Combined Action of Carbenicillin and Gentamicin on Pseudomonas aeruginosa In Vitro
AUTOR(ES)
Sonne, Minetta
RESUMO
The minimal inhibitory and minimal bactericidal concentrations of carbenicillin and gentamicin were determined for 10 strains of Pseudomonas aeruginosa isolated from the urinary tract. Combinations of the two drugs were tested for possible enhanced activity. Such enhancement was demonstrated in the inhibitory activity of combinations for eight strains. Striking bactericidal activity against five strains was achieved by the combination, whereas neither drug alone in low dosage was capable of bactericidal action. The possible mode of action and the possible merit of pursuing these preliminary findings are discussed.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=377833Documentos Relacionados
- In Vitro Effects of Carbenicillin Combined with Gentamicin or Polymyxin B Against Pseudomonas aeruginosa1
- In Vitro Susceptibility of Pseudomonas aeruginosa to Carbenicillin and the Combination of Carbenicillin and Gentamicin
- Susceptibility of Pseudomonas aeruginosa to Tobramycin or Gentamicin Alone and Combined with Carbenicillin
- Susceptibility of Pseudomonas aeruginosa to Tobramycin or Gentamicin Alone and Combined with Carbenicillin
- Surface action of gentamicin on Pseudomonas aeruginosa.
