Gonadal Disorders
Mostrando 1-12 de 20 artigos, teses e dissertações.
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1. Linear and Nonlinear Heart Rate Variability Analysis in Gonadal Dysgenesis (Swyer Syndrome): A Case Report
Abstract Swyer syndrome is one of the disorders of sexual differentiation. Previous studies have demonstrated increased sympathetic activity with heart rate variability (HRV) analysis with decreasing estradiol levels. One patient presented a pure 46, XY gonadal dysgenesis with female phenotype. Cardiac autonomic modulation was assessed through HRV analysis w
Int. J. Cardiovasc. Sci.. Publicado em: 2021-08
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2. Ten cases with 46,XX testicular disorder of sex development: single center experience
ABSTRACT Objective To present clinical, chromosomal and hormonal features of ten cases with SRY-positive 46,XX testicular disorder of sex development who were admitted to our infertility clinic. Cases and Methods Records of the cases who were admitted to our infertility clinic between 2004 and 2015 were investigated. Ten 46,XX testicular disorder of sex
Int. braz j urol.. Publicado em: 2017-08
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3. Clinical profile of 93 cases of 46, XY disorders of sexual development in a referral center
ABSTRACT The term DSD refers to disorders that affect the normal process of sexual development causing disagreement between chromosomal, gonadal and phenotypic sex, and this study aimed to describe the clinical profile of a group with DSD 46, XY joined on DSD Clinic of Hospital of Salvador, Bahia Clinics. It was a retrospective study of medical records of su
Int. braz j urol.. Publicado em: 2015-10
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4. Pesquisa de mutações no gene DMRT1 em pacientes portadores de distúrbios do desenvolvimento sexual (DDS) 46,XY por anormalidades gonadais / Search of mutation on DMRT1 gene in patients with 46,XY disorders of sex development (DSD) by gonads abnormalities
Introdução: O gene DMRT1 é um fator muito importante, o qual induz a determinação sexual masculina. Estudos mais recentes têm demonstrado que o Dmrt1 possui um papel significante no desenvolvimento ovariano. Deleções restritas ao gene DMRT1 têm sido raramente identificadas em pacientes com disgenesia gonadal (DG) sem outras características sindrôm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/09/2012
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5. Pesquisa de mutações nos genes FGF9 e FGFR2 em pacientes portadores de distúrbios do desenvolvimento sexual 46,XY por anormalidades no desenvolvimento gonadal / Search for mutations on FGF9 and FGFR2 genes in patients with 46,XY disorders of sexual development by gonadal abnormalities
Introdução: Várias evidências em estudos de animais knockout sugerem a efetiva participação dos genes Fgf9-Fgfr2 no processo de determinação testicular. Animais XY knockout para os genes Fgf9 e Fgfr2 apresentam reversão sexual como consequência da alteração na cascata de eventos masculinizantes nas gônadas fetais. Até o momento, mutações inat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2012
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6. Influência dos hormônios sexuais na analgesia induzida pelo estresse / Influence of sex hormones in stress-induced analgesia
Temporomandibular disorders comprehend a variable group of conditions which result in joint and/or muscle pain and contribute to the development of acute pains, being more prevalent in women than men, especially during the reproductive period. They involve the muscles of mastication and temporomandibular joint (ATM), being usually associated with inflammator
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/07/2011
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7. Influence of the feminine hormonal fluctuation on bite force and masticatory performance in patients with temporomandibular disorders / Influência da flutuação hormonal feminina na força de mordida e performance mastigatória de pacientes portadoras de desordens temporomandibulares
A maior prevalência de desordens temporomandibulares (DTMs) ocorre especialmente em mulheres durante a fase reprodutiva, sugerindo uma possível influência dos hormônios reprodutivos na etiologia destas desordens. O objetivo do presente trabalho foi avaliar a possível influência das flutuações hormonais ocorridas durante o ciclo menstrual, sobre a for
Publicado em: 2010
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8. Clinical and molecular analysis of patients with disorders of gonadal development / Análise clínica e molecular de pacientes com distúrbios do desenvolvimento gonadal
Introdução: O termo distúrbios do desenvolvimento gonadal (DDG) inclui condições congênitas nas quais o desenvolvimento gonadal é atípico. Estudos feitos em camundongos observaram que alguns genes como o Cbx2 e o Tcf21 interferem na fase inicial do desenvolvimento gonadal, afetando tanto gônadas XX quanto XY. O gene Dhh, por sua vez, codifica o fato
Publicado em: 2009
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9. Avaliação da disfunção gonadal e tratamento com metformina do hipogonadismo masculino associado à síndrome metabólica
The Metabolic syndrome is among the most common metabolic disorders nowadays. In the gonadotrophic axis, it can be associated with the state of male hypogonadism. The objectives. were evaluate the incidence of hypogonadism in males with metabolic syndrome and its correlation with insulin, then evaluate the effect of the treatment with an insulin sensitizer (
Publicado em: 2008
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10. Implicações psicologicas da (in)fertilidade em mulheres com fenotipo feminino e genotipo discordante
The present study was aimed at assessing the psychological characteristics and experiences of individuals with sex differentiation disorders, represented by phenotypic females with a 46,XY karyotype. Eight participants were selected, ages ranging from 22 to 44 years, who presented primary amenorrhea and sterility, lack of development of secondary sexual char
Publicado em: 2006
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11. Clinical and molecular analysis of human reproductive disorders in Brazilian patients
Several genes that influence the development and function of the hypothalamic-pituitary-gonadal-axis (HPG) have been identified. These genes encode an array of transcription factors, matrix proteins, hormones, receptors, and enzymes that are expressed at multiple levels of the HPG. We report the experience of a single Endocrinology Unit in the identification
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-01
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12. Avaliação molecular do gene WT1 em pacientes pre-puberes com disgenesia gonadal parcial
Male sex detennination in humans depends on the presence of one Y chromosome, which by SRY gene expression leads to the differentiation of the gonadal primordia into testes. Other genes are involved in male sex determination and differentiation, such as the WTl, that codes a "zinc finger" transcription factor essential to the gonadal and renal development in
Publicado em: 2004