Toxoide Tetanico Tt
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1. Toll-like receptor 4 (TLR4) na modulação da imunidade do tipo 2. / Toll-like receptor 4 (TLR4) and modulation of Th2 immunity.
Epidemiological and experimental data suggest that bacterial lipopolysaccharides (LPS) can either protect from or exacerbate allergic asthma. LPS triggers immune responses through Toll-like receptor (TLR) 4 that in turn activates two major signaling pathways via either MyD88 or TRIF adaptor proteins. LPS is a pro-Th1 adjuvant while aluminum hydroxide (Alum)
Publicado em: 2008