Iontophoresis
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. Erratum: Effect of iontophoresis on fluoride uptake in enamel with artificial caries lesion
Braz. oral res.. Publicado em: 09/09/2019
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2. Effect of iontophoresis on fluoride uptake in enamel with artificial caries lesion
Abstract: Iontophoresis is a noninvasive technique, based on the application of a constant low-intensity electric current to facilitate the release of a variety of drugs, whether ionized or not, through biological membranes. The objective of this research was to evaluate the effect of iontophoresis using different electric current intensities on the uptake o
Braz. oral res.. Publicado em: 16/05/2019
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3. Physical methods for topical skin drug delivery: concepts and applications
Topical drug delivery is an interesting approach to treat skin diseases and to avoid pain and low patient compliance in cases where a systemic delivery is required. However, the stratum corneum, which is the outermost skin layer, strongly protects the body from the entrance of substances, especially those hydrophilic. In this context, different physical meth
Braz. J. Pharm. Sci.. Publicado em: 08/11/2018
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4. Penile microvascular endothelial function in hypertensive patients: effects of acute type 5 phosphodiesterase inhibition
The primary aim of this study was to evaluate penile endothelial microvascular function in patients with primary arterial hypertension and age-matched normotensive subjects using laser speckle contrast imaging (LSCI). Additionally, we analyzed the acute penile microvascular effects induced by oral phosphodiesterase type 5 inhibitor (sildenafil; SIL) administ
Braz J Med Biol Res. Publicado em: 11/01/2018
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5. Iontophoresis on minoxidil sulphate-loaded chitosan nanoparticles accelerates drug release, decreasing their targeting effect to hair follicles
The experiments described in this paper tested the hypothesis whether iontophoresis applied on a chitosan nanoparticle formulation could combine the enhanced drug accumulation into the follicular casts obtained using iontophoresis and the sustained drug release, reducing dermal exposure, provided by nanoparticles. Results showed that even though iontophoresi
Quím. Nova. Publicado em: 2017-02
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6. Iontoforese: princípios e aplicações
Introdução A iontoforese é uma técnica não invasiva utilizada para aumentar, de forma controlada, a penetração transdermal de substâncias através das camadas da pele (epiderme, derme e hipoderme). O avanço tecnológico nas últimas décadas proporcionou uma redução no custo dos equipamentos necessários à sua aplicação, o que possibilitou a e
Fisioter. mov.. Publicado em: 2014-09
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7. Ascorbic acid iontophoresis for chondral gain in rats with arthritis
OBJECTIVES: To examine the cellularity and thickness of the articular cartilage of the femur in rats with arthritis after treatment with iontophoresis. METHODS: To evaluate these objectives, a histological analysis was performed on hematoxylin and eosin, where cellularity and cartilage thickness were observed and evaluated qualitatively and quantitativ
Acta ortop. bras.. Publicado em: 2014-07
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8. Comportamento eletroquímico e avaliação da difusão in vitro do α-tocoferol associado à iontoforese
Iontophoresis is a method of administering substances through the skin, which uses electrical current or potential to promote transdermal delivery. We focused on α-tocopherol (vitamin E), a natural antioxidant able to reduce or block the oxidation reactions induced by free radicals in biological membranes. The aim of this study was to perform electrochemica
Quím. Nova. Publicado em: 2014
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9. Zinc sulphate administered by transdermal iontophoresis improves breaking strength of surgical wounds in skin of alloxan-induced diabetic rats
PURPOSE:To investigate the effect of zinc sulphate administered by transdermal iontophoresis (TDI) on mechanical resistance of surgical wounds performed in the skin of diabetic rats. METHODS:One hundred and sixty male Wistar rats weighing approximately 250g were submitted to an incision surgery at the anterior region of abdomen and randomly distributed into
Acta Cir. Bras.. Publicado em: 2013-08
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10. Synergistic effect of iontophoresis and chemical enhancers on transdermal permeation of tolterodine tartrate for the treatment of overactive bladder
PurposeThe objective of the study was to evaluate the synergistic transdermal permeation effect of chemical enhancers and iontophoresis technique on tolterodine tartrate (TT) transdermal gel and to evaluate its pharmacokinetic properties.Materials and MethodsTaguchi robust design was used for optimization of formulations. Skin permeation rates were evaluated
Int. braz j urol.. Publicado em: 2013-01
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11. Repeatability of the evaluation of systemic microvascular endothelial function using laser doppler perfusion monitoring: clinical and statistical implications
OBJECTIVE: An awareness of the repeatability of biological measures is required to properly design and calculate sample sizes for longitudinal interventional studies. We investigated the day-to-day repeatability of measures of systemic microvascular reactivity using laser Doppler perfusion monitoring. METHODS: We performed laser Doppler perfusion monitoring
Clinics. Publicado em: 2011
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12. Dendrímeros como carreadores da protoporfirina IX para a terapia fotodinâmica tópica do câncer de pele / Dendrimers as drug carriers for protoporphyrin IX to topical photodynamic therapy of skin cancer.
A protoporfirina IX (PpIX) é uma substância fotodinâmicamente ativa, entretanto, devido a sua alta lipofilia apresenta dificuldades para penetrar nas camadas mais profundas da pele, não sendo administrada topicamente. Assim, o objetivo deste trabalho é estudar a influência de diferentes tipos de dendrímeros de poliamidoamina (PAMAM) na solubilidade, p
Publicado em: 2011