Hsp90 Heat Shock Proteins
Mostrando 1-12 de 126 artigos, teses e dissertações.
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1. The potential of the newly isolated thermotolerant yeast Pichia kudriavzevii RZ8-1 for high-temperature ethanol production
Abstract High potential, thermotolerant, ethanol-producing yeasts were successfully isolated in this study. Based on molecular identification and phylogenetic analysis, the isolated thermotolerant yeasts were clustered in the genera of Pichia kudriavzevii, Candida tropicalis, Candida orthopsilosis, Candida glabrata and Kodamea ohmeri. A comparative study of
Braz. J. Microbiol.. Publicado em: 2018-06
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2. Recombinant 60-kDa heat shock protein from Paracoccidioides brasiliensis: is it a good antigen for serological diagnosis of paracoccidioidomycosis?
Paracoccidioides brasiliensis and P. lutzii are fungi that cause paracoccidioidomycosis (PCM), the most prevalent systemic mycosis in South America. For serological diagnosis, although 43-kDa glycoprotein (gp43) is regarded as highly specific for PCM, the occurrence of false negative reactions in sera from patients infected with P. lutzii suggests that prepa
Braz J Med Biol Res. Publicado em: 03/04/2017
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3. FUNCTIONAL PROTEOMICS OF CIRRHOSIS AND HEPATOCELLULAR CARCINOMA / ProteÃmica Funcional da Cirrose e do Carcinoma Hepatocelular
Introduction. Cancer is the most common given name to a series of molecular and physiological events which result in genetic instability and biochemical imbalance in cells. Among the seven events that drives cell cancer, the role of chronic inflammation and tumor microenvironment in cancer development were highlighted in this work . To experimentally evaluat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/03/2012
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4. Estudos iniciais de ineraçãos da HSP90 através da caracterização funcioanl de um transgênico e biofísica de uma co-chaperona / Insights on Hsp90 chaperone interactions using transgenic and biophysical approaches
Chaperonas moleculares (Heat Shock proteins - HSPs) são componentes chave do sistema de controle de qualidade de proteínas (PQC - Protein Quality Control), que é essencial para a vida, sendo responsável por manter a homeostase proteica e a adequada função de diversas vias. Problemas no processo de enovelamento estão relacionados a doenças degenerativ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/02/2012
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5. Clonagem e caracterização de uma Hsp90 de citrus sinensis potencialmente envolvida no processo infectivo do fitopatógeno Xanthomonas citri / Cloning and characterization of an Hsp90 citrus sinensis potentially involved on the infective process of the plant pathogen Xanthomonas citri
As bactérias patogênicas gram-negativas desenvolveram estratégias sofisticadas para infectar seus hospedeiros, utilizando sistemas de secreção especializados para translocar proteínas de virulência através da membrana das células eucarióticas para o citoplasma. Para que este processo seja eficiente, estas proteínas de virulência devem estar parci
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/08/2011
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6. Characterization of TcSTI-1, a homologue of stress-induced protein-1, in Trypanosoma cruzi
The life cycle of the protozoan Trypanosoma cruzi exposes it to several environmental stresses in its invertebrate and vertebrate hosts. Stress conditions are involved in parasite differentiation, but little is known about the stress response proteins involved. We report here the first characterization of stress-induced protein-1 (STI-1) in T. cruzi (TcSTI-1
Mem. Inst. Oswaldo Cruz. Publicado em: 2011-02
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7. Efeito da solução hipertônica (NaCI 7,5%) no estresse oxidativo e nos processos de morte celular e remodelamento tecidual hepático em pancreatite aguda experimental / Effect of hypertonic saline solution (NaCl 7.5%) on oxidative stress, apoptosis and hepatic tissue remodeling during acute pancreatitis
It has been shown an hepatic injury following pancreatitis and a positive correlation with severity of the disease. Hypertonic Solution (HS) reduced morbidity and mortality in experimental pancreatitis. We hypothesize that hypertonic solution resuscitation of acute pancreatitis (AP) may exert antiinflammatory effects by modulating hepatic oxidative stress, a
Publicado em: 2010
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8. Gentamicin-induced preconditioning of proximal tubular LLC-PK1 cells stimulates nitric oxide production but not the synthesis of heat shock protein
Nephrotoxicity is the main side effect of antibiotics such as gentamicin. Preconditioning has been reported to protect against injuries as ischemia/reperfusion. The objective of the present study was to determine the effect of preconditioning with gentamicin on LLC-PK1 cells. Preconditioning was induced in LLC-PK1 cells by 24-h exposure to 2.0 mM gentamicin
Brazilian Journal of Medical and Biological Research. Publicado em: 22/05/2009
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9. Analise da expressão de chaperonas moleculares em plantas e clonagem, purificação e caracterização inicial das proteinas Hsp100 e Hsp90 de cana-de-açucar / Expression analysis of plant molecular chaperones and cloning, purification and primary charaterization of the proteins Hsp 100 and Hsp90 from sugarcane
Proteins are macromolecules that are vital to the functioning cell, participating in most of the biological reactions as well as structural components. To perform its function, a protein need to achieve its native structure through a process called protein folding. In this context, the molecular chaperone proteins are able to assist in the folding of other p
Publicado em: 2009
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10. Cattle submited with vaccine stress with synthetic immunogenis challenged with Rhipicephalus (Boophilus) microplus and Babesia bovis: immunoistochemistry expression of heat shock proteins and blood biochemical / Bovinos submetidos a estresse vacinal com imunógenos sintéticos e desafiados com Rhipicephalus (Boophilus) microplus e Babesia bovis: expressão imunoistoquímica de proteínas de choque térmico (HSP70 e HSP90) e bioquímica sangüínea
The expression of HSP70 and HSP90 was evaluated through immunoistochemistry studies in bovine inoculated with synthetic peptides SBbo23290 and SBm7462 applied simultaneously, in association or in individual presentation. The animals received three applications with 30 days of interval among them and after challenged with the Babesia bovis strain UFV1 - 9th p
Publicado em: 2007
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11. Efeito da solução hipertônica sobre a expressão de proteínas ativadas por choque térmico (HSPs) e atividade de metaloproteinases (MMPs) teciduais na resposta inflamatória em pancreatite aguda experimental / Effect of the hypertonic solution (HS) in the expression of heat shock proteins (HSPs) and metalloproteinases activity (MMPs) in the lung in experimental pancreatitis
Acute Pancreatitis (AP) is an inflammatory process of the pancreas with variable involvement of other organs and systems. The lungs are the most common distant organs affected by severe acute pancreatitis. The immunomodulatory effects of hypertonic solution (HS) provide potential strategies to attenuate inappropriate inflammatory reactions. This study tested
Publicado em: 2007
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12. Histomorphometry and expression of Heat Shock Proteins (HSP-70) in striated muscles of sedentary rats, trained and submitted or not to exhaustive exercise / Histomorfometria e expressão de proteínas de choque térmico (HSP-70) em músculos estriados de ratos sedentários, treinados e submetidos ou não ao exercício exaustivo
Sabe-se que a natação promove adaptações benéficas aos sistemas cardiovascular e músculo-esquelético. Porém, o exercício físico exaustivo. porém irregular pode induzir lesões musculares. As células sobre várias condições de estresse, sintetizam quantidades significativas de proteínas de choque térmico ou HSP (Heat Shock Proteins ). Algumas
Publicado em: 2007