Butyrylcholinesterase
Mostrando 13-24 de 69 artigos, teses e dissertações.
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13. A New Biflavonoid from
Schinopsis brasiliensis (Anacardiaceae)Phytochemical investigation of the MeOH extract of Schinopsis brasiliensis Engl. stems led to the isolation of the new biflavanone (2R*,3R*,2''R*,3''R*)-7-hydroxy-4'-methoxy-flavanone- (3→3'')-3''',7''-dihydroxy-4'''-methoxy-flavanone and 4,2',4'-trihydroxychalcone-(3→O→4'')- 2''',4'''-dihydroxychalcone, whereas methyl gallate, gallic acid, (6R,9R)-
J. Braz. Chem. Soc.. Publicado em: 2015-07
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14. Gestational diabetes mellitus (GDM) decreases butyrylcholinesterase (BChE) activity and changes its relationship with lipids
Many conditions interfere with butyrylcholinesterase (BChE) activity, e.g., pregnancy or presence of the BCHE gene variant -116A can decrease activity whereas obesity and types I and II diabetes mellitus can increase activity. In this study, we examined BChE activity, -116A and 1615A BCHE gene variants, and anthropometric and biochemical variables associated
Genet. Mol. Biol.. Publicado em: 2014
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15. Influence of obstructive sleep apnea on serum butyrylcholinesterase activity and ischemia-modified albumin levels
OBJECTIVE: To investigate the effect of obstructive sleep apnea and continuous positive airway pressure treatment on serum butyrylcholinesterase activity and ischemia-modified albumin levels. METHODS: Thirty-two patients with obstructive sleep apnea and 30 age- and sex-matched controls were enrolled and underwent a diagnostic polysomnogram. The serum butyry
Clinics. Publicado em: 2013-07
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16. 2-Phenitidine derivatives as suitable inhibitors of butyrylcholinesterase
Este trabalho apresenta a síntese de uma série de derivados da 2-fenetidina N-substituídos. Primeiro, a reação da 2-fenetidina (1) com cloreto de benzenossulfonila (2) conduziu à N-(2-etoxifenil)benzenossulfonamida (3) que, após tratamento com hidreto de sódio e haletos de alquila (4a-g), originou novas sulfonamidas (5a-g). Em segundo lugar, a reaç�
Braz. J. Pharm. Sci.. Publicado em: 2013-03
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17. Variantes genéticas de risco para a dependência de crack/cocaína: estudo de associação do tipo gene candidato e epistasia / Genetic risk variants for crack/cocaine dependence:gene candidate association study and epistasis
O uso da cocaína e do crack tornou-se um problema de saúde pública importante no Brasil por conta de prejuízos significativos do ponto de vista médico, psicológico e social que ele acarreta. Estudos de gêmeos e, em famílias, sugerem que a dependência de cocaína é uma doença complexa, com participação importante de fatores genéticos. Os estudos
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/03/2012
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18. ATIVIDADE DE ECTOENZIMAS E DE COLINESTERASES E BIOMARCADORES DE ESTRESSE OXIDATIVO EM PACIENTES COM CÂNCER DE PULMÃO / ACTIVITY OF ECTOENZIMAS AND CHOLINESTERASES AND OXIDATIVE STRESS BIOMARKERS IN PATIENTS WITH LUNG CANCER
Lung cancer has become one of the most commonly diagnosed neoplastic diseases, as well as one of the most lethal worldwide, characterized, therefore, as a public health problem. This spread of lung cancer in the world population, which is clearly seen in statistics, is closely related to smoking, and smoking is considered one of the main risk factors that le
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2012
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19. Effects of physical exercise on butyrylcholinesterase in obese adolescents
The aim of the present study was to evaluate the effect of a 12 week program of physical exercise (PE) on butyrylcholinesterase (BChE) in obese adolescents. This study compared obese adolescents (N = 54) before and after PE, regarding the relative intensity (RI) and activity of different molecular forms (G1, G2, G4 and G1-ALB) of BChE found in plasma. Waist
Genet. Mol. Biol.. Publicado em: 09/10/2012
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20. Metabolic and biological prospecting of Coreopsis tinctoria
Coreopsis tinctoria Nutt., Asteraceae, flowering tops infusion has been traditionally used in many countries to control hyperglycaemia. In this work we report for the first time fatty acids and volatile compounds in this species. Fifteen fatty acids and sixteen volatile compounds were determined by GC-ITMS, being saturated fatty acids and monoterpenes the ma
Revista Brasileira de Farmacognosia. Publicado em: 05/12/2011
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21. Augmentation of catecholamine release elicited by an Eugenia punicifolia extract in chromaffin cells
Plant extracts of Eugenia punicifolia (Kunth) DC., Myrtaceae, are used in Amazon region of Brazil to treat diarrhea and stomach disturbances, and as hypoglycemic medicine. We have recently shown that an aqueous extract of E. punicifolia augmented cholinergic neurotransmission in a rat phrenic nerve-diaphragm preparation. In this study, we investigated the ef
Revista Brasileira de Farmacognosia. Publicado em: 14/10/2011
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22. Analysis of Amaryllidaceae alkaloids from Zephyranthes grandiflora by GC/MS and their cholinesterase activity
Amaryllidaceae are known as ornamental plants, furthermore some species of this family contain galanthamine, an acetylcholinesterase inhibitor approved for the treatment of Alzheimer's disease, and other alkaloids with interesting pharmacological activity. The chemical composition of alkaloids from Zephyranthes grandiflora Lindl. was analyzed by GC/MS. Seven
Revista Brasileira de Farmacognosia. Publicado em: 20/05/2011
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23. Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes
Ghrelin coded by the GHRL gene is related to weight-gain, its deactivation possibly depending on its hydrolyzation by butyrylcholinesterase (BChE) encoded by the BCHE gene, an enzyme already associated with the body mass index (BMI). The aim was to search for relationships between SNPs of the GHRL and BCHE genes with BChE activity, BMI and obesity in 144 obe
Genetics and Molecular Biology. Publicado em: 2011
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24. Biochemical and genetic analysis of butyrylcholinesterase (BChE) in a family, due to prolonged neuromuscular blockade after the use of succinylcholine
Butyrylcholinesterase (BChE) is a plasma enzyme that catalyzes the hydrolysis of choline esters, including the muscle-relaxant succinylcholine and mivacurium. Patients who present sustained neuromuscular blockade after using succinylcholine usually carry BChE variants with reduced enzyme activity or an acquired BChE deficiency. We report here the molecular b
Genetics and Molecular Biology. Publicado em: 2011