Immune Tolerance
Mostrando 25-36 de 348 artigos, teses e dissertações.
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25. Estudo sobre os efeitos de celulas dendriticas moduladas com agentes pro-E anti-inflamatorio ou com drogas inibidoras do metabolismo de L-arginina sobre o curso da resposta imune de camundongos / Study on the effects of dendritic cells modulated with agents pro and anti inflammatory or inhibitors of the metabolism of L-arginine on the course of the immune response in mice
As células dendríticas (DCs) desempenham um papel central na iniciação de respostas de células T. Neste trabalho, investigamos os efeitos de células dendríticas derivadas da medula óssea (BMDC) sobre a resposta imune de camundongos BALB/c e DO11. 10. Observou-se que a modulação de BMDCs com LPS+TNF-α elevou a expressão de CD80, CD86 e CD40 e
Publicado em: 2010
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26. Da tolerância oral e seus efeitos indiretos na transferência adotiva singênica e na rejeição de aloenxertos
Oral tolerance is characterized by a reduction in specific immunological activities to a protein previously given by oral route. Parenteral exposure to antigens to which oral tolerance had been previously induced affects (inhibits) immunological activities connected to unrelated antigens, a phenomenon we have called indirect effects of oral tolerance. Herein
Publicado em: 2009
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27. The role of HSP 60 in leucocytes cells of bovine placenta / O papel da HSP 60 nas células leucocitárias da placenta bovina
The maternal-fetal tolerance involves, besides the immune system, many peculiarities regarding the type of placenta and placentation. The bovine placenta is considered not invasive and, as consequence of a superficial implantation without endometrial invasion, it establishes itself as complex barrier that interposes between the maternal and fetal circulation
Publicado em: 2009
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28. Efeitos do treinamento físico aeróbico de baixa intensidade na inflamação alérgica crônica e na resposta imune de camundongos sensibilizados / Effects of the aerobic physical training of decrease intensity in the chronic allergic inflammation and in the immune response of mice sensitized
The physical training (PT) is part of the pulmonary rehabilitation of asthmatic patients and seems to reduce the number of crises, the use of medicine, the broncoespasm prompted by the exercise and increase the tolerance to the effort and the quality of life. Despite of these benefits, a few studies have investigated possible anti-inflammatory effects trigge
Publicado em: 2009
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29. Efeitos da administração aguda e prolongada de diazepam sobre parâmetros imunológicos de ratos / Effects of acute and long-term diazepam administration on rat immune parameters
Os benzodiazepínicos (BDZ) são amplamente utilizados no tratamento da ansiedade. Aumentam a neurotransmissão GABAérgica por ação em sítios receptores específicos para BDZ presentes no complexo ionóforo no canal do receptor GABAA, onde modulam alostericamente suas atividades. Porém, além de atuar nesses receptores, têm sido relatado, também, a ex
Publicado em: 2009
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30. Cromoblastomicose: à procura do modelo experimental murino. / Chromoblastomycosis: searching for experimental murine model.
This study was prompted by the lack of a satisfactory chronic infection animal model for studies of experimental chromoblastomycosis and the fact that very little is known about the infective fungal forms of Fonsecaea pedrosoi. First, we investigated the infective potential of different mycelial forms of F. pedrosoi, hyphae, conidia and conidiogenous cells,
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/12/2008
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31. Efeitos imunológicos da administração oral de ovalbumina encapsulada em lipossomas
Oral administration of protein antigens, such as ovalbumin, may result in induction of either tolerance or immunization. Induction of immune responses is of great interest for development of oral vaccines. On the other hand, oral tolerance may represent a therapeutic solution to allergic and auto-immune diseases. Induction of oral tolerance depends on many f
Publicado em: 2008
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32. Analysis of the promiscuous gene expression in the thymus of NOD (non obese diabetic) mice during onset of type 1 diabetes mellitus / Análise da expressão gênica promíscua no timo de camundongos NOD (non obese diabetic) durante a emergência do Diabetes melitus tipo 1
Immunologic tolerance is an essential property of the immune system, which controls immune reactions directed against the body self components. The thymus is seen as the main organ involved with the tolerance induction to self antigens, which are expressed by the thymic cells (central tolerance), while the tolerance induction to the diverse other peripheral
Publicado em: 2008
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33. Genic expression alterations in the tolerance to LPS : B lymphocyte in the genic regulation of the tolerance / Alterações de expressão gênica na tolerância ao LPS: análise da participação dos linfócitos B na regulação gênica da tolerância
Sepses are caused by microorganisms such as: Gram-negative bacteria, Gram-positive bacteria, fungus and virus. Several sepses and the septic shock have been associated with the mortality rates from 40 to 60%. One of the most important events for the septic evolution is the apoptosis cells of the immune system. The cells immune system elimination compromises
Publicado em: 2008
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34. Dendritic cells and the 60kDa heat shock protein (Hsp60): strategies for immunoregulation in the mouse immune system / Células dendríticas e a proteína de choque térmico 60KDA (HSP60): estratégias para imunorregulação do sistema imune murino
The induction of tolerance to allotransplant without the help of immunosupressive drugs is one of the major challenges in immunology. Considering the tolerogenic potential of dendritic cells and the immunoregulatory activity of Hsp60, our objective was to determine the capacity of dendritic cells (DCs) of inducing immunoregulation through the interaction wit
Publicado em: 2008
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35. Efeito do levamisol sobre o desempenho produtivo e como mitigador do estresse ao transporte em matrinxã (Brycon amazonicus)
In the present work three experiments were carried out in order to evaluate the effects of dietary levamisole supplementation on growth performance and its efficacy to mitigate stress in matrinxã, Brycon amazonicus. In the first experiment (Chapter 2), the tolerance of matrinxã to Aeromonas hydrophila was verified, through the 96-h LD50 (lethal dose for 50
Publicado em: 2008
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36. The use of stem cells for the treatment of autoimmune diseases
Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to conventional therapy. The use of high doses of drugs in such cases results in the need for bone marrow reconstitution
Brazilian Journal of Medical and Biological Research. Publicado em: 29/10/2007