25/02/2011

Assessment of hepatoprotective effect of Tecomella undulata (Sm.) Seem., Bignoniaceae, on paracetamol-induced hepatotoxicity in rats

The aim of the present study was to validate the hepatoprotective activity of bark of Tecomella undulata (Sm.) Seem., Biognoniaceae, against paracetamol (PCM) induced hepatic damage. Chloroform soluble fraction (Fraction-I), acetone soluble fraction (Fraction-II), methanol soluble fraction (Fraction-III) and methanol insoluble fraction (Fraction-IV) of ethanolic extract of bark of T. undulata were evaluated for hepatoprotective activity against paracetamol induced hepatic damage using biochemical, morphological, functional and histopathological studies. The methanol soluble fraction (Fraction-...

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