Domesticated Transposase
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Estudo de dois grupos de elementos de cana-de-açúcar homológos à superfamília hAT de transposons / Studies on hAT-like transposases in sugarcane superfamily
Transposable elements (TEs) are mobile genetic sequences. Their mutagenic capacity makes them important sources of variation in the genomes. These elements have another important evolutionary role as donors of functional protein domains in the formation of new genes. 276 cDNA clones homologous to TEs were previously identified in the Brazilian Sugarcane Expr
Publicado em: 2007
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2. PiggyMac, a domesticated piggyBac transposase involved in programmed genome rearrangements in the ciliate Paramecium tetraurelia
Programmed genome rearrangements drive functional gene assembly in ciliates during the development of the somatic macronucleus. The elimination of germline sequences is directed by noncoding RNAs and is initiated by DNA double-strand breaks, but the enzymes responsible for DNA cleavage have not been identified. We show here that PiggyMac (Pgm), a domesticate
Cold Spring Harbor Laboratory Press.
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3. Subtraction by addition: domesticated transposases in programmed DNA elimination
The ciliate Paramecium tetraurelia must eliminate ∼60,000 short sequences from its genome to generate uninterrupted coding sequences in its somatic macronucleus. In this issue of Genes & Development, Baudry and colleagues (pp. 2478–2483) identify the protein that excises these noncoding sequences: a domesticated piggyBac transposase that has been adapted
Cold Spring Harbor Laboratory Press.