Mechanical properties of the rat cancellous and cortical bone, after a period of immobilization either by plaster cast or tail suspension / Propriedades mecânicas do osso esponjoso e cortical do rato, após período de imobilização por aparelho gessado ou suspensão pela cauda
AUTOR(ES)
Rogério Silva Guagneli
DATA DE PUBLICAÇÃO
2006
RESUMO
The effect of two systems of physical restriction - cast immobilization and tail suspension were studied on the rat long bones and vertebra through mechanical tests. Thirty-six 90 days old female rats were used and divided into three groups: ten were allocated to control and did not receive any treatment. Nine rats had the right posterior limb immobilized in a plaster cast and 12 animals were suspended by the tail. The observation period was three weeks for all the animals. After being killed, the right femur, right tibia and the last lombar vertebra were harvested. Three point mechanical compression tests were performed for the entire tibia whereas for the femur samples from the mid-diaphysis were collected and tested in flexion. The vertebrae were tested in compression at the cancellous bone region. The overall results showed that both methods caused a weakening of the long bones although it was not possible to establish a close comparison between them. For the vertebrae, the cast caused their weakening and, conversely, the tail suspension strengthened the cancellous bone. This result was seen as a biological response to an increased mechanical demand that possibly occur in the lombar region in the suspended position.
ASSUNTO(S)
bone mechanical properties immobilization osso suspensão pela cauda tail suspension propriedades mecânicas imobilização
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