Candidose experimental e recuperação de Candida albicans na cavidade bucal de camundongos normais e xerostomicos

AUTOR(ES)
DATA DE PUBLICAÇÃO

1998

RESUMO

The presence of Candida albicans and candidosis development in the oral cavity of normal and sialoadenectomized mice were evaluated after one and four inoculations, with 108 viable cells of C. albicans in the mouth of the animals. The xerostomia was obtained by surgical removal of the major salivary glands from mice (sialoadenectomy) and the recovery of the yeast was accomplished after 1, 2, 3, 5, 8, 15 days and then in intervals of 15 days. The confirmation of the yeast recovered was established through identification of the species and the verification of the killer factor. Candidosis was verified in the epithelium of six are as of the dorsal mice tongue in sagital histological sections stained with hematoxylin &eosin and periodic acid-Schifr. The results obtained showed: a) that xerostomia produced by the sialoadenectomy in the mice propitiated recovery of C. albicans in the oral cavity of the animals in higher number and for more wide periods; b) The quantity of C. Albicans in the oral cavity of sialoadenectomized mice were larger and statistically significant in the recoveries of 30 to 195 days after four inoculations of the yeast; c) candidosis occured in higher number of animals and the lesions were more extensive in the sialoadenectomized mice in relation to the normal

ASSUNTO(S)

candidiase patologia bucal candida albicans camundongo

ACESSO AO ARTIGO

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