Skeletal Muscle Atrophy
Mostrando 13-24 de 71 artigos, teses e dissertações.
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13. Functional and morphological effects of resistance exercise on disuse-induced skeletal muscle atrophy
Abstract The reduction of skeletal muscle loss in pathological states, such as muscle disuse, has considerable effects in terms of rehabilitation and quality of life. Since there is no currently effective and safe treatment available for skeletal muscle atrophy, the search for new alternatives is necessary. Resistance exercise (RE) seems to be an important t
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-11
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14. Efeito da suplementação com leucina sobre a resposta atrófica da musculatura esquelética induzida pelo uso de dexametasona / Effects of leucine supplementation on skeletal muscle atrophy dexamethasone-induced
A dexametasona (DEXA) é um potente agente imunossupressor e antiinflamatório, mas apresenta importantes efeitos colaterais, tais como a atrofia muscular e a resistência à ação da insulina nos músculos esqueléticos. Neste contexto, a suplementação com leucina poderia representar uma estratégia nutricional terapêutica capaz de limitar os efeitos co
Publicado em: 2011
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15. Efeito do treinamento físico aeróbico sobre a atrofia muscular associada à insuficiência cardíaca: contribuição do sistema ubiquitina proteassoma dependente de ATP / Effects of aerobic exercise training on skeletal muscle atrophy associated with heart failure: role of ubiquitin-proteasome pathway
A atrofia está associada ao aumento da degradação protéica em doenças sistêmicas, sendo o sistema proteolítico ubiquitina proteassoma (SUP) uma das principais vias envolvidas. Contudo, pouco é conhecido sobre a contribuição do SUP à atrofia desencadeada pela insuficiência cardíaca (IC). Sabendo dos benefícios do treinamento físico aeróbico (T
Publicado em: 2010
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16. Effects of exercise training on atrophy gene expression in skeletal muscle of mice with chronic allergic lung inflammation
We evaluated the effects of chronic allergic airway inflammation and of treadmill training (12 weeks) of low and moderate intensity on muscle fiber cross-sectional area and mRNA levels of atrogin-1 and MuRF1 in the mouse tibialis anterior muscle. Six 4-month-old male BALB/c mice (28.5 ± 0.8 g) per group were examined: 1) control, non-sensitized and non-trai
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-04
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17. Efeitos do treinamento resistido associado com decanoato de nandrolona sobre a expressão gênica de moduladores de vias de hipertrofia e atrofia do músculo esquelético
Androgenic-anabolic steroids (AAS) are spread among athletes and no athletes in order to improve performance or physical appearance. AAS targets the satellite cells in skeletal muscles, which are the major precursors of the skeletal muscle, and are essential for muscle growth and repair. When activated, in the presence of several factors, including myogenic
Publicado em: 2009
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18. Ação da laserterapia de baixa intensidade (830nm) na regeneração muscular de ratos idosos
The elderly still go through physical changes, especially musculoskeletal disorders such as sarcopenia, changes in central and peripheral nervous system, blood hypoperfusion, regenerative changes contributing to atrophy and muscle weakness, undermining the activities of daily living (AVL). The regenerative process happens about the determination, proliferati
Publicado em: 2009
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19. Efeito da inflamação articular aguda sobre a morfologia e a expressão gênica dos músculos sóleo e tibial anterior de ratos
Clinic evidences show that joint injuries affect muscles related to that joint making them more sensitive to atrophy and loss of force. However, muscle molecular responses in those conditions has not been investigated yet. Objective: To evaluate the effects of tibiotarsal acute joint inflammation on the expression of genes related to muscle atrophy (atrogin-
Publicado em: 2008
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20. Expressão de fatores de regulação miogenica e metaloproteinases no musculo estriado esqueletico de ratos com insuficiencia cardiaca / Myogenic regulatory factors and metalloproteinase expression in rat skeletal muscle with heart failure
Background: Heart failure (HF) is associated with a skeletal muscle myopathy with increased expression of fast myosin heavy chains (MHC) and extracellular matrix (ECM) alterations. The skeletal muscle-specific molecular regulatory mechanisms controlling MHC expression during HF have not been described. Myogenic regulatory factors (MRF), a family of transcrip
Publicado em: 2006
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21. Efeito do uso de tela reabsorvível (Interceed) sobre a musculatura estriada esquelética após cirurgia de reparo de tendão : estudo experimental em ratos wistar
Interceed is an absorbable sheet made of oxidized cellulose often used to prevent adhesions mainly in gynecology surgeries. OBJECTIVES: to evaluate if there is adhesion reduction after tendon repair when using absorbable sheet (Interceed) as a physical barrier of protection. MATERIAL AND METHOD: 20 Wistar rats divided in 3 groups were used. The first group,
Publicado em: 2006
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22. Effect of salbutamol on innervated and denervated rat soleus muscle
The objective of the present investigation was to perform a 14-day time-course study of treatment with salbutamol, a ß2 adrenoceptor agonist, on rat soleus muscle in order to assess fiber type selectivity in the hypertrophic response and fiber type composition. Male Wistar rats were divided into four groups: control (N = 10), treated with salbutamol (N = 30
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-12
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23. Effects of neuromuscular electric stimulation during the immobilization in the mechanical properties of the skeletal muscle. / Efeitos da eletroestimulação neuromuscular durante a imobilização nas propriedades mecânicas do músculo esquelético
The neuromuscular electric stimulation (NMES) is an important tool used in sport medicine to accelerate the recovery process. The objective of this study was to analyze the effects of NMES during the immobilization of the gastrocnemius muscle, in lengthened (LP) and shortened positions (SP). Sixty young female rats WISTAR were distributed into six groups and
Publicado em: 2005
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24. Alterações da aorta em ratas portadoras de neoplasia
Cancer cachexia is a systemic disorder composed by physical wasting features and metabolic disturbance. Although skeletal muscle and fat tissue are the most affected structures, atrophy of heart, spleen, liver and kidney has also been described. Clinical and experimental data about alterations due to cachexia of the pre-existing host vessels are rare. The pu
Publicado em: 2000