Toxicity Cell Culture
Mostrando 1-12 de 202 artigos, teses e dissertações.
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1. DISINFECTION PROTOCOL AND IN VITRO GERMINATION OF SEEDS OF Dalbergia nigra
ABSTRACT The Atlantic Forest is a biome that has suffered anthropic actions, such as the extraction of hardwood, which can lead to the extinction of endemic species of great economic and ecological value, such as Dalbergia nigra. In this perspective, large-scale multiplication studies are necessary to contribute to the conservation of this species. The objec
CERNE. Publicado em: 2020-06
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2. Increased whitening efficacy and reduced cytotoxicity are achieved by the chemical activation of a highly concentrated hydrogen peroxide bleaching gel
Abstract Objective This study was designed for the chemical activation of a 35% hydrogen peroxide (H2O2) bleaching gel to increase its whitening effectiveness and reduce its toxicity. Methodology First, the bleaching gel - associated or not with ferrous sulfate (FS), manganese chloride (MC), peroxidase (PR), or catalase (CT) - was applied (3x 15 min) to
J. Appl. Oral Sci.. Publicado em: 12/08/2019
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3. In vitro and in vivo cell tracking of PKH26-labeled osteoblasts cultured on PLDLA scaffolds
Abstract The importance of monitoring in vivo interaction that occurs between cells /bio/tissue recipient in the understanding of tissue regeneration processes becomes ever greater. This study aims to monitor and evaluate the influence of scaffold implants of poly (L-co-D, L lactic acid) - PLDLA synthesized in the laboratory, previously cultured with primary
Polímeros. Publicado em: 2017-03
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4. Response of a co-culture model of epithelial cells and gingival fibroblasts to zoledronic acid
Abstract Osteonecrosis of the jaw is an adverse effect of bisphosphonates. While the etiopathogenesis of this condition has been investigated, the interactions and effects of bisphosphonates on oral mucosa cells remain unclear. It is hypothesized that cell culture models, such as co-culture or three-dimensional cell culture models, can provide valuable insig
Braz. oral res.. Publicado em: 28/11/2016
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5. Antifungal activity of extracts from Atacama Desert fungi againstParacoccidioides brasiliensis and identification ofAspergillus felis as a promising source of natural bioactive compounds
Fungi of the genus Paracoccidioides are responsible for paracoccidioidomycosis. The occurrence of drug toxicity and relapse in this disease justify the development of new antifungal agents. Compounds extracted from fungal extract have showing antifungal activity. Extracts of 78 fungi isolated from rocks of the Atacama Desert were tested in a microdilution as
Mem. Inst. Oswaldo Cruz. Publicado em: 2016-03
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6. The Risk Evaluation of Tungsten Oxide Nanoparticles in Cultured Rat Liver Cells for Its Safe Applications in Nanotechnology
Tungsten (VI) oxide (WO3) nanoparticles (NPs) are used for many industrial purposes in everyday life. However, their effects on human health have not been sufficiently evaluated. Therefore, the present study was designed to investigate the toxicity potentials of various concentrations (0 to 1000 ppm) of WO3NPs (<100 nm particle size) in cultured primary rat
Braz. arch. biol. technol.. Publicado em: 2014-08
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7. O efeito pró-apoptótico de oligômeros da amilina humana não é potencializado pela lipotoxicidade em ilhotas pancreáticas de rato em cultura / The pro-apoptotic effect of human amylin oligomers is not potentiated by lipotoxicity in rat pancreatic islets in culture
The amyloid deposit is a common histopathological feature in patients with type 2 diabetes mellitus (T2DM) and it seems to be related to the pancreatic beta cell dysfunction characteristic of this disease. A study previously developed in our laboratory found that human amylin oligomers decrease mRNA expression of the glucose-dependent insulinotropic polypept
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/07/2012
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8. Produção de carotenoides em culturas in vitro de Cleome rosea Vahl ex DC (Capparaceae) e avaliação de sua toxicidade e potencial antioxidante / Carotenoid production in vitro cultures of Cleome rosea Vahl ex DC (Capparaceae) and evaluation of toxicity and antioxidant potential.
The production and optimization of plants secondary metabolites with medicinal value have been achieved by using plant tissue culture techniques, which have showed great relevance when considering the conservation status of a species or their occurrence in degraded environments. The present study assessed the production of carotenoids in callus and cell susp
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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9. In vitro cultivation of canine multipotent mesenchymal stromal cells on collagen membranes treated with hyaluronic acid for cell therapy and tissue regeneration
Support structures for dermal regeneration are composed of biodegradable and bioresorbable polymers, animal skin or tendons, or are bacteria products. The use of such materials is controversial due to their low efficiency. An important area within tissue engineering is the application of multipotent mesenchymal stromal cells (MSCs) to reparative surgery. The
Braz J Med Biol Res. Publicado em: 2012-12
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10. Determination of in vivo toxicity and in vitro cytotoxicity of venom from the Cypriot blunt-nosed viper Macrovipera lebetina lebetina and antivenom production
The venomous Levantine viper, Macrovipera lebetina lebetina is endemic to Cyprus. The objective of this study was to investigate in vitro cytotoxicity, in vivo lethality, and antivenom production followed by a re-immunization schedule in mice against Macrovipera lebetina lebetina venom. The LD50 value was estimated as 7.58 mg/kg within 24 hours by different
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2012
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11. Efeito de uma fosfolipase A2 básica isolada da peçonha de Bothropoides pauloensis (Bothrops pauloensis) sobre formas promastigota de Leishmania (Leishmania) amazonensis
CHAPTER 2: Leishmaniasis is a group of diseases caused by protozoa of Leishmania genus. The currently available treatment for this disease presents high toxicity and cost, parasite resistance, and difficulties of healing. In this sense, the development of new strategies for treatment of leishmaniasis is indispensable and snake venoms appear as an important n
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/07/2011
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12. Desenvolvimento de metodologia para controle das larvas de Limnoperna fortunei com o uso de radiação ultravioleta e seus impactos sobre Microscystis aeruginosa potencialmente presentes na água superficial
L. fortunei (Dunker, 1857), commonly known as golden mussel comes from Southeast Asia. It might have been unintentionally introduced in our water sources through ballast water, with the first records in 1991, in Rio de la Plata, near Buenos Aires, Argentina, South America. In Brazil it was first seen in 1998, in Jacuí Delta, opposite Porto Alegre¿s harbor.
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 2011