Molecular Mimicry
Mostrando 1-12 de 109 artigos, teses e dissertações.
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1. Two cases of subacute thyroiditis after different types of SARS-CoV-2 vaccination
SUMMARY Although the development of subacute thyroiditis (SAT) following viral infections is well-documented, the actual mechanism has not been clearly elucidated. The occurrence of SAT after vaccination has been reported in several case series and possible mechanisms such as molecular mimicry due to the exposure to viral proteins and/or abnormal reactogenic
Archives of Endocrinology and Metabolism. Publicado em: 2022
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2. Prevalence of virulence genes in strains of Campylobacter jejuni isolated from human, bovine and broiler
Campylobacter jejuni isolates of different origins (bovine, broiler meat, human) were screened by polymerase chain reaction for the presence of 4 genes cdtB, cst-II, ggt, and virB11, previously linked to virulence such as adherence, invasion, colonization, molecular mimicry, and cytotoxin production. In addition, the isolates were screened for the presence o
Braz. J. Microbiol.. Publicado em: 2013-12
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3. Predição In Silico de Epítopos de Microrganismos com Identidade a Autoantígenos Humanos / In Silico Prediction of Microorganism Motifs with Identity to Human Autoantigens
The origin of autoimmune diseases is multifactorial. It involves environmental conditions and genetic predisposition that difficulties its identification. Several researchers have studied the association between infectious agents and autoimmunity, which can be initiated by a process named molecular mimicry. In this case, cross immune responses involving self
Publicado em: 2010
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4. Ações das Hsp65r nativa e sua mutante K409A de Mycobacterium leprae durante o processo de envelhecimento. / The influence of Mycobacterium leprae rHsp65 wild type and its mutant K409A during the ageing process.
As Hsp60 acham-se conservadas em todos os organismos, participando da estruturação de proteínas e em processos crônico-degenerativos. Foi avaliada a ação das Hsp65r WT e sua mutante K409A de M. leprae no envelhecimento. Análises do Tempo Médio de Sobrevida (TMS), titulação dos isótipos, ensaios de avidez e análises histopatológicas foram realiza
Publicado em: 2010
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5. Diferenciación morfológica y molecular de Oleria makrena (Hewitson) y Oleria fumata (Haensch) (Lepidoptera: Ithomiinae)
Oleria (Olerinii tribe) is a genus of great ecological and evolutionary importance among the Ithomiinae (Nymphalidae). Species identification is very complex since most of them are involved in mimicry rings and share large morphological similarities. Ithomiinae specimens collected in the Antioquia Southwest - Colombia, showed confuse wing color pattern gener
Neotropical Entomology. Publicado em: 2009-10
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6. "Determinação de alvos antigênicos na doença reumática cardíaca utilizando phage display" / Identification of molecular markers involved in the pathogenesis of rheumatic heart disease by phage display
Rheumatic heart disease (RHD) patients develop valvar lesions with CD4+ T lymphocytes infiltrating the heart. Molecular mimicry between streptococcal and cardiac proteins recognized by these T cells may explain these auto-aggressive lesions. In the present work we used a Phage Display peptide library to identify cardiac antigens which could be recognized by
Publicado em: 2006
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7. Febre reumática: um modelo animal para uma vacina humana / Rheumatic fever: an animal model for a human disease
A febre reumática é um bom exemplo de uma doença auto-imune deflagrada por um processo infeccioso. Num prazo de uma a quatro semanas após a resolução de uma faringite não tratada por cepas reumatogênicas de S. pyogenes, o organismo de um hospedeiro susceptível desencadeia uma resposta imune contra grandes articulações, coração, tecidos subcutân
Publicado em: 2006
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8. H antigen presence in an Ascaris lumbricoides extract
Previous experiences have demonstrated the same ABO system and P system antigens in A. lumbricoides extracts and in their hosts. The aim was to show the behavior of an A. lumbricoides extract from an O Group patient against monoclonal antibodies of different specificities. Agglutination Inhibition Tests were carried out facing the extract against monoclonal
Revista do Instituto de Medicina Tropical de São Paulo. Publicado em: 2005-06
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9. Avian mycoplasmosis update
Avian mycoplasmas occur in a variety of bird species. The most important mycoplasmas for chickens and turkeys are Mycoplasma gallisepticum (MG), M. synoviae (MS), and M. meleagridis. Besides, M. iowe (MI) is an emerging pathogen in turkeys, but of little concern for chickens. Mycoplasmas are bacteria that lack cell wall and belong to the class Mollicutes. Al
Revista Brasileira de Ciência Avícola. Publicado em: 2005-03
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10. Autoimmunity and molecular mimicry in tropical spastic paraparesis/human T-lymphotropic virus-associated myelopathy
Viruses share antigenic sites with normal host cell components, a phenomenon known as molecular mimicry. It has long been suggested that viral infections might trigger an autoimmune response by several mechanisms including molecular mimicry. More than 600 antiviral monoclonal antibodies generated against 11 different viruses have been reported to react with
Brazilian Journal of Medical and Biological Research. Publicado em: 2005-02
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11. Molecular mimicry--hypothesis or reality?
A number of observations support molecular mimicry as a possible pathogenetic mechanism in diseases such as acute rheumatic fever, reactive arthritis after enteric infection or associated with Reiter's syndrome, myasthenia gravis, or even in rheumatoid arthritis. Molecular mimicry can be defined as a sharing of epitopes in linear or 3-dimensional presentatio
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12. Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry.
Molecular mimicry, normally defined by the level of primary-sequence similarities between self and foreign antigens, has been considered a key element in the pathogenesis of autoimmunity. Here we describe an example of molecular mimicry between two overlapping peptides within a single self-antigen, both of which are recognized by the same human self-reactive