Provisional
Mostrando 13-24 de 292 artigos, teses e dissertações.
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13. [PROVISIONAL] -866G/A and Ins/Del polymorphisms in the UCP2 gene and diabetic kidney disease: case-control study and meta-analysis
Abstract Uncoupling protein 2 (UCP2) decreases reactive oxygen species (ROS) formation by mitochondria. ROS overproduction is a key contributor to the pathogenesis of diabetic kidney disease (DKD). Thus, UCP2 polymorphisms are candidate risk factors for DKD; however, their associations with this complication are still inconclusive. Here, we describe a case-c
Genet. Mol. Biol.. Publicado em: 02/09/2019
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14. [PROVISIONAL] Genome sequence of Shewanella corallii strain A687 isolated from pufferfish (Sphoeroides spengleri)
Abstract We present here the genome sequence of Shewanella corallii strain A687 isolated from pufferfish Sphoeroides spengleri (Family Tetraodontidae). The assembly consists of 5,215,037 bp and contains 284 contigs, with a G+C content of 50.3%. The genus Shewanella comprises 67 recognized species. These bacteria are Gram-negative, rod-shaped, facultatively a
Genet. Mol. Biol.. Publicado em: 02/09/2019
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15. [PROVISIONAL] The combined risk effect among BIN1, CLU and APOE genes in Alzheimer’s disease
Abstract Genome-wide associations studies (GWAS) have been detecting new variants associated with late-onset of Alzheimer’s disease (LOAD), a multifactorial neurodegenerative disorder. The variants rs744373 BIN1, rs11136000 CLU rs3764650 ABCA7 uncovered by GWAS led to different AD pathways, such as metabolism, trafficking and endocytosis of lipids and infl
Genet. Mol. Biol.. Publicado em: 29/08/2019
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16. [PROVISIONAL] Does the chromosomal position of 35S rDNA sites influence their transcription? A survey on Nothoscordum species (Amaryllidaceae)
Abstract 35S ribosomal DNA (rDNA) sites are the regions where the ribosomal genes 18S, 5.8S and 25S, responsible for the formation of the nucleoli, are found. The fact that rDNA sites have non-random distribution on chromosomes suggests that their position on the chromosome may influence their transcription. In order to identify if the preferentially transcr
Genet. Mol. Biol.. Publicado em: 29/08/2019
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17. [PROVISIONAL] Genetic evidence for a species complex within the piranha Serrasalmus maculatus (Characiformes, Serrasalmidae) from three Neotropical River basins based on mitochondrial DNA sequences
Abstract Mitochondrial molecular markers (DNA sequences of D-loop, cytochrome b and cytochrome c oxidase I) were employed to characterize populations of the piranha Serrasalmus maculatus from Upper Paraná, Upper Paraguay and Tocantins River basins. D-loop sequences of S. maculatus population from Paraná-Paraguay River basin exhibited tandem repeats of shor
Genet. Mol. Biol.. Publicado em: 22/08/2019
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18. [PROVISIONAL] Identification of histone methylation modifiers and their expression patterns during somatic embryogenesis in Hevea brasiliensis
Abstract Histone methylation plays a crucial role in various biological processes including from heterochromatin formation to transcriptional regulation. Currently, no information is available regarding histone methylation modifiers in the important rubber-producing plant Hevea brasiliensis. Here, we identified 47 histone methyltransferase (HMT) genes and 25
Genet. Mol. Biol.. Publicado em: 22/08/2019
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19. [PROVISIONAL] Heterochromatin and numeric chromosome evolution in Bignoniaceae, with emphasis on the Neotropical clade Tabebuia alliance
Abstract Bignoniaceae is a diverse family composed of 840 species with Pantropical distribution. The chromosome number 2n = 40 is predominant in most species of the family, with n = 20 formerly being considered the haploid base number. We discuss here the haploid base number of Bignoniaceae and examine heterochromatin distributions revealed by CMA/DAPI fluor
Genet. Mol. Biol.. Publicado em: 19/08/2019
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20. [PROVISIONAL] Low cytomolecular diversification in the genus Stylosanthes Sw. (Papilionoideae, Leguminosae)
Abstract Stylosanthes (Papilionoideae, Leguminosae) is a predominantly neotropical genus with ~ 48 species that includes worldwide important forage species. This study presents the chromosome number and morphology of eight species of the genus Stylosanthes (S. acuminata, S. gracilis, S. grandifolia, S. guianensis, S. hippocampoides, S. pilosa, S. macrocephal
Genet. Mol. Biol.. Publicado em: 19/08/2019
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21. [PROVISIONAL] Non-mosaic partial duplication 12p in a patient with dysmorphic characteristics and developmental delay
Abstract Duplication of the short arm of chromosome 12 is a rare chromosomal abnormality that may arise de novo or result from malsegregation of a balanced parental translocation. This study comprises the clinical description, cytogenetic and cytogenomic analyses and genotype-phenotype correlation in a patient with facial dysmorphism, developmental delay and
Genet. Mol. Biol.. Publicado em: 19/08/2019
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22. [PROVISIONAL] Molecular characterization and transcription analysis of DNA methyltransferase genes in tomato (Solanum lycopersicum)
Abstract DNA methylation plays an important role in plant growth and development, gene expression regulation and maintenance of genome stability. However, only little information regarding development- or stress-related DNA methyltransferases (MTases) genes is available in tomato. Here, we report the analysis of nine tomato MTases which were categorized into
Genet. Mol. Biol.. Publicado em: 19/08/2019
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23. [PROVISIONAL] Growth Hormone Insensitivity (Laron syndrome): report of a new family and review of Brazilian patients
Genet. Mol. Biol.. Publicado em: 12/08/2019
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24. [PROVISIONAL] Boundaries in metagenomic screenings using lacZα-based vectors
Article Metagenomics approaches have been of high relevance for providing enzymes used in diverse industrial applications. In the current study, we have focused on the prospection of protease and glycosyl hydrolase activities from a soil sample by using the lacZα -based plasmid pSEVA232. For this, we used a functional screen based on skimmed milk agar and a
Genet. Mol. Biol.. Publicado em: 12/08/2019