Toxicological Parameters
Mostrando 1-12 de 50 artigos, teses e dissertações.
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1. Toxicological evaluation of Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark extract: Acute and subchronic studies in mice
This study evaluated the safety of Lafoensia pacari A. St.-Hil. (Lythraceae) stem bark hydroalcoholic extract (LPE) through acute and subchronic toxicological assessments in mice. In the acute toxicity evaluation, a single 2000 mg/kg oral dose of LPE was administered to mice and clinical observations were conducted for 14 days. For subchronic toxicity, LPE d
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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2. Chemical characterization and toxicological assessment of hydroethanolic extract of Mandevilla velame xylopodium
Abstract The present study was aimed to characterize the chemical profile and evaluate the cytotoxicity and sub-chronic toxicity of the hydroethanolic extract of the xylopodium Mandevilla velame (A.St.-Hil.) Pichon, Apocynaceae. Chemical profile was analyzed by high performance liquid chromatography. Cytotoxic potential of hydroethanolic extract of the xylop
Rev. bras. farmacogn.. Publicado em: 09/12/2019
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3. Sub-chronic toxicity evaluation of Dryopteris filix-mas (L.) schott, leaf extract in albino rats
This study evaluated the acute and sub-chronic toxicities of ethanol leaf extract of Dryopteris filix-mas. Acute toxicity and phytochemical tests on ethanol leaf extract were determined. In sub-chronic toxicity test, animals were treated with 62.5, 125, 250 and 500 mg/kg of extract every day for 90 days. Blood samples were collected via retro-orbital punctur
Braz. J. Pharm. Sci.. Publicado em: 03/10/2019
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4. Changes in physicochemical and toxicological parameters of waters of Trincheira's River caused by road construction
Resumo Infraestruturas rodoviárias podem afetar áreas naturais com grande intensidade. Um trevo e uma trincheira foram construídas na cidade de Francisco Beltrão-Paraná-Brasil sobre um corpo d'água chamado Rio da Trincheira. O objetivo do presente estudo foi avaliar a qualidade de suas águas, em termos físico-químicos e toxicológicos, em quatro pon
Rev. Ambient. Água. Publicado em: 18/07/2019
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5. CONTRIBUIÇÃO QUÍMICA PARA O PLANO DE GERENCIAMENTO DE ÁGUAS RESIDUAIS DE SERVIÇOS DE SAÚDE
In this study were analyzed the main lines of health care waste at the Hospital of the Federal University of Paraná (HC/UFPR), performing an inventory that aims from awareness, characterization, until a viable wastewater treatment proposal for the institution. In this context, were emphasized physical and chemical analyses parameters, inorganic species foll
Quím. Nova. Publicado em: 2017-06
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6. Glutamine dipeptide supplementation improves clinical responses in patients with diabetic foot syndrome
ABSTRACT The effect of glutamine dipeptide (GDP) supplementation in patients with diabetic foot syndrome was evaluated. A total of 22 patients took part in the study. GDP was supplied in 10 g sachets, and was dissolved in water immediately before use, with ingestion once a day, after lunch or after dinner (20 g/day) over a period of 30 days. Quantification o
Braz. J. Pharm. Sci.. Publicado em: 2016-09
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7. Contamination index. A novel parameter for metal and pesticide analyses in maternal blood and umbilical cord
ABSTRACT PURPOSE: To evaluate the contamination index of metals and pesticides in pregnant women, and to relate this to perinatal outcomes. METHODS: Descriptive, retrospective, exploratory study, developed from existing secondary data analyses at Level III maternity center. A total of 40 mothers with their newborns (NB), living in a rural area in Botucat
Acta Cir. Bras.. Publicado em: 2016-07
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8. Immunomodulatory and toxicological evaluation of the fruit seeds from Platonia insignis, a native species from Brazilian Amazon Rainforest
Abstract The “bacuri” (Platonia insignis Mart., Clusiaceae) is a native tropical fruit from the Brazilian Amazon and Northeast Regions. Its seeds are used to treat inflammatory diseases, diarrhea and skin problems in traditional medical practices. Regarding its widespread medicinal uses, it is important to evaluate the biological and toxicological potent
Rev. bras. farmacogn.. Publicado em: 2016-02
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9. ARSÊNIO E ARROZ: TOXICIDADE, METABOLISMO E SEGURANÇA ALIMENTAR
Arsenic is considered a semimetal, and its wide distribution in the Earth's crust in different chemical forms, including organic and inorganic species, has a great deal of influence on the mechanisms of toxicity. Exposure to arsenic can be either through occupational practice (use of pesticides) or by the consumption of water and food containing the element.
Quím. Nova. Publicado em: 2015-01
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10. Estudo da atividade citotóxica do poliacetileno 5-octa-2, 4, 6-triinil-furan-2(5H)-ona / Study of the cytotoxic activity of polyacetylene 5-octa-2,4,6-triinil-furan-2 (5H)-one
Skin cancers are the most common types of cancer in Brazil, and correspond to around 25% of all malignant tumors recorded. Of these, melanoma represents at least 5% and is characterized by its high metastatic power. The development of anticancer agents from natural products is considered critical to pharmacology, and interest in the development of more effec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/06/2012
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11. Toxicological evaluation of ethanolic extract of Lychnophora trichocarpha, Brazilian arnica
The species of the genus Lychnophora, Asteraceae, are popularly known as "arnica" and are native from Brazilian savana (Cerrado). They are widely used in Brazilian folk medicine as anti-inflammatory, to treat bruise, pain, rheumatism and for insect bites. For evaluation of acute toxicity, the ethanolic extract was given to albino female and male mice. In ope
Rev. bras. farmacogn.. Publicado em: 17/07/2012
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12. Anti-ulcer activity of Synadenium grantii latex
Synadenium grantii Hook f., Euphorbiaceae, is popularly known as leitosinha or janaúba. The diluted latex (18 drops/L of water) is commonly used in the south of Brazil to treat gastric disturbances. This study evaluated phytochemical screening and toxicity using Artemia salina Leach of crude bark extract and also latex. The toxicity and the anti-ulcer activ
Rev. bras. farmacogn.. Publicado em: 17/04/2012