TÉCNICAS AVANÇADAS PARA A DIFERENCIAÇÃO DE ISÔMEROS POR ESPECTROMETRIA DE MASSAS

Mass spectrometry (MS) is a powerful and widespread technique but is inherently uncapable to differentiate species with same m/z ratio. For this reason, many classical approaches were developed based on differential fragmentation patterns in tandem MS. More recently, new techniques for isomer identification in MS were developed, and we highlight the photodissociation techniques that will be discussed in this review. This photodissociation techniques explore the selective activation of isomers to induce isomer specific dissociations in the gas-phase that depend on the spectroscopic features of ...