. Another protein that plays a role in the cell cycle control is the c-jun, which is encoded by a proto-oncogene, and acts
Publicado em: 2009
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16. AvaliaÃÃo da aÃÃo da laserterapia nÃo cirÃrgica em modelo experimental induzido por cacinÃgeno quÃmico
Low energy laser promotes therapeutic effects and morfodifferentiation and cell proliferation alterations. Its action in the proliferative activity is a controversial subject because studies show inhibition, proliferation or indifference regarding the cellular growth. In fact, the proliferation of normal and tumoral cells can be stimulated, but this process
Publicado em: 2009
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17. Analysis of NF-kappaB protein expression before and after treatment with Dexamethasone and oils Copaiba and Andiroba in cell lineage of Oral Squamous Cell Carcinoma / Análise da expressão da proteína NF-KappaB antes e depois do tratamento com Dexametasona e os óleos de Copaíba e Andiroba em cultura de células de Carcinoma Epidermóide Bucal
O carcinoma epidermóide (CE) representa mais de 90% das neoplasias malignas encontradas na boca. Em casos avançados, quando o controle locoregional já não é possível somente com o tratamento cirúrgico mais a radioterapia, a quimioterapia adjuvante e neoadjuvate torna-se uma importante modalidade de tratamento para aumentar a qualidade de vida e sobrev
Publicado em: 2009
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18. In vitro evidence for a new therapeutic approach in renal cell carcinoma
PURPOSE: Renal cell carcinoma (RCC) is the most lethal among the common urologic malignancies, comprising 3% of all human neoplasias; approximately 40% of patients eventually die of cancer progression. One third of patients who present with metastatic disease and up to 40% treated for localized disease generally experience recurrence. RCCs are characterized
International braz j urol. Publicado em: 2008-08
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19. Conditions of mouth status and oral cancer in smokers / Condições orais e câncer de boca em fumantes
The aim of this study was to assess the hypothesis that conditions of mouth status (the use of dentures, recurrent sores by ill-fitting dentures or ill-positioned or broken teeth, frequent intake of hot beverages and irregular or infrequent tooth brushing) may interact with tobacco, alcohol, diet and socioeconomic status in the carcinogenesis of oral cancer.
Publicado em: 2008
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20. Clinical and cytological assessment and HPV prevalence in oral mucosal cells in Fanconis Anemia / Estudo clínico, citológico e de prevalência do papilomavírus humano em mucosa oral na Anemia de Fanconi
Fanconis anemia (FA) is a rare recessive genetic disorder characterized by boné marrow failure, developmental malformations and congenital abnormalities. FA progressive bone marrow failure usually evolves to aplastic anemia and malignant neoplasias, especially acute myeloid leukemia and head and neck squamous cell carcinomas. The risk of malignancies is inc
Publicado em: 2008
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21. Expression of homeobox genes in oral squamous cell carcinoma cell lines, stimulated with EGF and TGF-beta / Expressão de genes homeobox em células de carcinoma epidermóide de boca estimuladas com EGF e TGF-beta
Homeobox genes, vital to many aspects related with cellular growth and differentiation, had been described as deregulated in some cancers. Their role in carcinogenesis, mainly oral squamous cell carcinomas, remains unclear and poorly characterized. Thus, this study had the purpose to evaluate, in cell cultures, the expression profile of six homeobox genes (A
Publicado em: 2008
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22. HPV detection in oral leukoplakia and oral squamous cell carcinoma / "Detecção do HPV em leucoplasias e carcinomas epidermóides orais"
It is still highly controversial whether HPV can be considered an aetiological or risk factor for the development of malignant/premalignant lesions of the oral cavity. There is an agreement that there is at least quantitative evidence to relate HPV and oral carcinogenesis, since in general the studies find a proportional relation between degree of malignancy
Publicado em: 2007
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23. Expressão da acido graxo sintase, ErbB-2, p27 E Skp2 na carinogenese bucal induzida por 1-oxido 4-nitroquinolina em camundongos e efeito antitumoral do Orlistat / Fatty Acid Sintase, ErbB-2, p27 E Skp2 expression in oral carcinogenesis induced by 4-nitroquinoline 1-oxide and antitumoral Orlistat effects
Squamous cell carcinoma of the oral cavity is one of the most common malignant epithelial neoplasms, and a better understanding of its molecular pathways could help the development of new treatment or preventive agents. Several proteins such as Fatty Acid Synthase (FAS), ErbB-2, p27 and Skp2 are involved in the tumorigenesis process. FAS has an enzyme with m
Publicado em: 2007
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24. Evaluation of the tumor inhibitive effect of in natura (Copaifera reticulata) and hand prepared oil in the DMBA-induced oral carcinogenesis model / Avaliação do efeito inibidor tumoral do óleo resina de copaíba in natura (Copaifera reticulata) e manipulado artesanalmente no modelo de carcinogênese bucal experimental DMBA induzida
A Medicina natural tem se apresentado como alternativa para a cura de inúmeras doenças que afetam a população, utilizando-se de plantas da flora brasileira; muito embora ainda não sejam totalmente esclarecidos os princípios ativos, mecanismo de ação e características de citotoxicidade destes produtos. Uma dessas substâncias é um óleo extraído de
Publicado em: 2007