Minimal Residual Disease
Mostrando 1-12 de 49 artigos, teses e dissertações.
-
1. Endoscopic-Assisted Canal Wall-up Tympanomastoidectomy for Reduction of Residual Cholesteatoma
Abstract Introduction The treatment of cholesteatoma is generally surgical, and the major obstacle is the high prevalence of recidivism. The endoscopic ear surgery technique is proposed to minimize this problem. Objectives To utilize endoscopes to visualize and manipulate cholesteatoma residues after microscopic removal Methods Cross-sectional study. Thir
International Archives of Otorhinolaryngology. Publicado em: 2022
-
2. Pediatric population with cystic fibrosis in the centre of Portugal: candidates for new therapies
Abstract Objectives: Cystic fibrosis (CF) is a severe autosomal recessive disease that results from mutations in a gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a chloride channel. This study aims to characterize the clinical and genetic features of a cohort of pediatric people with CF (PwCF) in the center of Portugal
Jornal de Pediatria. Publicado em: 2022
-
3. Influence of minimal residual disease by multiparametric flow cytometry at day 15 of induction in risk stratification of children with B-cell acute lymphoblastic leukemia treated at a referral hospital in southern Brazil
ABSTRACT Background: The minimal residual disease (MRD) is the most important prognostic factor for acute lymphoblastic leukemia (ALL) in children. This study aimed to investigate the influence of detecting the MRD by the multiparametric flow cytometry (MFC) at day 15 (D15) of the induction on the analysis of the risk group classifications of the different
Hematol., Transfus. Cell Ther.. Publicado em: 2020-10
-
4. Multidisciplinary diagnostics of chronic lymphocytic leukemia: European Research Initiative on CLL - ERIC recommendations
ABSTRACT Recent advances in chronic lymphocytic leukemia (CLL) includes description of disease genomic landscape, inclusion of prognostic relevant genetic tests in CLL workflow and evaluation of minimal residual disease (MRD)1 in parallel with the increase availability of novel therapy agents.In this review, the theoretical and practical aspects of response
Hematol., Transfus. Cell Ther.. Publicado em: 2020-09
-
5. Does Cystatin C have a role as metabolic surrogate in peritoneal dialysis beyond its association with residual renal function?
RESUMO Introdução: Tem sido sugerido que os níveis de cistatina C são modificados pela obesidade e inflamação. Além disso, a cistatina C tem sido associada a eventos cardiovasculares e desfechos de mortalidade. Objetivo: Estudar a associação da cistatina C com o perfil metabólico e doença cardiovascular de pacientes em diálise peritoneal. Mét
J. Bras. Nefrol.. Publicado em: 02/12/2019
-
6. Robot - assisted laparoscopic retroperitoneal lymph node dissection in testicular tumor
ABSTRACT Introduction and objective Retroperitoneal lymph node dissection (RPLND) is indicated for patients with non-seminomatous germ cell tumor (NSGCT) with residual disease after chemotherapy. Although the gold standard approach is still the open surgery, few cases of robot-assisted laparoscopic RPLND have been described. Herein, we aim to present the s
Int. braz j urol.. Publicado em: 2017-02
-
7. Minimal residual disease detection in Tunisian B-acute lymphoblastic leukemia based on immunoglobulin gene rearrangements
IGH gene rearrangement and IGK-Kde gene deletion can be used as molecular markers for the assessment of B lineage acute lymphoblastic leukemia (B-ALL). Minimal residual disease detected based on those markers is currently the most reliable prognosis factor in B-ALL. The aim of this study was to use clonal IGH/IGK-Kde gene rearrangements to confirm B-ALL diag
Braz J Med Biol Res. Publicado em: 16/01/2017
-
8. Comparison between qualitative and real-time polymerase chain reaction to evaluate minimal residual disease in children with acute lymphoblastic leukemia
ABSTRACT Introduction: Minimal residual disease is an important independent prognostic factor that can identify poor responders among patients with acute lymphoblastic leukemia. Objective: The aim of this study was to analyze minimal residual disease using immunoglobulin (Ig) and T-cell receptor (TCR) gene rearrangements by conventional polymerase chain
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-12
-
9. Proposal for the standardization of flow cytometry protocols to detect minimal residual disease in acute lymphoblastic leukemia
ABSTRACT Minimal residual disease is the most powerful predictor of outcome in acute leukemia and is useful in therapeutic stratification for acute lymphoblastic leukemia protocols. Nowadays, the most reliable methods for studying minimal residual disease in acute lymphoblastic leukemia are multiparametric flow cytometry and polymerase chain reaction. Both
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-12
-
10. Qualitative polymerase chain reaction versus quantitative polymerase chain reaction for the detection of minimal residual disease in children with acute lymphoblastic leukemia
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-12
-
11. Gene rearrangement study for minimal residual disease monitoring in children with acute lymphocytic leukemia
OBJECTIVE To detect markers for minimal residual disease monitoring based on conventional polymerase chain reaction for immunoglobulin, T-cell receptor rearrangements and the Sil-Tal1 deletion in patients with acute lymphocytic leukemia. METHODS Fifty-nine children with acute lymphocytic leukemia from three institutions in Minas Gerais, Brazil, were pros
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
-
12. Padronização de método molecular para detecção de doença residual mínima (DRM) em crianças portadoras de leucemia linfóide aguda tratadas no Distrito Federal
A leucemia linfóide aguda (LLA) é uma neoplasia proveniente da expansão clonal de precursores linfóides imaturos, sendo o câncer mais comum na infância. O tratamento das LLAs da infância constitui exemplo de sucesso terapêutico, e as taxas de sobrevida livre globais de 70-80% alcançadas nos últimos anos são decorrentes da melhora no diagnóstico,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/03/2012