Utp
Mostrando 1-12 de 718 artigos, teses e dissertações.
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1. AIM2 inflammasome activation may mediate high mobility group box 1 release in murine allergic rhinitis
Resumo Introdução: A proteína do grupo Box-1 de alta mobilidade participa da patogênese da rinite alérgica. A ativação do inflamassoma pode mediar a liberação de proteína do grupo Box-1 de alta mobilidade. O papel do inflamassoma ausente no melanoma 2 na rinite alérgica permanece incerto. Objetivo: Investigar a função do inflamassoma ausente n
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Does Anzer Propolis Have a Protective Effect on Rabbit Spinal Cord Ischemia/Reperfusion Injury?*
Abstract Introduction: In this study, Anzer propolis, which can only be obtained from the Eastern Black Sea region in Turkey, is studied for its effect on spinal cord ischemia/reperfusion injury. Methods: A total of 12 healthy male New Zealand White rabbits with an average weight of 3.0 to 3.5 kg were separated into two blind and randomized groups: the isc
Brazilian Journal of Cardiovascular Surgery. Publicado em: 2022
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3. A ativação autofágica atenua a neurotoxicidade dos anestésicos locais ao diminuir a atividade da caspase‐3 em ratos
Resumo Introdução e objetivos Os mecanismos de neurotoxicidade dos anestésicos locais são complexos. A apoptose e a autofagia são mecanismos altamente organizados que mantêm a homeostase celular durante o estresse. Estudos revelam que a ativação da autofagia atua como mecanismo de proteção in vitro. Não está claro se a autofagia também desempen
Rev. Bras. Anestesiol.. Publicado em: 2020-12
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4. Comparison of the Apoptotic Effects of Topically Applied Papaverine, Diltiazem, and Nitroprusside to Internal Thoracic Artery
Abstract Objective: To detect and to compare the apoptotic effects of intraoperatively topically applied diltiazem, papaverine, and nitroprusside. Methods: Internal thoracic artery segments of ten patients were obtained during coronary bypass grafting surgery. Each internal thoracic artery segment was divided into four pieces and immersed into four diffe
Braz. J. Cardiovasc. Surg.. Publicado em: 2020-10
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5. Hypertonic saline and pentoxifylline enhance survival, reducing apoptosis and oxidative stress in a rat model of strangulated closed loop small bowel obstruction
OBJECTIVES: Intestinal obstruction has a high mortality rate when therapeutic treatment is delayed. Resuscitation in intestinal obstruction requires a large volume of fluid, and fluid combinations have been studied. Therefore, we evaluated the effects of hypertonic saline solution (HS) with pentoxifylline (PTX) on apoptosis, oxidative stress and survival ra
Clinics. Publicado em: 06/06/2019
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6. DNA damage and primordial follicle activation after in vitro culture of sheep ovarian cortex in Morus nigra leaf extract
RESUMO: Este estudo avaliou o efeito do extrato das folhas de Morus nigra, com ou sem suplementos, sobre a morfologia, a ativação e o dano ao DNA de folículos pré-antrais cultivados inclusos em tecido ovariano. Os ovários foram coletados e divididos em fragmentos, sendo um fixado para análise histológica e ensaio de marcação de terminações dUTP me
Pesq. Vet. Bras.. Publicado em: 2019-01
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7. Protocol for chromosome-specific probe construction using PRINS, micromanipulation and DOP-PCR techniques
ABSTRACT Chromosome-specific probes have been widely used in molecular cytogenetics, being obtained with different methods. In this study, a reproducible protocol for construction of chromosome-specific probes is proposed which associates in situ amplification (PRINS), micromanipulation and degenerate oligonucleotide-primed PCR (DOP-PCR). Human lymphocyte cu
An. Acad. Bras. Ciênc.. Publicado em: 07/12/2017
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8. DESCARTE DE MEDICAMENTOS: UMA REFLEXÃO SOBRE OS POSSÍVEIS RISCOS SANITÁRIOS E AMBIENTAIS
Resumo O presente artigo analisou a forma de descarte de medicamentos pela população do Distrito Federal (DF), refletindo sobre seus possíveis riscos sanitários e ambientais. Para tanto, se realizou um estudo exploratório de corte transversal baseado em entrevistas com moradores das sete Unidades de Planejamento Territorial (UTP) do DF. Dentre os 393 en
Ambient. soc.. Publicado em: 2017-12
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9. Pareamento cromossômico intra e intergenômico em híbridos de capim-elefante e milheto poliploidizados artificialmente
Resumo: O objetivo deste trabalho foi avaliar, por meio da hibridização in situ genômica (GISH), as configurações de pareamento como indicadoras potenciais da recombinação entre cromossomos de diferentes genomas parentais, presentes em dois híbridos interespecíficos (capim-elefante x milheto) poliploidizados artificialmente. Anteras de botões flora
Pesq. agropec. bras.. Publicado em: 2017-09
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10. Impact of propofol on renal ischemia/reperfusion endoplasmic reticulum stress
Abstract Purpose: To investigate the protective mechanisms of propofol (Pro) on renal ischemia/reperfusion (I/R) injury by studying its impact on renal I/R endoplasmic reticulum stress. Methods: Eighteen male Sprague-Dawley rats (SD rats) were randomly divided into three groups: the I/R group, the Pro pretreatment group, and the control group, and corresp
Acta Cir. Bras.. Publicado em: 2017-07
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11. The anesthetic agent sevoflurane attenuates pulmonary acute lung injury by modulating apoptotic pathways
The objective of this study was to evaluate lung protection by the volatile anesthetic sevoflurane (SEVO), which inhibits apoptosis. Male Sprague-Dawley rats (250–280 g; n=18) were randomly divided into three groups. The LPS group received 5 mg/kg endotoxin (lipopolysaccharide), which induced acute lung injury (ALI). The control (CTRL) group received norma
Braz J Med Biol Res. Publicado em: 20/02/2017
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12. Glutamine treatment attenuates hyperglycemia-induced mitochondrial stress and apoptosis in umbilical vein endothelial cells
OBJECTIVE:The aim of this study was to determine the in vitro effect of glutamine and insulin on apoptosis, mitochondrial membrane potential, cell permeability, and inflammatory cytokines in hyperglycemic umbilical vein endothelial cells.MATERIALS AND METHODS:Human umbilical vein endothelial cells were grown and subjected to glutamine and insulin to examine
Clinics. Publicado em: 2015-08