VALIDAÇÃO DE MÉTODO POR MEFS-HS/CG-EM PARA DETERMINAÇÃO DE CARBARIL EM PLASMA SANGUÍNEO

The aim this research is to develop a HS-SPME/GC-MS method to analyze the carbaryl in blood plasma samples of the rural workers, who live round the perimeter of Chapada do Apodi-CE. This was achieved by chromatographic signal of the 1-naftol, degradation product of carbaryl with the intention of evaluating the degree of exposure of the workers to pesticides, causing chromosome abnormalities as already evidence in appropriate literature. Three different types of covered SPME fibers were tested and a full factorial design with central point in two levels. The variables optimized were temperature...