Domain Condensation
Mostrando 1-12 de 87 artigos, teses e dissertações.
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1. Molecular And 3D-Structural Characterization Of Fructose-1,6-Bisphosphate Aldolase Derived From Metroxylon Sagu
ABSTRACT Fructose-1,6-bisphosphate aldolase (FBAld) is an enzyme that catalyzes the cleavage of D-fructose-1,6-phosphate (FBP) to D-glyceraldehyde-3-phosphate (G3P) and dihydroxyacetone phosphate (DHAP), and plays vital role in glycolysis and gluconeogenesis. However, molecular characterization and functional roles of FBAld remain unknown in sago palm. Here
Braz. arch. biol. technol.. Publicado em: 22/06/2017
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2. A time-domain finite element model reduction method for viscoelastic linear and nonlinear systems
AbstractMany authors have shown that the effective design of viscoelastic systems can be conveniently carried out by using modern mathematical models to represent the frequency- and temperature-dependent behavior of viscoelastic materials. However, in the quest for design procedures of real-word engineering structures, the large number of exact evaluations o
Lat. Am. j. solids struct.. Publicado em: 2015-06
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3. Desenvolvimento de vetores não virais para entrega gênica baseados na cadeia leve de dineína Rp3 = : Development of non viral vectors for gene delivery based on dynein light chain Rp3 / Development of non viral vectors for gene delivery based on dynein light chain Rp3
Gene delivery is a promising technique with great medical potential that consists in the introduction of exogenous nucleic acids, and can be applied for gene therapy as well as DNA vaccination. However, its use is still limited by the lack of an ideal delivery vector, which is both safe and efficient. Although much more effective, viral vectors still raise s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2012
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4. Tumor cytotoxicity of leucurolysin-B, a P-III snake venom metalloproteinase from Bothrops leucurus
Although it has been demonstrated that venoms and toxins from some snakes are able to influence the growth of tumor cells, few antitumoral compounds from Bothrops leucurus venom have been characterized. Leucurolysin-B (leuc-B) is a metalloproteinase class P-III isolated from B. leucurus which possesses an ECD-disintegrin domain. Both ECD-disentegrin and RGD-
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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5. Childhood and old age: pathways in Manuelzão e Miguilim. / A infância e a velhice: percursos em Manuelzão e Miguilim
This work is a study of the novellas Campo geral and Uma estória de amor (Festa de Manuelzão), by Guimarães Rosa, that compose the book Manuelzão e Miguilim, one of the three volumes of Corpo de baile, which the author partitioned in the third edition. The dissertation seeks to articulate aspects of psychoanalytic theory, especially those stemming from t
Publicado em: 2010
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6. Development of numerical models for interaction problems of two-dimensional domain analysis / Desenvolvimento de modelos numéricos para análise de problemas de interação de domínios bidimensionais
Neste trabalho foi desenvolvida uma formulação para análise de sólidos bidimensionais constituídos por multiregiões utilizando-se do método dos elementos de contorno para análise linear e não linear. Para o caso de análise linear foi estudado o caso de regiões constituídas por sub-regiões de diferentes características mecânicas, utilizando-se
Publicado em: 2007
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7. Aircraft loads assessment for windmilling sustained engine imbalance condition.
The failure of an aircraft engine fan blade produces an unbalanced rotor condition. Even after the engine is shutdown, the aerodynamic forces may keep the rotors running during the remainder of the flight. This condition can induce significant vibratory loads throughout the airframe that may damage the airframe structure and critical equipments and also affe
Publicado em: 2005
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8. Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation
MST1, mammalian STE20-like kinase 1, is a serine/threonine kinase that is cleaved and activated by caspases during apoptosis. MST1 is capable of inducing apoptotic morphological changes such as chromatin condensation upon overexpression. In this study, we show that MST1 contains two functional nuclear export signals (NESs) in the C-terminal domain, which is
The National Academy of Sciences.
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9. Molecular mechanism for silencing virally transduced genes involves histone deacetylation and chromatin condensation
Virally transduced genes are often silenced after integration into the host genome. Chromatin immunoprecipitation and nuclease sensitivity experiments now demonstrate that silencing of the transgene is characterized by deacetylation of histone H4 lysines and chromatin condensation. Trichostatin A treatment results in dramatic reactivation of gene expression
The National Academy of Sciences.
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10. Condensation by DNA looping facilitates transfer of large DNA molecules into mammalian cells
Experimental studies of complete mammalian genes and other genetic domains are impeded by the difficulty of introducing large DNA molecules into cells in culture. Previously we have shown that GST–Z2, a protein that contains three zinc fingers and a proline-rich multimerization domain from the polydactyl zinc finger protein RIP60 fused to glutathione S
Oxford University Press.
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11. Unifying features in protein-folding mechanisms
We compare the folding of representative members of a protein superfamily by experiment and simulation to investigate common features in folding mechanisms. The homeodomain superfamily of three-helical, single-domain proteins exhibits a spectrum of folding processes that spans the complete transition from concurrent secondary and tertiary structure formation
National Academy of Sciences.
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12. Glom Is a Novel Mitochondrial DNA Packaging Protein in Physarum polycephalum and Causes Intense Chromatin Condensation without Suppressing DNA Functions
Mitochondrial DNA (mtDNA) is packed into highly organized structures called mitochondrial nucleoids (mt-nucleoids). To understand the organization of mtDNA and the overall regulation of its genetic activity within the mt-nucleoids, we identified and characterized a novel mtDNA packaging protein, termed Glom (a protein inducing agglomeration of mitochondrial
The American Society for Cell Biology.