Calcium Channel Blockers
Mostrando 13-24 de 189 artigos, teses e dissertações.
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13. Investigation into in vitro anti-leishmanial combinations of calcium channel blockers and current anti-leishmanial drugs
The need for drug combinations to treat visceral leishmaniasis (VL) arose because of resistance to antimonials, the toxicity of current treatments and the length of the course of therapy. Calcium channel blockers (CCBs) have shown anti-leishmanial activity; therefore their use in combination with standard drugs could provide new alternatives for the treatmen
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-12
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14. Efeito da tansulosina e do nifedipino na eliminação de fragmentos após litotripsia extracorpórea por ondas de choque em pacientes com cálculos renais: estudo prospectivo, duplo-cego e randomizado / Effect of tamsulosin and nifedipine on the clearance of fragments after extracorporeal shock waves lithotripsy in patients with kidney stones - a prospective, double-blind and randomized study
Purpose: We evaluated the effects of the adjuvant use of tamsulosin and nifedipine after extracorporeal shock wave lithotripsy (SWL) for 5-20 mm kidney stones. Materials and Methods: We conducted a randomized double-blind trial involving 136 patients with radiopaque kidney stones between 2006 and 2009. Patients were divided into three groups to receive daily
Publicado em: 2011
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15. EFEITOS CARDIOVASCULARES DO ÓLEO ESSENCIAL DE LIPPIA ALBA (MILL) N.E. BROWN. (ERVA CIDREIRA BRASILEIRA) EM RATOS. / CARDIOVASCULAR EFFECTS OF THE ESSENTIAL OIL LIPPIA ALBA (MILL) N.E. BROWN (ERVA CIDREIRA BRASILEIRA) IN RATS.
A Lippia alba (Mill.) N.E. Brown (VERBENACEAE), conhecida popularmente como Erva Cidreira Brasileira, é uma das plantas mais utilizadas na medicina popular brasileira, inclusive para o tratamento da hipertensão arterial. Este estudo buscou investigar os efeitos cardiovasculares do óleo essencial de Lippia alba (OELA) em ratos. Para registro dos parâmetro
Publicado em: 2011
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16. Effect of felodipine on myocardial and renal injury induced by aldosterone-high salt hypertension in uninephrectomized rats
It has been recently shown that calcium channel blockers might have a protective effect on cardiac fibrogenesis induced by aldosterone. The objective of this study was to evaluate the protective effect of felodipine, a dihydropyridine calcium channel blocker, against heart and kidney damage caused by aldosterone-high sodium intake in uninephrectomized rats.
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-05
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17. AUMENTO GENGIVAL ASSOCIADO À CICLOSPORINA EM TRANSPLANTADOS RENAIS NO HUSM
Background: Gingival enlargement (GE) is a frequent finding in cyclosporin users. The mechanisms of this association are not totally known and point out to a multifactorial model, with dose and associations with calcium channel blockers. Novel immunosuppression protocols are adjusting for drugs and dosages. Aim: This study aimed at investigating the prevalen
Publicado em: 2010
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18. Efeitos pré e pós sinápticos dos inibidores da acetilcolinesterase na neurotransmissão em musculatura lisa.
Justification: The present work considers the effects of new inhibitors of acetylcholinesterase (AChE) on the reactivity and neurotransmission in rats and mice. The new anticholinesterase compounds, ITH12118 and ITH12117, have an hybrid stucture, derived from the molecule of of the anticholinesterase Tacrine and the 1,4 dihydropyridine nimodipine, a blocker
Publicado em: 2010
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19. Avaliação dos efeitos induzidos pelo 2-Nitrato-1, 3-Dibutoxipropano (NDBP) sobre o sistema cardiovascular de ratos normotensos - abordagens en vivo e in vitro
Organic nitrates are nitric oxide (NO) donors used in the treatment of cardiovascular diseases mimicking the role of endogenous NO. This study evaluated organic nitrates newly synthesized from glycerin, which cardiovascular actions had not yet been investigated. Therefore, the cardiovascular effects produced by organic nitrates derived from glycerin: 2-nitra
Publicado em: 2010
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20. Participação Do Cálcio Citosólico Sobre A Ação Espasmolítica Do Ácido Ent-7a-Acetoxitraquiloban-18-Óico E De Seu Derivado Hidroxilado Em Íleo Isolado De Cobaia / Partipation of cytosolic calcium in spasmolytic action of ent-7a-acetoxytrachyloban-18-oic acid and its hidroxylated derivated on guinea-pig ileum
From the stem bark of Xylopia langsdorfiana A. St.-Hil. &Tul. (Annonaceae), popularly known as pimenteria da terra, was isolated the diterpene ent-7-α-acetoxytrachyloban-18-oic acid (trachylobane-360) from which it was made a structural modification in which the acetoxy group was substituted by hydroxy generating the ent-7a-hidroxitrachyloban-18-oic aci
Publicado em: 2010
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21. Uso de anti-hipertensivos e hipoglicemiantes por idosos, em Belo Horizonte, MG
Introduction: Changes in the epidemiological profile, coupled with demographic transition, the improvement in quality of life and technological advances, are characteristics of the aging phenomenon of Brazilian population, where are predominant the cardiovascular diseases. Among the main risk factors are arterial hypertension (HA) and diabetes mellitus (DM).
Publicado em: 2010
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22. Efeito neuroprotetor do anestésico propofol em fatias de hipocampo de ratos submetidos à isquemia cerebral in vitro
There are several studies that propofol, an intravenous anesthetic, reduces neuronal injury due to brain ischemia. However, the results of such neuroprotection in ischemic models have been conflicting, both in vitro and in vivo studies. In addition, the mechanisms involved in propofol neuroprotection have not been clarified. The aim of the present study was
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/09/2009
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23. Effects of the calcium channel blocker amlodipine on bone healing of a surgical defect in the mandibular ramus of rats / Efeitos do bloqueador de canais de cálcio amlodipina na reparação óssea em defeito cirúrgico no ramo mandibular de ratos
Os anti-hipertensivos bloqueadores de canais de cálcio, por interferirem no transporte de cálcio através das membranas celulares, podem afetar muitos processos metabólicos, incluindo o metabolismo ósseo. O objetivo deste estudo foi avaliar, de forma radiográfica, histológica e bioquímica, os efeitos do bloqueador de canais de cálcio amlodipina no pr
Publicado em: 2009
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24. Prevenção da nefrotoxicidade por contraste em pacientes oncológicos: comparação de hidratação com solução a base de cloreto de sódio e bicarbonato de sódio / Prevention of contrast-induced nephropathy in oncology patients. Hydration with 0.9% sodium chloride compared to sodium bicarbonate
The incidence of contrast nephropathy has increased simultaneously to the augment of the use of diagnostic and interventional imaging procedures. Unfortunately, a large number of physicians do not know its existence and even when so do, sometimes do not do not know the risk factors associated to its development. The incidence of contrast nephropathy in the g
Publicado em: 2009