Hsp90 Heat Shock Proteins
Mostrando 13-24 de 126 artigos, teses e dissertações.
-
13. Aterosclerose na artrite reumatóide e sua associação com auto-imunidade humoral / Atherosclerosis in rheumatoid arthritis and its relationship with humoral autoimmunity
Purpose: Many questions remain unanswered about the causes of accelerated atherosclerosis in patients with inflammatory systemic diseases such as rheumatoid arthritis (RA). Some studies have suggested the role of autoimmunity besides inflammation in the pathogenesis of atherosclerosis in general population and have also discussed the possible association wit
Publicado em: 2007
-
14. Imunolocalização das Heat Shock Proteins (HSPs) 60 e 70 na placenta bovina / Immunolocalization of Heat Shock Proteins (HSPs) 60 e 70 in bovine placenta
Heat Shock Proteins (HSP) can be found in any kind of cell. These proteins are classified according to their molecular weight and their known families include the HSP 27, 60, 70, 90 and 110 kDa. Among these, HSP 60 and 70 are the ones of interest in reproduction. They were known as chaperonines because of their capacity to fold and unfold other proteins into
Publicado em: 2005
-
15. AnÃlise in silico da HSP83 de Leishmania chagasi: implicaÃÃes para antigenicidade e evoluÃÃo
Protozoan parasites belonging to the genus Leishmania are transmitted between mammalian hosts by bloodsucking sand flies and are the etiological agents of the four clinical forms of leishmaniasis: the fatal visceral form, mucocutaneous leishmanasis, cutaneous leishmaniasis and the rare diffuse cutaneous leishmaniasis. Visceral leishmaniases is common in less
Publicado em: 2005
-
16. Anticorpos contra os componentes da placa aterosclerótica beta2-glicoproteína I e proteínas de choque térmico como fatores de risco para isquemia cerebral aguda
Um terço dos casos de isquemia cerebral não apresenta etiologia clara. Uma resposta humoral contra os componentes da placa aterosclerótica beta2-glicoproteína l (beta2-gpl) e proteínas de choque térmico ("heat-shock proteins", Hsp) pode estar envolvida na patogênese do infarto cerebral. Este estudo de caso-controles inclui um perfil completo de antico
Arquivos de Neuro-Psiquiatria. Publicado em: 2003-09
-
17. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70.
Steroid receptors regulate transcription of target genes in vivo and in vitro in a steroid hormone-dependent manner. Unoccupied progesterone receptor exists in the low-salt homogenates of target cells as a functionally inactive 8 to 10S complex with several nonreceptor components such as two molecules of 90-kDa heat shock protein (hsp90), a 70-kDa heat shock
-
18. Targeting HSP90 for cancer therapy
Heat-shock proteins (HSPs) are molecular chaperones that regulate protein folding to ensure correct conformation and translocation and to avoid protein aggregation. Heat-shock proteins are increased in many solid tumours and haematological malignancies. Many oncogenic proteins responsible for the transformation of cells to cancerous forms are client proteins
Nature Publishing Group.
-
19. Heat Shock Response in the Thermophilic Enteric Yeast Arxiozyma telluris
Heat stress tolerance was examined in the thermophilic enteric yeast Arxiozyma telluris. Heat shock acquisition of thermotolerance and synthesis of heat shock proteins hsp 104, hsp 90, hsp 70, and hsp 60 were induced by a mild heat shock at temperatures from 35 to 40°C for 30 min. The results demonstrate that a yeast which occupies a specialized ecological
American Society for Microbiology.
-
20. Isolation of Hsp90 mutants by screening for decreased steroid receptor function.
The 90-kDa heat shock protein Hsp90 represents a highly conserved strongly expressed gene family; in Saccharomyces cerevisiae, Hsp90 proteins are essential for cell viability. Hsp90 interacts with certain cellular proteins, including steroid hormone receptors, tyrosine and serine/threonine kinases, and other heat shock proteins, but its biological functions
-
21. Heat shock-regulated production of Escherichia coli beta-galactosidase in Saccharomyces cerevisiae.
The HSP90 gene of the yeast Saccharomyces cerevisiae encodes a heat shock-inducible protein with an Mr of 90,000 (hsp90) and unknown function. We fused DNA fragments of a known sequence (namely, either end of a 1.4-kilobase EcoRI fragment which contains the S. cerevisiae TRP1 gene) to an EcoRI site within the coding sequence of the HSP90 gene. When these fus
-
22. HEAT SHOCK PROTEIN 90C Is a Bona Fide Hsp90 That Interacts with Plastidic HSP70B in Chlamydomonas reinhardtii1
We report on the molecular and biochemical characterization of HEAT SHOCK PROTEIN 90C (HSP90C), one of the three Hsp90 chaperones encoded by the Chlamydomonas reinhardtii genome. Fractionation experiments indicate that HSP90C is a plastidic protein. In the chloroplast, HSP90C was localized to the soluble stroma fraction, but also to thylakoids and low-densit
American Society of Plant Biologists.
-
23. Murine 86-kDa heat shock protein gene and promoter
The class of 90 kDa heat shock proteins (Hsp90) is among the most abundant heat shock proteins (Hsps) in eukaryotic cells. In vertebrates, Hsp90 is encoded by two distinct gene families giving rise to products of 84 and 86 kDa. In mice the expression of these two genes, hsp84 and hsp86, vary with respect to each other in responses to stress, and also in resp
Cell Stress Society International.
-
24. Selective activation of human heat shock gene transcription by nitrosourea antitumor drugs mediated by isocyanate-induced damage and activation of heat shock transcription factor.
Treatment of cultured human tumor cells with the chloroethylnitrosourea antitumor drug 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) selectively induces transcription and protein synthesis of a subset of the human heat shock or stress-induced genes (HSP90 and HSP70) with little effect on other stress genes or on expression of the c-fos, c-myc, or beta-actin ge