Anogenital Cancer
Mostrando 1-12 de 23 artigos, teses e dissertações.
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1. Lack of detection of human papillomavirus DNA in prostate carcinomas in patients from northeastern Brazil
Abstract Prostate cancer is the second most common cancer among men in western populations, and despite its high mortality, its etiology remains unknown. Inflammatory processes are related to the etiology of various types of tumors, and prostate inflammation, in particular, has been associated with prostate cancer carcinogenesis and progression. Human papill
Genet. Mol. Biol.. Publicado em: 2016-03
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2. Glucocorticoid-induced tumor necrosis factor receptor expression in patients with cervical human papillomavirus infection
Introduction The progression of human papillomavirus (HPV) infection in the anogenital tract has been associated with the involvement of cells with regulatory properties. Evidence has shown that glucocorticoid-induced tumor necrosis factor receptor (GITR) is an important surface molecule for the characterization of these cells and proposes that GITR ligand
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-06
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3. HPV vaccination: the beginning of the end of cervical cancer? - A Review
Human papillomavirus (HPV) is responsible for all cases of cervical cancer, as well as a great percentage of other anogenital tumors and oropharyngeal tumors. Since the main etiologic factor for these diseases is a virus, prophylactic measures are the best way to reduce the burden caused by the infection and associated disease. This review brings up to date
Memórias do Instituto Oswaldo Cruz. Publicado em: 2009-02
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4. Estudo in vitro sobre a interação celular e vias endocíticas de papilomavírus humano (HPV) em leucócitos do sangue periférico. / In vitro study on the interaction of human papillomavirus in cell from peripheral blood leukocytes.
Human papillomavirus (HPV) is the primary etiologic agent of anogenital and cervical cancer, caused mainly by the high-risk HPV16 and HPV18 viruses. Recent studies revealed that besides the sexual transmission of HPV, there are other forms of contagion. However, the difficulty in obtaining quantities of viable wild-type or mutant of HPV constitutes a limitin
Publicado em: 2009
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5. Indicações da vacina contra o papilomavirus humano
Estima-se que 20% da população adulta esteja contaminada pelo Papilomavírus humano (HPV) e que anualmente surjam 500 mil novos casos de câncer da cérvix uterina, 70% deles em países em desenvolvimento, além de inúmeros casos de carcinoma anal, quase todos relacionados ao vírus em questão. Esses dados indicam a necessidade de reforçar a prevenção
Revista Brasileira de Coloproctologia. Publicado em: 2008-03
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6. Sexually-transmitted viral diseases in women: clinical and epidemiological aspects and advances in laboratory diagnosis
Sexually transmitted diseases (STDs) have long been known, but they have only recently been recognized as causes of significant long-term morbidity, mainly as a result of increased knowledge concerning viral STDs. The relationship of these diseases with conditions such as anogenital cancer and acquired immunodeficiency syndrome (AIDS) has made viral STDs an
Brazilian Journal of Infectious Diseases. Publicado em: 2005-06
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7. Low frequency of p53 mutations in cervical carcinomas among Brazilian women
Human papillomavirus (HPV) infections of the high-risk types are strongly linked to the development of cervical carcinoma. The HPV oncoproteins E6 and E7 are thought to play a crucial role in this process through their interactions with the p53 protein and the retinoblastoma susceptibility gene product pRb, respectively. E6 binds to p53 protein promoting its
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-06
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8. Human papillomavirus and the development of non-melanoma skin cancer.
Human papillomaviruses (HPV) are increasingly recognised as important human carcinogens. The best established association with human malignancy is that of high-risk mucosal HPV types and anogenital cancer. HPV-induced transformation of anogenital epithelia has been the subject of intense research which has identified the cellular tumour suppressor gene produ
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9. Characterization of human papillomavirus type 66 from an invasive carcinoma of the uterine cervix.
Human papillomavirus (HPV) DNA sequences coexisting with HPV16 and HPV45 were cloned from an invasive cervical carcinoma. The cloned HPV was shown to be a novel type, named HPV66, and is related to HPV56 (an HPV detected in cervical cancer). After screening 160 anogenital biopsies, four specimens exhibited histological features of intraepithelial neoplasia a
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10. The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18.
Human papillomaviruses (HPV-s) have been shown to possess transforming and immortalizing activity for many different, mainly keratinocyte cell lines and they have been detected in 90% of anogenital cancer tissues, which suggests a causative role in the induction of anogenital and other tumours. We have exploited a quantitative assay to identify and character
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11. Epidermal cancer associated with expression of human papillomavirus type 16 E6 and E7 oncogenes in the skin of transgenic mice.
Certain "high-risk" anogenital human papillomaviruses (HPVs) have been associated with the majority of human cervical carcinomas. In these cancers, two papillomaviral genes, E6 and E7, are commonly expressed. In this study we provide evidence that expression of the E6 and E7 genes from the high-risk HPV-16 in the skin of transgenic mice potentiated the devel
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12. Human Papillomavirus (HPV) Type 18 Induces Extended Growth in Primary Human Cervical, Tonsillar, or Foreskin Keratinocytes More Effectively than Other High-Risk Mucosal HPVs▿
Mucosal high-risk (HR) human papillomaviruses (HPVs) that cause cervical and other anogenital cancers also are found in ∼25% of head and neck carcinomas (HNCs), especially those arising in the oropharynx and the tonsils. While many HR HPV types are common in anogenital cancer, over 90% of HPV-positive HNCs harbor HPV type 16 (HPV-16). Using a quantitative
American Society for Microbiology (ASM).