Auto Antibodies
Mostrando 1-12 de 113 artigos, teses e dissertações.
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1. More than kin, less than kind: one family and the many faces of diabetes in youth
SUMMARY Identification of the correct etiology of diabetes brings important implications for clinical management. In this report, we describe a case of a 4-year old asymptomatic girl with diabetes since age 2, along with several individuals in her family with different etiologies for hyperglycemia identified in youth. Genetic analyses were made by Sanger seq
Arch. Endocrinol. Metab.. Publicado em: 2017-12
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2. In vivo assessment of antiretroviral therapy-associated side effects
Antiretroviral therapy has been associated with side effects, either from the drug itself or in conjunction with the effects of human immunodeficiency virus infection. Here, we evaluated the side effects of the protease inhibitor (PI) indinavir in hamsters consuming a normal or high-fat diet. Indinavir treatment increased the hamster death rate and resulted
Mem. Inst. Oswaldo Cruz. Publicado em: 23/06/2014
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3. Avaliação da imunorreatividade contra desmogleína 1 e Trypanosoma cruzi em população de área endêmica para pênfigo foliáceo / Evaluation of immunoreactivity against desmoglein 1 and Trypanosoma cruzi in population from endemic area for pemphigus foliaceus
Introdução: O pênfigo foliáceo endêmico (PFE) ou Fogo Selvagem (FS) é uma dermatose bolhosa autoimune com auto-anticorpos IgG patogênicos, principalmente da subclasse IgG4, direcionados contra epítopos da desmogleína 1 (Dsg1), uma glicoproteína desmossômica que desempenha papel na adesão celular da epiderme. Os auto-anticorpos ligam-se a domínio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 06/09/2012
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4. Dyslipidemia in patients with juvenile dermatomyositis / Dislipidemia em pacientes com dermatomiosite juvenil
OBJECTIVE: To evaluate the presence of dyslipidemia in JDM and its possible risk factors. METHODS: 25 JDM patients were compared to 25 healthy controls according to demographic data, body composition, fasting lipoproteins, glycemia, insulin, antibodies and muscle enzymes. The following JDM scores were assessed: Disease Activity Score (DAS), Childhood Myositi
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 04/09/2012
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5. Desenvolvimento de imunossensores piezelétrico e eletroquímico para detecção de amostras de interesse agronômico e de saúde / Desenvolvimento de imunossensores piezelétrico e eletroquímico para detecção de amostras de interesse agronômico e de saúde / Development of piezoelectric and electrochemical immunosensors to detect samples of agronomic interest and public health / Development of piezoelectric and electrochemical immunosensors to detect samples of agronomic interest and public health
This work shows development of immunosensors for agronomic interest and public heath. The first was a piezoeletric immunosensor to detect a cysteine peptidase, a potencial biomarker for Xanthomonas citri subsp. citri that cause a citrus Canker. Another was electrochemical immunosensor based on gold nanoparticles as a label and magnetic beads as capture phase
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/07/2012
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6. Correlação clínico-laboratorial e de imagem do lúpus eritematoso sistêmico e da esclerose múltipla no HC/FM/UFG em Goiânia/Goiás de 2009 a 2010: ênfase nas manifestações neurológicas / Correlation of clinical-laboratorial and image of lupus erythematosus and multiple sclerosis in HC/FM/UFG at Goiânia/Goiás, 2009 to 2010: emphasis on neurological manifestations
Lúpus Eritematoso Sistêmico - LES é a doença auto-imune que envolve vários sistemas. No Sistema Nervoso Central - SNC é uma de suas manifestações mais graves. Um dos quadros neurológicos do Lúpus Neuropsiquiátrico - LES-NP, é a Síndrome Desmielinizante - SD. Em raros casos, SD pode ser a primeira manifestação do LES, se assemelhando a Escleros
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/09/2011
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7. Isolamento e identificação de mimetopos de auto-antígenos para utilização em imunodiagnóstico da artrite idiopática juvenil
CHAPTER 2: Juvenile Idiopathic Arthritis (JIA) is a set of chronic diseases characterized by persistent inflammation of joints. "Idiopathic" means that no one knows the cause of illness and "Juvenile" in this case means that the onset of symptoms occurs before 16 years of age. The diagnosis of JIA is clinical and is based on the finding of arthritis in one o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/06/2011
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8. Modificações oxidativas de lipoproteínas de baixa densidade e seus anticorpos : associação com componentes do transporte reverso de colesterol e com a aterosclerose carotídea em adultos sem doença aterosclerótica estabelecida / Oxidative modification of plasma low density lipoproteins and their antibodies : association with the reverse cholesterol transport and carotid atherosclerosis in adults without established aterosclerotic disease
Cardiovascular disease (DCV) is the most common cause of death on western societies, affecting both sexes, with atherosclerosis being the most important underlying pathology. Atherosclerosis is accepted worldwide as an immuneinflammatory disease, in which the participation of the immune system is crucial for the beginning of endothelial dysfunction, fatty st
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/05/2011
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9. Monoclonal auto-antibodies and sera of autoimmune patients react with Plasmodium falciparum and inhibit its in vitro growth
The relationship between autoimmunity and malaria is not well understood. To determine whether autoimmune responses have a protective role during malaria, we studied the pattern of reactivity to plasmodial antigens of sera from 93 patients with 14 different autoimmune diseases (AID) who were not previously exposed to malaria. Sera from patients with 13 diffe
Memórias do Instituto Oswaldo Cruz. Publicado em: 2011-08
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10. Avaliação do modelo de hamster para detecção das alterações lipídicas e cardiotoxicidade associadas à terapia contra o vírus da imunodeficiência humana / Evaluation of the hamster model for the detection of lipidic and cardiotoxicity alterations associated to therapy against human immunodeficiency virus
With the introduction of a new antiretroviral class use, integrants of highly active anti-retroviral therapy (HAART) for the treatment of infections by human immunodeficiency virus, several side effects started to be described.To establish an animal model for the study of these side effects, was chosen specie that have similarities in the lipidic profile and
Publicado em: 2010
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11. Glutamic acid decarboxylase antibodies are indicators of the course, but not of the on-set, of diabetes in middle-aged adults: the atherosclerosis risk in communities study
To efficiently examine the association of glutamic acid decarboxylase antibody (GADA) positivity with the onset and progression of diabetes in middle-aged adults, we performed a case-cohort study representing the ~9-year experience of 10,275 Atherosclerosis Risk in Communities Study participants, initially aged 45-64 years. Antibodies to glutamic acid decarb
Publicado em: 2010
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12. Avaliação da população de linfócitos CD4+ com potencial regulador em pacientes com Imunodeficiência Comum Variável e Deficiência Seletiva de Imunoglobulina A. / Evaluation of the population of CD4+ lymphocytes in patients with Common Variable Immunodeficiency and Selective Immunoglobulin A Deficiency.
Common Variable Immunodeficiency (CVID) and Selective Immunoglobulin A deficiency (IgAD) are the humoral primary immunodeficiencies with the highest incidence in the population. Both diseases are characterized by the absence or significant reduction of serum immunoglobulins. Although several immunological abnormalities have been associated with these disease
Publicado em: 2010