Tetrazol
Mostrando 1-12 de 18 artigos, teses e dissertações.
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1. Modificação química da poliacrilonitrila com grupos tetrazol assistida por micro-ondas / Chemical modification of polyacrylonitrile with tetrazole grpups assisted by microwave
Nos últimos anos, a irradiação por micro-ondas tem sido cada vez mais usada na síntese de varias moléculas orgânicas, devido a uma série de vantagens que essa nova tecnologia apresenta. Até o momento, existem poucos estudos sobre polimerizações assistidas por micro-ondas e menos ainda sobre a modificação de polímeros usando essa nova fonte de en
Publicado em: 2011
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2. Avaliação do copolímero de acrilonitrila e 5-vinil-tetrazol na eficiência de inibição de corrosão química / Evaluation of acrylonitrile and 5 vinil-tetrazole copolymer in the efficiency of chemical corrosion inhibition
A corrosão é um processo resultante da ação do meio sobre um determinado material, causando sua deterioração. Em geral, essa deterioração causa prejuízos incalculáveis, fazendo com que o material se torne inadequado ao uso. Os heterocíclicos apresentam inúmeras aplicações tecnológicas e em alguns casos médico-farmacológicas. Mais recentement
Publicado em: 2010
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3. Evaluation of the cytocompatibility of mixed bovine bone
O tratamento do osso bovino com peróxidos e agentes caotrópicos visa à obtenção de uma matriz óssea acelular, com manutenção do complexo colágeno-apatita e maior resistência mecânica, denominada osso bovino misto (OBM). O objetivo desse estudo foi avaliar a citocompatitiblidade do osso bovino misto e a interação célula-OBM. Células Balb-c 3T3
Brazilian Dental Journal. Publicado em: 2007
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4. Síntese de cristais líquidos derivados dos heterociclos oxazol e tetrazol
Este trabalho relata a síntese, caracterização e o estudo das propriedades mesomórficas de duas novas séries homólogas de compostos derivados de 4-[5-(2-n-alquiltetrazolil)]-fenil-3- carboxi-5-(4-octilfenil)-isoxazol (Série I) e 4-[5-(2-n-alquiltetrazolil)]-fenil-5-benzoiloxi-3- (4-octiloxifenil)-1,2,4-oxadiazol (Série II). A metodologia sintética u
Publicado em: 2006
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5. PAROXYSMAL TACHYCARDIA CAUSED BY PENTAMETHYLENE-TETRAZOL
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6. In vitro and in vivo antibacterial activity of T-1982, a new semisynthetic cephamycin antibiotic.
The activities of T-1982 (sodium 7 beta-[(2R, 3S)-2-(4-ethyl-2, 3-dioxo-1-piperazine-carboxamido)-3-hydroxybutanamido]-7 alpha-methoxy-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylate) against various gram-positive and gram-negative bacteria were compare with those of cefmetazole, cefoxitin, cefazolin, and cefoperazone. T-1982 was active agai
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7. In vitro antibacterial activity of SM-1652, a new broad-spectrum cephalosporin with antipseudomonal activity.
SM-1652 (sodium 7-[D(-)-alpha-(4-hydroxy-6-methylpyridine-3-carboxamido)-alpha-(4-hydroxyphenyl)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl) thiomethyl]-3-cephem-4-carboxylate) is a new semisynthetic cephalosporin derivative with a broad spectrum of antibacterial activity. Its in vitro activity against gram-positive bacteria was comparable to that of cefazolin.
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8. Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design
HIV integrase, the enzyme that inserts the viral DNA into the host chromosome, has no mammalian counterpart, making it an attractive target for antiviral drug design. As one of the three enzymes produced by HIV, it can be expected that inhibitors of this enzyme will complement the therapeutic use of HIV protease and reverse transcriptase inhibitors. We have
The National Academy of Sciences.
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9. In vitro and in vivo antibacterial activities of T-2588, a new oral cephalosporin, compared with those of other oral beta-lactam antibiotics.
T-2588, the pivaloyloxymethyl ester of T-2525, [6R, 7R]-7-[(z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetoamido] -3- [(5-methyl-2H-tetrazol-2-yl)methyl]-3-cephem-4-carboxylic acid, is a new oral cephalosporin. T-2525 had a widely expanded antibacterial spectrum against gram-negative and gram-positive bacteria. T-2525 was more active in vitro than cefaclor, c
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10. Role of the 7 alpha-methoxy and side-chain carboxyl of moxalactam in beta-lactamase stability and antibacterial activity.
The effects of the alpha-carboxyl of the phenylmalonyl side chain and the 7 alpha-methoxy group in moxalactam (6059-S) (7 beta-[2-carboxy-2-(4-hydroxyphenyl) acetamido]-7 alpha-methoxy-3[[(1-methyl-1H-tetrazol-5-y])thio] methyl]-1-oxa-1-dethia-3-cephem-4-carboxylic acid) and in the 1-sulfur congener on the stability to beta-lactamase were investigated by spe
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11. Antibacterial Activity of a New 1-Oxa Cephalosporin Compared with That of Other β-Lactam Compounds
The in vitro activity of (6R,7R)-7-{[carboxy(4-hydroxyphenyl)acetyl]amino}-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo-[4.2.0]oct-2-ene -2-carboxylic acid was tested against isolates of gram-positive and negative bacteria and compared with those of cephalothin, cefuroxime, cefamandole, cefoxitin, cefotaxime, and carbenicil
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12. Cefamandole, a Cephalosporin Antibiotic with an Unusually Wide Spectrum of Activity
The in vitro activity of cefamandole, 7-d-mandelamido-3-(1 methyl-1H-tetrazol-5 yethiomethyl)-3-cephem-4 carboxylic acid, was investigated. The majority of streptococci and pneumococci were inhibited by 0.1 μg/ml. Activity against Staphylococcus aureus was below that of cephalothin, but most strains were inhibited by 0.4 μg/ml. Enterococci were not inhibit