Virus Like Particles
Mostrando 1-12 de 806 artigos, teses e dissertações.
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1. Detection and genetic characterization of Mamastrovirus 5 from Brazilian dogs
Abstract Mamastrovirus 5 (MAstV5), belonging to the Astroviridae (AstV) family, previously known as canine astrovirus or astrovirus-like particles, has been reported in several countries to be associated with viral enteric disease in dogs since the 1980s. Astroviruses have been detected in fecal samples from a wide variety of mammals and birds that are assoc
Braz. J. Microbiol.. Publicado em: 2018-09
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2. RNA viruses in trypanosomatid parasites: a historical overview
Viruses of trypanosomatids are now being extensively studied because of their diversity and the roles they play in flagellates’ biology. Among the most prominent examples are leishmaniaviruses implicated in pathogenesis of Leishmania parasites. Here, we present a historical overview of this field, starting with early reports of virus-like particles on elec
Mem. Inst. Oswaldo Cruz. Publicado em: 19/02/2018
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3. Enveloped and non-enveloped viral-like particles in Trypanosoma cruzi epimastigotes
ABSTRACT Electron microscopy is routinely used to identify viral infections in protozoan parasites. These viruses have been described as non-enveloped and icosahedral structures with a diameter of 30-60 nm. Most of them are classified within the non-segmented dsRNA Totiviridae family. We observed virus-like particles (VLPs) through transmission electron micr
Rev. Inst. Med. trop. S. Paulo. Publicado em: 07/08/2017
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4. Internal control for real-time polymerase chain reaction based on MS2 bacteriophage for RNA viruses diagnostics
BACKGROUND Real-time reverse transcription polymerase chain reaction (RT-PCR) is routinely used to detect viral infections. In Brazil, it is mandatory the use of nucleic acid tests to detect hepatitis C virus (HCV), hepatitis B virus and human immunodeficiency virus in blood banks because of the immunological window. The use of an internal control (IC) is
Mem. Inst. Oswaldo Cruz. Publicado em: 06/04/2017
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5. Ultrastructure of Zika virus particles in cell cultures
Zika virus (ZIKV) has infected thousands of Brazilian people and spread to other American countries since 2015. The introduction of ZIKV brought a strong impact to public health in Brazil. It is of utmost importance to identify a susceptible cell line that will enable the isolation and identification of the virus from patient samples, viral mass production,
Mem. Inst. Oswaldo Cruz. Publicado em: 11/07/2016
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6. Sarcoidosis and chronic hepatitis C: treatment with prednisone and colchicine
Abstract Sarcoidosis is a disease which still has uncertain etiology. Possible environmental causes are cited in the literature, like organic and inorganic particles and infectious agents. Recent studies have demonstrated the occurrence of sarcoidosis in patients with chronic C hepatitis; however, this association remains without statistical or causal eviden
An. Bras. Dermatol.. Publicado em: 2016-04
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7. Production of Brazilian human norovirus VLPs and comparison of purification methods
Abstract Noroviruses (NVs) are responsible for most cases of human nonbacterial gastroenteritis worldwide. Some parameters for the purification of NV virus-like particles (VLPs) such as ease of production and yield were studied for future development of vaccines and diagnostic tools. In this study, VLPs were produced by the expression of the VP1 and VP2 gene
Braz. J. Microbiol.. Publicado em: 09/10/2015
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8. Interleukin-12 gene adjuvant increases the immunogenicity of virus-like particles of human papillomavirus type 16 regional variant strain
Objectives: To analyze the immunogenicity of virus-like particles (VLP) of human papillomavirus type 16 (HPV16) isolated in East China and the adjuvant potential of interleukin-12 (IL-12). Methods: The variant HPV16 L1VLP expressed in sf9 insect cells were purified with cesium chloride gradient centrifugation. BALB/c mice were vaccinated with VLP (L1N), V
Braz J Infect Dis. Publicado em: 2014-01
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9. Production of L1 protein from different types of HPV in Pichia pastoris using an integrative vector
Human papillomavirus (HPV) infection is the most common sexually transmitted disease in the world and is related to the etiology of cervical cancer. The most common high-risk HPV types are 16 and 18; however, the second most prevalent type in the Midwestern region of Brazil is HPV-33. New vaccine strategies against HPV have shown that virus-like particles (V
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-12
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10. Pathological and ultrastructural analysis of surgical lung biopsies in patients with swine-origin influenza type A/H1N1 and acute respiratory failure
BACKGROUND: Cases of H1N1 and other pulmonary infections evolve to acute respiratory failure and death when co-infections or lung injury predominate over the immune response, thus requiring early diagnosis to improve treatment. OBJECTIVE: To perform a detailed histopathological analysis of the open lung biopsy specimens from five patients with ARDS with conf
Clinics. Publicado em: 2010
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11. Development of a therapeutic vaccine against HPV16 / Desenvolvimento de vacina terapêutica contra HPV16
Cervical cancer is the second most common cancer among women worldwide. Most cases (83%) occur in developing countries, where they are found in relatively advanced stages and, consequently, the median survival is about 49% after five years. Therefore, an effective vaccine against HPV infections can lead to control of cancer of the cervix. Although preventabl
Publicado em: 2010
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12. Construção de cDNA infeccioso de Citrus Sudden death-associated virus
The orange is an important fruit, widely spread around the world and very well suited to the climate in Brazil. However, citriculture has suffered a lot with a new disease, called Morte Súbita dos Citros (MSC) (Citros Sudden Death Disease) that has been recognized the first time in 2001 in Minas Gerais State, Brazil. The disease cause severe damages to plan
Publicado em: 2009