Mannan Binding Lectin
Mostrando 1-12 de 29 artigos, teses e dissertações.
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1. Urine screening by Seldi-Tof, followed by biomarker identification, in a Brazilian cohort of patients with Renal Cell Carcinoma (RCC)
Purpose To screen proteins/peptides in urine of Renal Cell Carcinoma (RCC) patients by SELDI-TOF (Surface Enhanced Laser Desorption Ionization - Time of Flight) in search of possible biomarkers. Material and Methods Sixty-one urines samples from Clear Cell RCC and Papillary RCC were compared to 29 samples of control urine on CM10 chip. Mass analysis was p
Int. braz j urol.. Publicado em: 2013-04
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2. Dermatite atÃpica e imunidade inata: associaÃÃo com o polimorfismo do gene da proteÃna ligadora de manose (MBL2)
A dermatite atÃpica apresenta elevada prevalÃncia, principalmente nos paÃses desenvolvidos, o que tem resultado em um importante problema de saÃde pÃblica. Esta tese consta de dois artigos. No primeiro, artigo de revisÃo sob tÃtulo Lectina ligadora de manose (MBL) e sua associaÃÃo clÃnica com dermatite atÃpica, objetivou-se rever algumas das carac
Publicado em: 2008
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3. CaracterizaÃÃo molecular da lectina ligadora de manose (MBL) em indivÃduos com hepatite C
Mannan-binding lectin (MBL), a member of the type-C lectins, is able to bind through multiple sites to various carbohydrate structures and activate complement. Low levels of MBL have been linked with susceptibility to several infectious diseases. Different assays used to MBL determination havenât been able to identify widely its molecular forms in the circu
Publicado em: 2007
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4. Trypanosoma cruzi e o Sistema Complemento: Mecanismos de ativação e o papel do gene CRIT (Complement C2 Receptor Inhibitor Trispanning) na resistência à lise em cepas de classe I e II / Trypanosoma cruzi E O SISTEMA COMPLEMENTO: MECANISMOS DE ATIVAÇÃO E O PAPEL DO GENE CRIT (COMPLEMENT C2 RECEPTOR INHIBITOR TRISPANNING) NA RESISTÊNCIA À LISE EM CEPAS DE CLASSE I E II / Trypanosoma cruzi e o Sistema Complemento: Mecanismos de ativação e o papel do gene CRIT (Complement C2 Receptor Inhibitor Trispanning) na resistência à lise em cepas de classe I e II / Trypanosoma cruzi E O SISTEMA COMPLEMENTO: MECANISMOS DE ATIVAÇÃO E O PAPEL DO GENE CRIT (COMPLEMENT C2 RECEPTOR INHIBITOR TRISPANNING) NA RESISTÊNCIA À LISE EM CEPAS DE CLASSE I E II
Trypanosoma cruzi, the agent of Chagas disease, infects 18 million people in Latin America. T. cruzi has an heteroxicenous life cycle infecting vertebrates and invertebrate hosts. Two classes of T. cruzi have been proposed based on molecular markers, the class I with a sylvatic life cycle infecting mostly marsupials, while class II parasites have a domestic
Publicado em: 2006
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5. Differential activity of a lectin from Solieria filiformis against human pathogenic bacteria
A lectin isolated from the red alga Solieria filiformis was evaluated for its effect on the growth of 8 gram-negative and 3 gram-positive bacteria cultivated in liquid medium (three independent experiments/bacterium). The lectin (500 µg/mL) stimulated the growth of the gram-positive species Bacillus cereus and inhibited the growth of the gram-negative speci
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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6. Mannan-Binding Lectin Enhances Susceptibility to Visceral Leishmaniasis
Levels of the serum opsonin mannan-binding lectin (MBL) were directly correlated with the probability of developing visceral leishmaniasis. Monocytes infected with MBL-opsonized Leishmania chagasi promastigotes secreted higher levels of tumor necrosis factor alpha and interleukin-6 than cells infected with nonopsonized parasites. Our findings indicate that M
American Society for Microbiology.
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7. Effect of Capsulation of Opportunistic Pathogenic Bacteria on Binding of the Pattern Recognition Molecules Mannan-Binding Lectin, L-Ficolin, and H-Ficolin
Mannan-binding lectin (MBL), L-ficolin, and H-ficolin are pattern recognition molecules of the innate immune system. We investigated their ability to bind to different serotypes and noncapsulated variants of two gram-positive bacterial species, Streptococcus pneumoniae and Staphylococcus aureus. MBL did not bind to capsulated S. aureus or capsulated S. pneum
American Society for Microbiology.
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8. Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: Mannan-binding proteindependent cell-mediated cytotoxicity
Mannan-binding protein (MBP), a Ca2+-dependent mammalian lectin specific for mannose and N-acetylglucosamine, is an important serum component associated with innate immunity. MBP activates complement and functions as a direct opsonin on binding to mannooligosaccharide-bearing pathogens. We have found that MBP recognizes and binds specifically to oligosacchar
The National Academy of Sciences.
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9. Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi
Recent identification of a C3-like gene in sea urchins revealed the presence of a complement system in invertebrates. To elucidate further the components and function of the pre-vertebrate complement system, we attempted to isolate an ascidian (urochordata) C3 convertase. After identification of C3 cDNA from Halocynthia roretzi, a Japanese ascidian, reverse
The National Academy of Sciences of the USA.
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10. Lectinophagocytosis of encapsulated Klebsiella pneumoniae mediated by surface lectins of guinea pig alveolar macrophages and human monocyte-derived macrophages.
Macrophages express a mannose/N-acetylglucosamine-specific lectin which serves as a receptor for nonopsonic phagocytosis of mannose-coated particles. We have examined the binding to guinea pig alveolar macrophages in a serum-free medium of 16 Klebsiella pneumoniae serotypes and of the capsular polysaccharides isolated from 7 of these serotypes. Only five pol
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11. Mannan-binding lectin deficiency modulates the humoral immune response dependent on the genetic environment
Mannan-binding lectin (MBL) is a plasma protein implicated in innate immune defence against a broad range of microorganisms, including viruses. It is also thought that MBL plays a role in the recruitment of the specific clonal immune response. This was studied by injecting soluble hepatitis B surface antigen (HBsAg) intravenously into mice deficient in both
Blackwell Science Inc.
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12. Possible mechanism for flocculation interactions governed by gene FLO1 in Saccharomyces cerevisiae.
A model is proposed for the mechanism of flocculation interactions in yeasts in which flocculent cells have a recognition factor which attaches to alpha-mannan sites on other cells. This factor may be governed by the expression of the single, dominant gene FLO1. Isogenic strains of Saccharomyces cerevisiae, differing only at FLO1 and the marker genes ade1 an