Therapeutic Play
Mostrando 1-12 de 303 artigos, teses e dissertações.
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1. The endocannabinoid system in social anxiety disorder: from pathophysiology to novel therapeutics
Social anxiety disorder (SAD) is a highly prevalent psychiatric disorder that presents with an early age of onset, chronic disease course, and increased risk of psychiatric comorbidity. Current treatment options for SAD are associated with low response rates, suboptimal efficacy, and possible risk of adverse effects. Investigation of new neurobiological mech
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. BIOMARCADORES MOLECULARES DE DOENÇAS HUMANAS: CONCEITOS FUNDAMENTAIS, MODELOS DE ESTUDO E APLICAÇÕES CLÍNICAS
Molecular biomarkers correspond to all endogenous or exogenous biomolecules, whose presence or alteration in metabolic pathways indicate the response of a biological system to a disturbance caused by internal or external factors. The search for biomarkers has allowed deepening the knowledge of complex pathophysiological mechanisms of diseases, interactions w
Química Nova. Publicado em: 2022
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3. Association Between Lipid Profile and Clinical Manifestations in Sickle Cell Anemia: A Systematic Review
Abstract Introduction Sickle cell anemia (SCA) is a genetic disease associated with frequent episodes of acute illness. Changes in the lipid profile and a chronic inflammatory process make up the molecular aspects observed in this disease. Associations between these mechanisms and clinical manifestations could thus define severity profiles and therapeutic
International Journal of Cardiovascular Sciences. Publicado em: 2022
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4. Blood microRNA expressions in patients with mild to moderate psoriasis and the relationship between microRNAs and psoriasis activity,
Abstract Background: In recent studies, microRNAs (mi-RNAs) have been shown to play an important role in psoriasis pathogenesis. However, studies evaluating mi-RNAs in the blood of psoriasis patients including a large number of mi-RNA panels are scarce. Objective: The authors aimed to assess mi-RNA expressions in blood samples of psoriasis patients, as wel
An. Bras. Dermatol.. Publicado em: 2020-12
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5. Ensaio sobre o método clínico na psicanálise com crianças
A finalidade deste ensaio é discutir a qualidade do método clínico na psicanálise com crianças, a partir das contribuições de D. W. Winnicott sobre o brincar e o conceito elasticidade da técnica de S. Ferenczi. Uma vinheta ilustra como novas estratégias clínicas de escuta e enquadramento interrogam os valores metodológicos e éticos, problematizan
Rev. latinoam. psicopatol. fundam.. Publicado em: 17/01/2020
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6. lncRNA OIP5-AS1 targets ROCK1 to promote cell proliferation and inhibit cell apoptosis through a mechanism involving miR-143-3p in cervical cancer
Opa-interacting protein 5 antisense transcript 1 (OIP5-AS1) is one kind of cytoplasmic long non-coding RNA (lncRNA), which has been demonstrated to play a critical function in multiple cancers. However, the detailed mechanism of OIP5-AS1 in the regulation of cervical cancer progression is still obscure. Here, we demonstrated that lncRNA OIP5-AS1 was upregula
Braz J Med Biol Res. Publicado em: 2020-01
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7. Insulin resistance is associated with Sfrp5 in obstructive sleep apnea,
Resumo Introdução: A apneia obstrutiva do sono, uma doença comum, é geralmente complicada com resistência à insulina e diabetes melito tipo 2. Acredita-se que a adipocina possa ter um papel importante no desenvolvimento de resistência à insulina e diabetes melito tipo 2 na apneia obstrutiva do sono. Objetivo: Avaliar se a proteína secretada relaci
Braz. j. otorhinolaryngol.. Publicado em: 13/12/2019
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8. Biochemical and Molecular Mechanisms of Glucose Uptake Stimulated by Physical Exercise in Insulin Resistance State: Role of Inflammation
Resumo A obesidade associada à inflamação sistêmica induz resistência à insulina (RI), com consequente hiperglicemia crônica. Este processo envolve o aumento na liberação de citocinas pró-inflamatórias, ativação da enzima c-Jun N-terminal cinase (JNK), do fator nuclear kappa-B (NF-κB) e dos receptores do tipo Toll 4 (TLR4). Dentre as ferramenta
Arq. Bras. Cardiol.. Publicado em: 21/10/2019
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9. HISTORICAL PERSPECTIVE OF GASTROESOPHAGEAL REFLUX DISEASE CLINICAL TREATMENT
RESUMO CONTEXTO: A doença do refluxo gastroesofágico (DRGE) é uma das doenças gastrointestinais mais prevalentes, resultando em limitações significativas na qualidade de vida dos pacientes e, também, relevante utilização de recursos médicos. Um melhor entendimento da fisiopatologia da doença nas últimas cinco décadas tem favorecido a evoluçã
Arq. Gastroenterol.. Publicado em: 26/08/2019
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10. Proteomic analysis of excretory-secretory products from young adults of Angiostrongylus cantonensis
BACKGROUND Angiostrongyliasis is caused by the nematode Angiostrongylus cantonensis and can lead to eosinophilic meningitis and meningoencephalitis in humans. The young adult worms play central pathogenic roles in the central nervous system (CNS); however, the underlying mechanism is unclear. Excretory-secretory products (ESPs) are good investigation targe
Mem. Inst. Oswaldo Cruz. Publicado em: 19/06/2019
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11. Hydrogen sulfide protects H9c2 cardiomyoblasts against H2O2-induced apoptosis
Reactive oxygen species (ROS) are highly reactive chemical species that may cause irreversible tissue damage, and play a critical role in cardiovascular diseases. Hydrogen sulfide (H2S) is a gasotransmitter that acts as a ROS scavenger with cardio-protective effects. In this study, we investigated the cytoprotective effect of H2S against H2O2-induced apoptos
Braz J Med Biol Res. Publicado em: 15/04/2019
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12. TEACHING OF THERAPEUTIC PLAY AT THE UNDERGRADUATE LEVEL IN NURSING: DIDACTIC ACTIONS AND STRATEGIES USED BY PROFESSORS
RESUMO Objetivo: apresentar e discutir ações e estratégias utilizadas por professores que ensinam o brinquedo terapêutico nos Cursos de Graduação em Enfermagem. Método: pesquisa qualitativa, que utilizou o Interacionismo Simbólico como referencial teórico e metodológico a Teoria Fundamentada nos Dados. O cenário constituiu-se de disciplinas que
Texto contexto - enferm.. Publicado em: 14/02/2019