Short Tandem Repeats Mutation Rates
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Taxas de mutaÃÃo de 14STRs autossÃmicas na populaÃÃo de Pernambuco
A definiÃÃo das taxas de mutaÃÃo dos locos de microssatÃlites ou Short Tandem Repeats (STRs) usados em anÃlises forenses sÃo Ãteis para a correta interpretaÃÃo dos resultados dos perfis genÃticos e para a definiÃÃo dos critÃrios de exclusÃo em testes de paternidade. MutaÃÃes da linhagem germinativa de 14 locos de STRs foram estudadas atravÃ
Publicado em: 2008
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2. Extinction of canid populations by inbreeding depression under stochastic environments in Southwestern Goiás State: a simulation study
A frequently addressed question in conservation biology is what is the chance of survival for a population for a given number of years under certain conditions of habitat loss and human activities. This can be estimated through an integrated analysis of genetic, demographic and landscape processes, which allows the prediction of more realistic and precise mo
Genetics and Molecular Biology. Publicado em: 2007
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3. Possible Role of Natural Selection in the Formation of Tandem-Repetitive Noncoding DNA
A simulation model of sequence-dependent amplification, unequal crossing over and mutation is analyzed. This model predicts the spontaneous formation of tandem-repetitive patterns of noncoding DNA from arbitrary sequences for a wide range of parameter values. Natural selection is found to play an essential role in this self-organizing process. Natural select
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4. Vntr Allele Frequency Distributions under the Stepwise Mutation Model: A Computer Simulation Approach
Variable numbers of tandem repeats (VNTRs) are a class of highly informative and widely dispersed genetic markers. Despite their wide application in biological science, little is known about their mutational mechanisms or population dynamics. The objective of this work was to investigate four summary measures of VNTR allele frequency distributions: number of
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5. Domain-Level Differences in Microsatellite Distribution and Content Result from Different Relative Rates of Insertion and Deletion Mutations
Microsatellites (short tandem polynucleotide repeats) are found throughout eukaryotic genomes at frequencies many orders of magnitude higher than the frequencies predicted to occur by chance. Most of these microsatellites appear to have evolved in a generally neutral manner. In contrast, microsatellites are generally absent from bacterial genomes except in l
Cold Spring Harbor Laboratory Press.