Ntds
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Nanoparticulate drug delivery systems for the treatment of neglected tropical protozoan diseases
Abstract Neglected Tropical Diseases (NTDs) comprise of a group of seventeen infectious conditions endemic in many developing countries. Among these diseases are three of protozoan origin, namely leishmaniasis, Chagas disease, and African trypanosomiasis, caused by the parasites Leishmania spp., Trypanosoma cruzi, and Trypanosoma brucei respectively. These d
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 11/02/2019
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2. Defectos del tubo neural y del ácido fólico: recorrido histórico de una intervención preventiva altamente efectiva
This article gives a broad overview of part of the historical evolution of medical knowledge about neural tube defects (NTD) and the discovery of vitamin B9 or folic acid, as well as some relevant research events that, over the course of several centuries, defined the relationships between the understanding of central nervous system embryology, the discovery
Hist. cienc. saude-Manguinhos. Publicado em: 16/01/2015
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3. Control of neglected disease insect vectors: future prospects for the use of tools based on behavior manipulation-interference
A expressão "doenças tropicais negligenciadas" (NTDs) representa uma série de doenças que afetam a população de países de baixa renda, sendo insetos vetores os responsáveis pela transmissão de grande parte dessas doenças. Ferramentas de controle são necessárias para impedir o contato entre humanos e insetos vetores destas doenças. Este controle
J. Braz. Chem. Soc.. Publicado em: 2014-10
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4. Doenças tropicais negligenciadas: uma nova era de desafios e oportunidades
In an article recently published in Química Nova, entitled "Chemistry Without Borders" ("Química Sem Fronteiras") [Pinto, A. C.; Zucco, C.; Galembeck, F.; Andrade, J. B.; Vieira, P. C. Quim. Nova 2012, 35, 2092], the authors highlighted the important aspects of science and technology with special emphasis on the field of Chemistry and its contributions tow
Quím. Nova. Publicado em: 2013
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5. Performance of super hybrid rice cultivars grown under no-tillage and direct seeding
Good progress has been made in the super hybrid rice (Oryza sativa L.) breeding in China. However, rice yield not only depends on the genetic characteristics but also on the agronomic practices. No-tillage and direct seeding (NTDS) is a simplified cultivation technology that greatly simplifies both land preparation and crop establishment. Aiming to determine
Scientia Agricola. Publicado em: 2012-04
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6. Epidemiologia da giardíase e de geohelmintoses como doenças tropicais negligenciadas em três municípios da Zona da Mata Mineira
Doenças tropicais negligenciadas (DTNs), assim classificadas pela Organização Mundial de Saúde, constituem um grupo de infecções praticamente eliminadas no mundo desenvolvido, mas que persistem em áreas pobres de países de baixa renda. Dentre elas estão a ascaridíase, a tricuríase e a ancilostomíase, cujos agentes etiológicos têm parte de seu c
Publicado em: 2010
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7. Estudo do cariotipo constitucional e dos tecidos envolvidos na lesão de crianças portadoras de defeito do tubo neural (DTN) por meio de analise citogenetica convencional e FISH
The association between chromosomal abnormalities, specially aneuploidies and neural tube defects (NTDs) is well known, principally when NTD is not the only malformation present. Recently, research in animal models, using fluorescence in situ hybridization (FISH) identified aneuploidy in neural tissues. The aims of this work were to identify the frequency of
Publicado em: 2004
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8. Neural tube defects 1974-94--down but not out.
AIMS: To describe accurately the total prevalence of neural tube defects (NTDs) in England and Wales over time, and to provide a benchmark up to 1994. METHODS: National data about NTDs reported as births or terminations are available from 1974-94, but reporting is incomplete. A local register of NTDs covering Oxfordshire/west Berkshire from 1965-94 was used
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9. Loss of mitogen-activated protein kinase kinase kinase 4 (MEKK4) results in enhanced apoptosis and defective neural tube development
Neural tube defects (NTDs) are prevalent human birth defects. Mitogen-activated protein kinases (MAPKs), such as c-Jun N-terminal kinase (JNK), are implicated in facilitating neural tube closure, yet upstream regulators remain to be identified. Here, we show that MAP kinase kinase kinase 4 (MEKK4) is strongly expressed in the developing neuroepithelium. Mice
National Academy of Sciences.
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10. Upper and lower neural tube defects: an alternate hypothesis.
It has been suggested that neural tube defects (NTDs) of the upper type (anencephaly, encephalocele, and thoracic spina bifida) may have a pathogenesis different from those of the lower type (lumbosacral spina bifida), since recurrent cases within a sibship were said always to be concordant with respect to NTD type. Also, spontaneous abortion, additional mal
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11. Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3- dependent development and tumorigenesis
Pax-3 is a transcription factor that is expressed in the neural tube, neural crest, and dermomyotome. We previously showed that apoptosis is associated with neural tube defects (NTDs) in Pax-3-deficient Splotch (Sp/Sp) embryos. Here we show that p53 deficiency, caused by germ-line mutation or by pifithrin-α, an inhibitor of p53-dependent apoptosis, rescues
Cold Spring Harbor Laboratory Press.
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12. Altered regulation of platelet-derived growth factor receptor-α gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins
Mouse models show that congenital neural tube defects (NTDs) can occur as a result of mutations in the platelet-derived growth factor receptor-α gene (PDGFRα). Mice heterozygous for the PDGFRα-mutation Patch, and at the same time homozygous for the undulated mutation in the Pax1 gene, exhibit a high incidence of lumbar spina bifida occulta, suggesting a f
The National Academy of Sciences.