Immune Tolerance
Mostrando 13-24 de 348 artigos, teses e dissertações.
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13. Antifungal susceptibilities of Cryptococcus species complex isolates from AIDS and non-AIDS patients in Southeast China
Cryptococcus spp. are common causes of mycoses in immunocompromised patients. To determine the drug susceptibilities of clinical Cryptococcus spp. isolates, the characteristics of 61 clinical Cryptococcus spp. complex isolates and their antifungal susceptibilities were investigated, including 52 C. neoformans and 9 C. gattii isolates collected at Shanghai be
Brazilian Journal of Infectious Diseases. Publicado em: 2012-04
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14. Análise do fenômeno da imunotolerância na fotocarcinogênese em lábio / Analysis of the immunotolerance phenomenon of in the lip photocarcinogenesis
Ultraviolet radiation (UV) is the main cause of non-melanoma skin cancer and induces biological effects that promote photocarcinogenesis by causing mutations directly on DNA. However, there seems to be an indirect effect, which induces immunosuppession. The physiological phenomenon of immune tolerance, which is responsible for the prevention of autoimmune di
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/12/2011
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15. Perfil imunoistoquímico de linfócitos T regulatórios no pênfico foliáceo endêmico através da expressão do marcador Foxp3 / Immunohistochemical profile of regulatory T cell Foxp3 marker in endemic pemphigus foliaceus
Introdução: Os linfócitos T regulatórios CD4+CD25+Foxp3+ (Tregs) desempenham um papel fundamental na manutenção da tolerância aos antígenos próprios e no controle da magnitude da resposta imunológica. Alterações quantitativas ou funcionais foram descritas em diversos distúbios auto-imunes. O pênfigo foliáceo endêmico (PFE) é uma doença bolh
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/08/2011
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16. Cytokines and T-Lymphocute count in patients in the acute and chronic phases of Bartonella bacilliformis infection in an endemic area in peru: a pilot study
Human Bartonellosis has an acute phase characterized by fever and hemolytic anemia, and a chronic phase with bacillary angiomatosis-like lesions. This cross-sectional pilot study evaluated the immunology patterns using pre- and post-treatment samples in patients with Human Bartonellosis. Patients between five and 60 years of age, from endemic areas in Peru,
Revista do Instituto de Medicina Tropical de São Paulo. Publicado em: 2011-06
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17. A dymanical approach to study the immunocompetence and the immunological tolerance of mammals.
In this paper we present an in silico study about immune tolerance, where phase transitions have been observed when antigen dosages were varied in virtual samples. Using a dynamical model to study the behavior of the immune system - presented in a previous edition of the International Symposium on Mathematical and Computational Biology -, we have identified
ANNUAL MEETING OF THE SOCITY FOR MATHEMATICAL BIOLOGY; INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY. Publicado em: 2011
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18. Transcriptional networks reconstruction: identification of genes involved on cattle response to tick Rhipicephalus (Boophilus) microplus infestation.
In tropical countries, losses caused by tick infestation in cattle lead to a great impact on animal production systems. Weight and feed conversion reduction, together with diseases transmitted by the parasite are some of the problems that lead to economic losses of billion dollars a year. In a general way, Bos taurus indicus cattle are less susceptible to in
INTERNATIONAL CONFERENCE OF THE BRAZILIAN ASSOCIATION FOR BIOINFORMATICS AND COMPUTATIONAL BIOLOGY. Publicado em: 2011
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19. Efeito imunomodulatório do resveratrol em células do sistema imune in vitro e na administração via oral de ovalbumina em camundongos / Immunomodulatory effects of resveratrol on immune cells in vitro and in oral administration of ovalbumin in mice.
O resveratrol, um polifenol de origem natural, é descrito como uma substância antiinflamatória, antioxidante, cardioprotetora e anticancerígena. Diversos estudos comprovam a atividade imunomodulatória do resveratrol in vitro e in vivo, estimulando ou diminuindo a secreção de citocinas envolvidas na resposta Th1/Th2. Além do uso em vacinas como adjuva
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2010
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20. CTLA4 CT60 gene polymorphism is not associated with differential susceptibility to pemphigus foliaceus
Pemphigus foliaceus is an organ-specific autoimmune disease characterized by autoantibodies against the extracellular region of desmoglein 1, a protein that mediates intercellular adhesion in desmosomes. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) is a key negative regulator of the T cell immune response, playing an important role in T cell homeosta
Genetics and Molecular Biology. Publicado em: 23/07/2010
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21. Immune cells and oxidative stress in the endotoxin tolerance mouse model
Sepsis is a systemic inflammatory response that can lead to tissue damage and death. In order to increase our understanding of sepsis, experimental models are needed that produce relevant immune and inflammatory responses during a septic event. We describe a lipopolysaccharide tolerance mouse model to characterize the cellular and molecular alterations of im
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-01
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22. The use of stem cells for the treatment of autoimmune diseases
Autoimmune diseases constitute a heterogeneous group of conditions commonly treated with anti-inflammatory, immunosuppressant and immunomodulating drugs, with satisfactory results in most cases. Nevertheless, some patients become resistant to conventional therapy. The use of high doses of drugs in such cases results in the need for bone marrow reconstitution
Publicado em: 2010
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23. Análise de células t regulatórias foxp3+no líquen plano oral
T regulatory cells have the function of controlling immune responses and maintaining self-tolerance. The FoxP3 has been considered the most specific marker for Treg cells. The aiming of this paper was to evaluate the immunoexpression of FoxP3 in the inflammatory infiltrate from oral lichen planus (OLP) and to compare it with the infiltrate in fibrous inflamm
Publicado em: 2010
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24. Células Reguladoras, T CD4+CD25+ e Células NKT na Sepse Grave e Choque Séptico. / The regulatory T cell, CD4+CD25+ and NKT cells in Severe Sepsis and Septic Shock
Sepsis, septic shock and multiple organ failure remain the leading cause of death in the intensive care unit despite significant advances in patient care. However, the mechanisms responsible for this high mortality remain not totally clear, considering that these patients have a generalized immune dysfunction and immunosuppression status. Actually, recent st
Publicado em: 2010