Entails And Development
Mostrando 13-24 de 26 artigos, teses e dissertações.
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13. Da ex-sociedade de caranguejos e dos seus irmÃos de leite aos "pombos sem asas" : complexidades ambientais em assentamentos urbanos do Recife sob uma perspectiva antropolÃgica
The present study results from the observed fact that human populations have managed to survive in complex environments, degraded milieux in terms of socioenvironmental development, which entails the deterioration of life quality. The study sets out to analyze, from an anthropological framework, the socioenvironmental problems in two spontaneous urban settle
Publicado em: 2004
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14. Proposta de capacitação para profissionais do programa saúde da família da Região do Médio Vale do Itajaí: um estudo de caso com foco nos tipos cognitivos da equipe de enfermagem
The present work treats of the professionals training that integrate the nursing teams of the Program Health of Family, in way to contribute for the improvement in the model of basic attention of the health. Considering the context of the regional development, the study is centered in the area of the Medium Valley of Itajaí (MVI), that is characterized by t
Publicado em: 2002
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15. PRODUCT DESIGN IN THE CONTEXT OF THE SOCIAL NEEDS IN LESS INDUSTRIALISED ECONOMIES
This thesis is related to the subject of technical innovation, specifically to the activity of design in microenterprises operating in less industrialised economies. Design here is understood as a process, which is not the sole domain of formally trained categories such as engineers, architects or industrial designers. The professional boundary discussion in
Publicado em: 1996
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16. Light Control of Arabidopsis Development Entails Coordinated Regulation of Genome Expression and Cellular PathwaysW⃞
An expressed sequence tag–based microarray was used to profile genome expression underlying light control of Arabidopsis development. Qualitatively similar gene expression profiles were observed among seedlings grown in different light qualities, including far-red, red, and blue light, which are mediated primarily by phytochrome A, phytochrome B, and the c
American Society of Plant Biologists.
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17. Mitochondrial Development during Life Cycle Differentiation of African Trypanosomes: Evidence for a Kinetoplast-dependent Differentiation Control Point
Life cycle differentiation of African trypanosomes entails developmental regulation of mitochondrial activity. This requires regulation of the nuclear genome and the kinetoplast, the trypanosome's unusual mitochondrial genome. To investigate the potential cross talk between the nuclear and mitochondrial genome during the events of differentiation, we have 1)
The American Society for Cell Biology.
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18. Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel
Defects in polycystin-2, a ubiquitous transmembrane glycoprotein of unknown function, is a major cause of autosomal dominant polycystic kidney disease (ADPKD), whose manifestation entails the development of fluid-filled cysts in target organs. Here, we demonstrate that polycystin-2 is present in term human syncytiotrophoblast, where it behaves as a nons
The National Academy of Sciences.
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19. Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C.
The immunopathogenesis of autoimmune insulin-dependent diabetes in NOD mice entails defects in the development of macrophages (M phi s) from hematopoietic precursors. The present study analyzes the cellular and molecular basis underlying our previous finding that the Mø growth factor colony-stimulating factor 1 (CSF-1) promotes a reduced level of promonocyt
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20. Active barnase variants with completely random hydrophobic cores.
The central structural feature of natural proteins is a tightly packed and highly ordered hydrophobic core. If some measure of exquisite, native-like core packing is necessary for enzymatic function, this would constitute a significant obstacle to the development of novel enzymes, either by design or by natural or experimental evolution. To test the minimum
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21. Effect of Environmental pH on Morphological Development of Candida albicans Is Mediated via the PacC-Related Transcription Factor Encoded by PRR2
The ability to respond to ambient pH is critical to the growth and virulence of the fungal pathogen Candida albicans. This response entails the differential expression of several genes affecting morphogenesis. To investigate the mechanism of pH-dependent gene expression, the C. albicans homolog of pacC, designated PRR2 (for pH response regulator), was identi
American Society for Microbiology.
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22. Suppression of mammary epithelial cell differentiation by the helix-loop-helix protein Id-1.
Cell proliferation and differentiation are precisely coordinated during the development and maturation of the mammary gland, and this balance invariably is disrupted during carcinogenesis. Little is known about the cell-specific transcription factors that regulate these processes in the mammary gland. The mouse mammary epithelial cell line SCp2 grows well un
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23. Next-generation SELEX identifies sequence and structural determinants of splicing factor binding in human pre-mRNA sequence
Many splicing factors interact with both mRNA and pre-mRNA. The identification of these interactions has been greatly improved by the development of in vivo cross-linking immunoprecipitation. However, the output carries a strong sampling bias in favor of RNPs that form on more abundant RNA species like mRNA. We have developed a novel in vitro approach for su
Cold Spring Harbor Laboratory Press.
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24. TFIIB-directed transcriptional activation by the orphan nuclear receptor hepatocyte nuclear factor 4.
The orphan nuclear receptor hepatocyte nuclear factor 4 (HNF-4) is required for development and maintenance of the liver phenotype. HNF-4 activates several hepatocyte-specific genes, including the gene encoding apolipoprotein AI (apoAI), the major protein component of plasma high-density lipoprotein. The apoAI gene is activated by HNF-4 through a nuclear rec