Insertion Deletion Polymorphisms
Mostrando 1-12 de 75 artigos, teses e dissertações.
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1. A meta-analysis on the association of genetic polymorphism of the angiotensin-converting enzyme and coronary artery disease in the chinese population
RESUMO OBJETIVO: Investigar a associação entre o polimorfismo de inserção ou deleção do genótipo do gene da enzima conversora da angiotensina (ACE) e a susceptibilidade da etnia Han chinesa para a doença arterial coronariana (DAC). Métodos: Foi realizada uma pesquisa abrangente para o valor de OR (Odds Ratio) de contraste entre o grupo de polimorf
Rev. Assoc. Med. Bras.. Publicado em: 22/07/2019
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2. The relationship between of ACE I/D and the MTHFR C677T polymorphisms in the pathophysiology of type 2 diabetes mellitus in a population of Brazilian obese patients
ABSTRACT Objectives This study aimed to evaluate the frequencies of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) and methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphisms in obese patients with and without type 2 diabetes mellitus (T2DM). Subjects and methods These polymorphisms were analyzed by polymerase chain reac
Arch. Endocrinol. Metab.. Publicado em: 2018-02
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3. Association of polymorphisms within the Renin-Angiotensin System with metabolic syndrome in a cohort of Chilean subjects
ABSTRACT Objective Metabolic syndrome (MetS) is associated with hypertension, obesity and dyslipidemia. Thus, genetic variants related with these conditions may modulate its development. We evaluated the effect of polymorphisms in the renin-angiotensin system (RAS) on metabolic syndrome risk in a cohort of Chilean subjects. Subjects and methods A total of
Arch. Endocrinol. Metab.. Publicado em: 23/02/2016
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4. Single Nucleotide Polymorphisms in IGFBP-2 Gene and Their Associations with Body Weight Traits on Jinghai Yellow Chicken
ABSTRACT Insulin-like growth factor binding protein-2 (IGFBP-2) regulates a broad spectrum of biological activities involved in growth, development, and differentiation. This study aimed at comparing polymorphisms in intron2 of the IGFBP-2 gene among four chicken breeds and at analyzing the associations between its genotypes and body weight in Jinghai Yellow
Rev. Bras. Cienc. Avic.. Publicado em: 2015-12
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5. HLA-G polymorphism in mother-child transmission of HIV-1 / Polimorfismo do HLA-G na transmissão materno-infantil do HIV-1
The main way of HIV-1 infection in children is mother-child transmission (MTCT). TMI rates estimates for HIV-1 are 3% in pregnant women in antiretroviral therapy and 25 to 30% for untreated ones. Despite the viral exposure during pregnancy, most newborns are not vertically infected, suggesting the existence of protective barriers to TMI of HIV-1. Several fac
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/12/2012
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6. Utilização de sistema multiplex de marcadores do tipo INDELs em identificação humana por DNA / Use of multiplex system with INDELs markers in human identification by DNA
Os INDELs são polimorfismos de comprimento, gerados a partir de inserções e/ou deleções de um ou mais nucleotídeos. Os marcadores INDELs, que estão amplamente distribuídos pelo genoma e se caracterizam pela alta estabilidade devido à baixa taxa mutacional (10-9), podem ser analisados a partir da amplificação por PCR (Reação em Cadeia da Polimera
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/05/2012
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7. Influência dos genes HLA classe I na progressão para a Aids em indivíduos HIV positivos
The AIDS epidemic is characterized by an extreme heterogeneity in the clinical course of HIV-1 infection. Whereas some individuals progress to AIDS within three years after seroconversion, a small percentage, called long-term nonprogressors, remain asymptomatic and maintain stable T-CD4+ cell counts for more than 10 years. The role of HLA class I molecules,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2012
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8. Relações morfométricas e genética populacional de Culex quinquefasciatus (Diptera: Culicidae) / Morphometric relationships and population genetics of Culex quinquefasciatus
Objective. The Culex (Culex) quinquefasciatus Say 1823 is widely distributed in human settlements, and is a vector in the transmission cycles of pathogens such as arboviruses and filarids. This species belongs to Cx pipiens complex, whose main characteristic is the morphologic similarity of their species. This study aimed to characterize genetic and morpholo
Publicado em: 2011
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9. DNA tests probe the genomic ancestry of Brazilians
We review studies from our laboratories using different molecular tools to characterize the ancestry of Brazilians in reference to their Amerindian, European and African roots. Initially we used uniparental DNA markers to investigate the contribution of distinct Y chromosome and mitochondrial DNA lineages to present-day populations. High levels of genetic ad
Brazilian Journal of Medical and Biological Research. Publicado em: 11/09/2009
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10. Identificação e validação de marcadores moleculares indel e SNP para lipoxigenases de sementes de soja / Identification and validation of indel and SNP molecular markers for soybean seed lipoxygenases
The oxidative degradation of fatty acids from soybean oil fraction, that occurs during the grain processing, develop a flavor of unripe been that modify the palatability and therefore the acceptability of soybean products, resulting in problems for the food industry. The enzyme lipoxygenases (linoleate: O2 oxidoreductase, EC 1.13.11.12), that catalyses this
Publicado em: 2009
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11. Analysis of renin-angiotensin-aldosterone system gene polymorphisms in resistant hypertension
Essential hypertension is a disease multifactorially triggered by genetic and environmental factors. The contribution of genetic polymorphisms of the renin-angiotensin-aldosterone system and clinical risk factors to the development of resistant hypertension was evaluated in 90 hypertensive patients and in 115 normotensive controls living in Southwestern Braz
Brazilian Journal of Medical and Biological Research. Publicado em: 2007-03
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12. Desenvolvimento e aplicação de polimorfismos de inserção: deleção do cromossomo x em genética forense
Nowadays the human genetic identification its based on the utilization of a set of autosomal markers, the microsatellites, which fulfils the majority of the forensic genetic labs requirements. However, there are some situations when that the usual autosomal microsatellites dont always offer good results. Those situations include cases where the genetic sampl
Publicado em: 2007