Mean platelet volume and neutrophil to lymphocyte ratio decrease in patients with depression with antidepressant treatment

Abstract Objective Not only white blood cells but also platelets are being considered in inflammatory reactions from now on. Mean platelet volume (MPV) and neutrophil to lymphocyte ratio (NLR) have been shown to change in inflammatory diseases like myocardial infarction, stroke and implicated in psychiatric disorders nowadays. Our first aim is to investigate the relation of MPV and NLR with depression and secondly to assess if they change with the treatment of depression. Methods Forty-nine patients diagnosed with major depressive disorder (MDD) and hospitalized in a university hospital ps...