SENSITIVITY ANALYSIS FOR MODEL COMPARISON AND SELECTION IN TISSUE ENGINEERING

ABSTRACT Computational modeling has been proven to be very useful in tissue engineering over the past years. Because the model is a simplification of the experimental system, the processes accounted for in the model should be analyzed carefully. However, new and complex models are usually proposed without a clear comparison with the basic ones. In this study, the contribution of oxygen to Contois growth kinetics and porosity variation with time due to polymer degradation was evaluated through a sensitivity analysis. The effect of initial glucose concentration, porosity and thickness of the sca...