Biglycan
Mostrando 1-12 de 16 artigos, teses e dissertações.
-
1. Immunohistochemical expression of biglycan and decorin in the pulp tissue of human primary teeth during resorption
Primary teeth are interesting models that can be used to study physiological and pathological processes involving cells and extracellular matrices in hard and soft tissues. This study investigated the expression and distribution of biglycan and decorin-the non-collagenous components of the extracellular matrix-in primary teeth tissue, during physiological ro
Braz. oral res.. Publicado em: 2013-09
-
2. Reação estromal e proteoglicanos de baixo peso molecular ricos em leucina / Stromal reaction and low molecular weight proteoglycans leucine-rich
During cancer cell growth many tumors exhibit various grades of desmoplasia, unorganized production of fibrous or connective tissue, composed mainly of collagen fibers and myofibroblasts. The accumulation of extracellular matrix (ECM) surrounding tumors directly affects cancer cell proliferation, migration and spread, therefore the study of desmoplasia is of
Publicado em: 2010
-
3. Expression of small leucine-rich proteoglycans: decorin and biglycan, in human normal term placenta and with invasiveness-changed trophoblast pathologies. / Expressão de pequenos proteoglicanos ricos em leucina: decorim e biglicam, em placentas humanas a termo normais e com alterações da invasividade trofoblástica.
O decorim e o biglicam são membros da família dos pequenos proteoglicanos ricos em leucina e possuem importantes funções no controle da proliferação, migração e invasão do citotrofoblasto extraviloso (TEV). O objetivo deste trabalho foi de caracterizar a expressão diferencial e a imunolocalização de decorim e biglicam em placentas humanas normais
Publicado em: 2009
-
4. Expression of proteoglycans biglycan and decorin in the extracellular matrix of deciduous teeth at the resorption process / "Expressões dos proteoglicanos biglican e decorin na matriz extracelular em dentes decíduos humanos durante o processo de rizólise"
As proteínas são importantes componentes da matriz extracelular da polpa dentária e possuem diferentes funções nos tecidos. A literatura odontológica não relata como os proteoglicanos se distribuem e agem na matriz extracelular de dentes decíduos durante o processo fisiológico de rizólise. Foi objetivo do trabalho analisar as expressões dos proteo
Publicado em: 2006
-
5. Cartilagem articular de avestruz : um estudo estrutural e bioquimico
The articular cartilage is a hyaline connective tissue that contains cells and a great amount of extracellular matrix, which is composed of collagen, non-collagenous glycoproteins, and proteoglycans. This work aimed to describe the composition and organization of the extracellular matrix from articular cartilage of ostrich, which is a big bird with commercia
Publicado em: 2004
-
6. Distribution of biglycan and decorin in rat dental tissue
Biglycan and decorin are small leucine-rich proteoglycans that play several biological and structural roles in different tissues and organs. Several reports have indicated that biglycan participates in odontoblast and ameloblast differentiation and in the calcification process. In the present study we show that the expression of biglycan changes from within
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-08
-
7. Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors*
The role of endogenous inducers of inflammation is poorly understood. To produce the proinflammatory master cytokine interleukin (IL)-1β, macrophages need double stimulation with ligands to both Toll-like receptors (TLRs) for IL-1β gene transcription and nucleotide-binding oligomerization domain-like receptors for activation of the inflammasome. It is part
American Society for Biochemistry and Molecular Biology.
-
8. Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats.
The development of bleomycin-induced pulmonary fibrosis in rats was studied over a period of 21 d after an intratracheal instillation of bleomycin. The expression of three small proteoglycans (biglycan, decorin, and fibromodulin), collagen III and TGF-beta 1 was studied by RNA-transfer blot analysis. The proteoglycans were also studied by SDS-polyacrylamide
-
9. ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan
American Diabetes Association.
-
10. Localisation of extracellular matrix components in the embryonic human notochord and axial mesenchyme.
The unsegmented axial mesenchyme is the first anlage of the embryonic vertebral column in amniotes. Its development and differentiation are influenced by the notochord. The appearance of extracellular matrix (ECM) components which may regulate the developmental processes in the human embryonic axial mesenchyme and the notochord was studied in 5 human embryos
-
11. Elevated expression of transforming growth factor-beta and proteoglycan production in experimental glomerulonephritis. Possible role in expansion of the mesangial extracellular matrix.
Glomerular accumulation of extracellular matrix is a prominent feature of progressive glomerulonephritis. Previously, we have shown that transforming growth factor-beta (TGF-beta) is unique among growth factors in regulating the production of the proteoglycans biglycan and decorin by glomerular mesangial cells in vitro. We now provide evidence of an elevated
-
12. The development of articular cartilage: II. The spatial and temporal patterns of glycosaminoglycans and small leucine-rich proteoglycans.
Articular cartilage is both morphologically and biochemically heterogeneous. Its susceptibility to degenerative diseases such as arthritis and its limited repair capacity has made cartilage the focus of intense study; surprisingly, little is known of its development. Using a panel of specific antibodies, we have documented the temporal and spatial patterns o