Transforming Growth Factor Beta
Mostrando 25-36 de 685 artigos, teses e dissertações.
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25. Involvement of transforming growth factor beta-1 (TGFβ1) cytokine and FOXP3 transcription factor genetic polymorphisms in hematological malignancies
Hematological malignancies (HM) are a group of neoplastic diseases that arise from hematologic cell lineages. Transforming growth factor beta 1 (TGFβ1) is shown to negatively regulate normal and malignant hematopoiesis and, in immunological context, to promote T cell exhaustion and generation of regulatory T cells, which are shown to be deleterious in cance
Braz. arch. biol. technol.. Publicado em: 01/05/2015
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26. Spontaneous hepatitis C viral clearance and hepatitis C chronic infection are associated with distinct cytokine profiles in Mexican patients
The mechanisms related to the spontaneous clearance of hepatitis C virus (HCV) have been primarily studied in regions where the infection is endemic. Results of prior studies have been extrapolated to populations with low endemicity, such as Mexico. Herein, we determined the cytokine profiles in serum samples from Mexican patients who spontaneously cleared H
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-04
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27. Increased angiogenesis in primary myelofibrosis: latent transforming growth factor-β as a possible angiogenic factor
Objective: The aim of this work was to demonstrate a possible relationship between anti-latency-associated peptide human latent transforming growth factor beta 1 (latent TGF-β1) expression in megakaryocytes and microvascular density in bone marrow biopsies from patients with essential thrombocythemia and primary myelofibrosis. Methods: Microvascular dens
Rev. Bras. Hematol. Hemoter.. Publicado em: 2014-10
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28. Effect of physical training on liver expression of activin A and follistatin in a nonalcoholic fatty liver disease model in rats
Nonalcoholic fatty liver disease (NAFLD) is characterized by fat accumulation in the liver and is associated with obesity and insulin resistance. Activin A is a member of the transforming growth factor beta (TGF)-β superfamily and inhibits hepatocyte growth. Follistatin antagonizes the biological actions of activin. Exercise is an important therapeutic stra
Braz J Med Biol Res. Publicado em: 25/07/2014
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29. Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A
Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism. In the acute hepatitis model, quercetin (2.5 mg/kg) was injected iv into mice 30 min after concanavalin A (Con A) challenge. Mice were sacrificed 4
Braz J Med Biol Res. Publicado em: 24/06/2014
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30. Host genetic factors in American cutaneous leishmaniasis: a critical appraisal of studies conducted in an endemic area of Brazil
American cutaneous leishmaniasis (ACL) is a vector-transmitted infectious disease with an estimated 1.5 million new cases per year. In Brazil, ACL represents a significant public health problem, with approximately 30,000 new reported cases annually, representing an incidence of 18.5 cases per 100,000 inhabitants. Corte de Pedra is in a region endemic for ACL
Mem. Inst. Oswaldo Cruz. Publicado em: 27/05/2014
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31. TGF-β1 on induced osteogenic differentiation of human dermal fibroblast
PURPOSE: To evaluate the role of transforming growth factor beta 1 (TGF-β1) on the induced osteogenic differentiation of human dermal fibroblasts. METHODS: We performed four groups with cultured dermal fibroblasts according to the culture medium: CONTROL (DMEM culture medium); TGF-β1 (DMEM culture medium with 10 ng/ml of TGF-β1); OSTEOG (DMEM culture med
Acta Cir. Bras.. Publicado em: 2014
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32. Bone remodeling at microscrew interface near extraction site in the beagle dog mandible-histologic and immunohistochemical analyses
Extraction is often used as part of orthodontic therapy, and good control of anchorage is a key step after extraction. Although microscrews can be implanted close to the extraction site in order to achieve orthodontic support, the efficiency of bone remodeling at the implant-bone interface near the extraction region is dubious. OBJECTIVE: The purpose of th
J. Appl. Oral Sci.. Publicado em: 2013-09
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33. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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34. Expressão de fator de crescimento transformador Beta e inibidores teciduais de metaloproteinases 1 e 2 em próstatas caninas normais e com lesões proliferativas / Expression of tansforming growth factor B and tissue inhibitor of metalloproteianse 1 and 2 in normal canine prostates and with proliferative lessions
The canine gland has drawn interest for research due to its similarities with the human prostate and the great incidence of lesions. Moreover, the canine prostate shows high incidence of diseases. The main lesions that affect the prostate are prostatitis, benign prostatic hyperplasia (BPH), cysts and adenocarcinoma. Recently attention has been given to lesio
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 08/03/2012
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35. Fibrose cardíaca em camundongos mdx idosos : efeito da suramina, um bloqueador do TGF-ß1 / Cardiac fibrosis in older mdx mice : effects of sumarim, a blocker of TGF-ß1
A Distrofia muscular de Duchenne (DMD) é uma doença caracterizada pela fraqueza muscular progressiva que leva à insuficiência respiratória e cardíaca, resultando em morte por volta dos 30 anos de idade. No camundongo mdx, modelo experimental da DMD, os músculos diafragma e cardíaco são severamente afetados apresentando fibrose semelhante à observad
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/02/2012
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36. Beneficial effect of ubiquinol, the reduced form of coenzyme Q10, on cyclosporine nephrotoxicity
BACKGROUND: Cyclosporine (CyA) nephrotoxicity is partly due to some oxidative stress. Ubiquinol, the reduced form of coenzyme Q10 (rCoQ10), has recently gained attention for its anti-oxidative potential. The aim of this study is to evaluate the effect of rCoQ10 on a CyA nephrotoxic rat model. MATERIALS AND METHODS: Six-week-old male Wistar rats were divided
International braz j urol. Publicado em: 2012-04