Treatment Of Hepatitis C
Mostrando 1-12 de 418 artigos, teses e dissertações.
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1. Qual a conduta após teste rápido positivo para hepatite C?
Deve-se solicitar o exame de carga viral do HCV (HCV-RNA, realizado por técnica de PCR (polymerase chain reaction) para confirmar a infecção pelo vírus da hepatite C.
O teste rápido dosa o próprio anti-HCV com excelente acurácia, não sendo necessária sua repetição por outro método. Pacientes com anti-HCV reagente por método tradicional
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. Treatment of Hepatitis C with Direct-Acting Antivirals does not Induce Significant Arrhythmias
Abstract Background Chronic Hepatitis C (CHC) therapy with direct-acting antivirals (DAAs) has high efficacy and safety, but some cases of bradyarrhythmias have been described. Objective To evaluate heart rhythm disorders during DAA treatments. Methods Forty-eight patients with CHC (mean 61 years of age; 56% males; 73% HCV genotype 1) were evaluated be
International Journal of Cardiovascular Sciences. Publicado em: 2022
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3. Hepatitis C virus genotypes and associated risk factors in the state of Pará, Northern Brazil
Abstract Background Despite the emergence of more effective therapies, hepatitis C virus (HCV) infection remains a serious public health problem at the global level. Currently, this virus is classified into seven genotypes and 67 subgenotypes, which in turn are distributed heterogeneously in Brazil and worldwide. Studies have shown that this genetic diverge
Braz J Infect Dis. Publicado em: 2020-08
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4. Tenofovir Disoproxil Fumarate: New Chemical Developments and Encouraging in vitro Biological Results for SARS-CoV-2
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led society to live with a serious public health problem. In this sense, repositioning of antiretrovirals has captured the attention of the scientific community. Tenofovir disoproxil fumarate (TDF) is an antiretroviral compound that is used to treat acquired immune defic
J. Braz. Chem. Soc.. Publicado em: 2020-08
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5. Incidence of depression in patients with hepatitis C treated with direct-acting antivirals
Objective: Depression has been associated with hepatitis C, as well as with its treatment with proinflammatory cytokines (i.e., interferon). The new direct-acting antiviral agents (DAAs) have minimal adverse effects and high potency, with a direct inhibitory effect on non-structural viral proteins. We studied the incidence and associated factors of depressi
Braz. J. Psychiatry. Publicado em: 2020-02
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6. Treatment of chronic hepatitis C in patients with chronic kidney disease with Sofosbuvir-basead regimes
ABSTRACT Background: To analyze the effectiveness and the safety of Sofosbuvir-based regimens to treat patients with chronic hepatitis C virus (HCV) infection and chronic kidney disease (CKD). Methods: A retrospective, observational study in patients with chronic HCV infection and CKD treated with Sofosbuvir-based regimens was performed. Liver fibrosis, co
Braz J Infect Dis. Publicado em: 2020-02
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7. Prevalence of coinfections in women living with human immunodeficiency virus in Northeast Brazil
Abstract INTRODUCTION: Despite the success of antiretrovirals, human immunodeficiency virus (HIV) coinfections continue to cause mortality. We investigated the prevalence of coinfections in women with HIV/acquired immunodeficiency syndrome in Sergipe, Brazil. METHODS: We conducted a cross-sectional study. The coinfections investigated were syphilis, hepa
Rev. Soc. Bras. Med. Trop.. Publicado em: 20/12/2019
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8. Chemical constituents from the fruits of Schisandra sphenanthera and their cytotoxicity activity
Abstract Schisandra sphenanthera Rehder & E.H. Wilson, Schisandraceae, is well known as a type of traditional medicine for the treatment of hepatitis, diarrhea and insomnia in Asia. It was also reported to have antiviral and anti-HIV activities. Using various chromatographic resins and isolation techniques, a new lignan (1), erythro-4-(3,4-dimethoxyphenyl)-4
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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9. Protective effect of kinsenoside on acute alcohol-induced liver injury in mice
Abstract Anoectochilus roxburghii (Wall.) Lindl., Orchidaceae, is a Chinese medicinal plant which can be effective for some diseases such as hepatitis, nephritis, pneumonia. Its active ingredient is kinsenoside. The mechanisms of kinsenoside on the liver-protective effect have not been fully explored until today. The present study was aimed to investigate th
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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10. SUSTAINED VIROLOGIC RESPONSE RATE IN CHRONIC HEPATITIS C PATIENTS THROUGH DIRECT-ACTING ANTIVIRALS THERAPY
RESUMO CONTEXTO: O manejo e a possibilidade de erradicação da infecção pelo vírus da hepatite C têm sido muito pesquisados nos últimos anos pela importância que representam na saúde pública para a população mundial. A obtenção de dados que auxiliem o enfrentamento dessa patologia resulta na melhor qualidade de vida dos seus portadores. O pres
Arq. Gastroenterol.. Publicado em: 28/11/2019
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11. Characteristics of a hepatitis C patient cohort at a specialized tertiary care facility: Identifying criteria to improve the allocation of public health resources
OBJECTIVES: Our objective was to analyze, in a population treated for hepatitis C infection at a tertiary care treatment unit, the prevalence of comorbidities and extrahepatic manifestations, the range and degree of the clinical complexity and the associations between advanced liver disease and clinical variables. METHODS: Medical records from chronically
Clinics. Publicado em: 28/10/2019
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12. [PROVISIONAL] Resistance mutations of NS3 and NS5b in treatment-naïve patients infected with Hepatitis C virus in Santa Catarina and Rio Grande do Sul States, Brazil
Abstract Hepatitis C virus (HCV) infection is a worldwide health problem. Nowadays, direct-acting antiviral agents (DAAs) are the main treatment; however, the high level of variability of HCV lead to development of resistance-associated variants (RAVs). Thus, look into the RAVs among infected patients is an important tool for monitoring the efficacy of the t
Genet. Mol. Biol.. Publicado em: 21/10/2019