Tacripirinas
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1. Efeitos pré e pós sinápticos dos inibidores da acetilcolinesterase na neurotransmissão em musculatura lisa.
Justification: The present work considers the effects of new inhibitors of acetylcholinesterase (AChE) on the reactivity and neurotransmission in rats and mice. The new anticholinesterase compounds, ITH12118 and ITH12117, have an hybrid stucture, derived from the molecule of of the anticholinesterase Tacrine and the 1,4 dihydropyridine nimodipine, a blocker
Publicado em: 2010