Oral Carcinogenesis
Mostrando 1-12 de 38 artigos, teses e dissertações.
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1. Influence of interleukins on prognosis of patients with oral squamous cells carcinoma
RESUMO O carcinoma de células escamosas é uma neoplasia maligna que afeta as estruturas e os tecidos da cavidade oral. Interleucinas (IL) sintetizadas a partir de um tumor modulam uma cascata de reações que poderá influenciar o prognóstico da doença. Objetiva-se investigar na literatura se as interleucinas são mediadores que influenciam negativamente
J. Bras. Patol. Med. Lab.. Publicado em: 11/11/2019
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2. Vitamin D levels in actinic keratosis: a preliminary study
Abstract: Background: Recent studies that investigated the effect of vitamin D on skin cancer risk have exhibited inconsistent results. Objective: The aim of the study was to evaluate vitamin D status in patients with actinic keratosis. Methods: A cross-sectional study was conducted on 31 patients with actinic keratosis and 29 healthy controls. Serum vita
An. Bras. Dermatol.. Publicado em: 2018-08
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3. High prevalence of human papillomavirus (HPV) in oral mucosal lesions of patients at the Ambulatory of Oral Diagnosis of the Federal University of Sergipe, Northeastern Brazil
Abstract The role of human papillomavirus (HPV) in oral carcinogenesis is still controversial as detection rates of the virus in oral cavity reported in the literature varies greatly. Objective The aim of this study was to evaluate the frequency of HPV infection and its genotypes in patients with oral lesions at the Ambulatory of Oral Diagnosis of the Fede
J. Appl. Oral Sci.. Publicado em: 2017-02
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4. Immunoexpression of cleaved caspase-3 shows lower apoptotic area indices in lip carcinomas than in intraoral cancer
ABSTRACT Objective This study aimed to evaluate apoptosis by assessing cleaved caspase-3 immunoexpression in hyperplastic, potentially malignant disorder (PMD), and malignant tumors in intraoral and lower lip sites. Material and Methods A retrospective study using paraffin blocks with tissues from patients with inflammatory fibrous hyperplasia (IFH), act
J. Appl. Oral Sci.. Publicado em: 2016-08
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5. High occurrence of Fusobacterium nucleatum and Clostridium difficile in the intestinal microbiota of colorectal carcinoma patients
Abstract Colorectal carcinoma is considered the fourth leading cause of cancer deaths worldwide. Several microorganisms have been associated with carcinogenesis, including Enterococcus spp., Helicobacter pylori, enterotoxigenic Bacteroides fragilis, pathogenic E. coli strains and oral Fusobacterium. Here we qualitatively and quantitatively evaluated the pres
Braz. J. Microbiol.. Publicado em: 09/10/2015
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6. Oral potentially malignant disorders in a large dental population
Objectives Oral cancer (OC) may be preceded by clinically evident oral potentially malignant disorders (OPMDs). Oral carcinogenesis is a multistep process that begins as epithelial hyperplasia and progresses to oral epithelial dysplasia and finally to fully malignant phenotypes. The aim of our study was to estimate the prevalence of OPMDs in a large popula
J. Appl. Oral Sci.. Publicado em: 2014-12
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7. Modulatory activity of brazilian red propolis on chemically induced dermal carcinogenesis
PURPOSE:To evaluate modulatory effects of a hydroalcoholic extract of Brazilian red propolis (HERP) on dermal carcinogenesis using a murine model.METHODS: The HERP was used at concentrations of 10, 50 and 100 mg/kg (PROP10, PROP50 and PROP100, respectively) to modulate dermal carcinogenesis induced by the application of 9,10-dimetil-1,2-benzatraceno (DMBA) o
Acta Cir. Bras.. Publicado em: 2014-02
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8. Participação da quimiocina CCL3 na carcinogênese bucal induzida por 4-nitroquinolina-1-óxido em camundongos
The chemokine CCL3 displays a diversity of roles that may contribute to worse prognosis in oral carcinogenesis. The aim of this study was to evaluate the role of CCL3 in 4-nitroquinoline-1-oxide (4NQO)-induced oral carcinogenesis. C57BL/6 (wild type - WT) and CCL3 deficient (CCL3-/-) male mice were treated with 4NQO in drinking water at concentration of 50 �
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/05/2012
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9. Coexpression of p53 and Ki 67 and lack of c-erbB2 expression in oral leukoplakias in India
Oral cancer is commonly preceded by premalignant lesions and conditions. The clinician's ability to identify lesions at an increased risk of cancer development is critical for its control. The purpose of this study was to compare the expression of tumor suppressor gene p53, proliferation marker Ki-67, and oncogene c-erbB2 and to evaluate the relevance of the
Brazilian Oral Research. Publicado em: 2012-06
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10. Prevalência de Candida spp e xerostomia em pacientes com líquen plano oral. Um estudo grupo-controle / Prevalence of Candida spp e xerostomia in patients with oral lichen planus. A controlled study
Enquanto lesões cutâneas do líquen plano (LP) são autolimitantes, suas manifestações orais (LPO) têm comportamento crônico, raramente apresentam remissão espontânea, e podem sofrer transformação maligna, embora subsista controvérsia sobre esta ultima questão. A este respeito, alguns autores têm dado ênfase ao envolvimento da Candida spp. na m
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2011
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11. Immunohistochemical expression of p53, p16 and hTERT in oral squamous cell carcinoma and potentially malignant disorders
Oral carcinogenesis is a multi-step process. One possible step is the development of potentially malignant disorders known as leukoplakia and erytroplakia. The objective of this study was to use immunohistochemistry to analyze the patterns of expression of the cell-cycle regulatory proteins p53 and p16INK4a in potentially malignant disorders (PMD) of the ora
Brazilian Oral Research. Publicado em: 2011-02
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12. Leucoplasias bucais: estudo comparativo entre o grau histológico de displasia, imunoexpressão de hMLH1 e p53 e análise quantitativa de AgNOR
hMLH1 is a protein of the mammalian mismatch repair system (MMR), which maintains genomic stability during repeated duplication. Investigations point to a role of hMLH1 in oral carcinogenesis, and its expression pattern may be related to epigenetic events and microsatellite instability in oral leukoplakias and squamous cell carcinomas. It seems that those al
Publicado em: 2010