Cyclodepsipeptides
Mostrando 1-6 de 6 artigos, teses e dissertações.
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1. Larvicidal Activity of Beauveria bassiana Extracts against Aedes aegypti and Identification of Beauvericins
Beauveria bassiana is an entomopathogenic fungus that has been well known for its capacity to act as biopesticide on various disease vectors. The analysis of organic extracts of strains CG71 and UNI40 led to identification of cyclodepsipeptides beauvericin, beauvericin A or F, beauvericin E and bassianolide by ultra-high pressure liquid chromatography-high r
J. Braz. Chem. Soc.. Publicado em: 2017-06
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2. Copper and Manganese Cations Alter Secondary Metabolism in the Fungus Penicillium brasilianum
The fungus Penicillium brasilianum LaBioMMi 136 was isolated as an endophyte from Melia azedarach and has shown to be a prominent producer of great diversity of secondary metabolites, although it does not express some biosynthetic routes to other natural compounds found in Penicillium genera. The present study aimed at the diversification of P. brasilianum s
J. Braz. Chem. Soc.. Publicado em: 2016-08
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3. A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina
Extracts obtained from 57 marine-derived fungal strains were analyzed by HPLC-PDA, TLC and ¹H NMR. The analyses showed that the growth conditions affected the chemical profile of crude extracts. Furthermore, the majority of fungal strains which produced either bioactive of chemically distinctive crude extracts have been isolated from sediments or marine alg
Química Nova. Publicado em: 2008
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4. "Metabólitos secundários biologicamente ativos isolados de esponjas marinhas e do fungo Beauveria felina de origem marinha" / "Biologically active secondary metabolites from Marine Sponges and from the Marine-Derived fungus Beauveria felina"
In this work we report the chemical investigation of bioactive crude extracts obtained from four sponges and two fungal strains of marine origin. The crude extracts of three sponges species (Petromica ciocalyptoides, Topsentia ophiraphidites and Callyspongia sp.) displayed inhibitory activity towards the enzyme adenine fosforribosyl transferase of Leishmania
Publicado em: 2007
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5. Antiatherogenic activity of fungal beauveriolides, inhibitors of lipid droplet accumulation in macrophages
Beauveriolides I and III, isolated from the culture broth of fungal Beauveria sp. FO-6979, showed potent inhibitory activity of lipid droplet accumulation in primary mouse peritoneal macrophages. The cellular molecular target of this inhibitory activity was studied in macrophages. Beauveriolides I and III strongly inhibited the cholesteryl ester (CE) synthes
National Academy of Sciences.
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6. Total synthesis of the marine cyanobacterial cyclodepsipeptide apratoxin A
A total synthesis of apratoxin A was developed. Apratoxin A, isolated from Lyngbya spp. cyanobacteria, is representative of a growing class of marine cyanobacterial cyclodepsipeptides wherein discrete polypeptide and polyketide domains are merged by ester and amide or amide-derived linkages. In the apratoxins, the N terminus of the peptide domain [(Pro)-(N-M
National Academy of Sciences.