Surrogate Models
Mostrando 1-12 de 19 artigos, teses e dissertações.
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1. Aerothermodynamic Optimization of Aerospace Plane Airfoil Leading Edge
ABSTRACT: Aiming to mitigate the aerodynamic heating during hypersonic re-entry, the aerothermodynamic optimization of aerospace plane airfoil leading edge is conducted. Lift-to-drag ratio at landing condition is taken as a constraint to ensure the landing aerodynamic performance. First, airfoil profile is parametrically described to be more advantageous dur
J. Aerosp. Technol. Manag.. Publicado em: 02/10/2017
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2. Uncertainty analysis of the conducted interferences in a power converter
A new methodology to analyze electrical systems in the time and frequency domain containing a large number of uncertain parameters is presented. The methodology is based on screening and design of experiments to build surrogate reduced models at a well specified set of frequency values. As an example, the conducted interferences of a Power Converter with unc
J. Microw. Optoelectron. Electromagn. Appl.. Publicado em: 2013-12
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3. Síntese ótima de processos não isotérmicos de tratamento de efluentes. / Optimal synthesis of non-isothermal wastewater treatment processes.
As metodologias para a síntese de processos, baseadas em otimização de superestruturas, mostram-se mais poderosas do que as baseadas no projeto em heuríticas, já que levam em consideração as inúmeras possibilidades de construção do processo. É pratica comum a utilização de modelos simplificados (como modelos de rendimento), na representação do
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/02/2012
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4. A methodology for safety verifications and optimum design of pipelines with defects caused by corrosion / Uma metodologia para verificaÃÃo da seguranÃa e dimensionamento Ãtimo de dutos com defeitos causados por corrosÃo
O procedimento mais adequado para verificaÃÃo da seguranÃa de uma estrutura à quantificar a sua probabilidade de falha. A determinaÃÃo deste valor pode ser feita utilizando o mÃtodo de confiabilidade de primeira ordem (FORM), que recai em um problema de otimizaÃÃo para resolver o problema de confiabilidade estrutural. Outra alternativa à aplicar o
Publicado em: 2009
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5. A study on modeling error estimates in heterogeneous materials structures. / Um estudo sobre estimativas de erro de modelagem em estruturas de materiais heterogêneos.
This work presents a study on modeling error estimates in linear elastic structures of heterogeneous materials. The employed formulation is based on a theory of a posteriori estimation of modeling errors and uses the Finite Element Method as numerical tool. The evaluated modeling errors consist of global errors based on energy norm and local errors in quanti
Publicado em: 2008
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6. Validação e comparação de testes laboratoriais simples como preditores de fibrose hepática em portadores de hepatite C crônica
Background: hepatitis C virus (HCV) chronic infection is a relevant cause of progressive liver disease, leading to cirrhosis worldwide. Liver biopsy is the gold standard to assess hepatic fibrosis but non-invasive fibrosis markers are needed. The aspartate aminotransferase to platelet ratio index (APRI) have demonstrated good accuracy to predict significant
Publicado em: 2007
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7. Diversidade beta no interflúvio Purus- Madeira : determinantes da estrutura das comunidades de Marantaceae, Araceae e Pteridófitas ao longo da BR 319, Amazonas, Brasil
Knowledge of the distribution of species along environmental and spatial gradients is very important for the development of wise conservation policies. It is known that environmental heterogeneity is a key factor on the determination of a natural community s structure. Many studies suggest the existence of surrogate groups, i.e. groups that indicate more gen
Publicado em: 2006
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8. Regulamentação do registro de agrotoxicos : abordagem da avaliação da exposição e do risco toxicologico ocupacional
The exposure assessment is part of the assessment process of health risk for the regulation of pesticides products in many countries. The toxicological evaluation risk of agricultural workers exposed to pesticides during its use is done through 3 stages (tier approach) proposed by the OECD. It is through this evaluation that the security of the product is ve
Publicado em: 2002
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9. Comparison between surrogate indexes of insulin sensitivity/resistance and hyperinsulinemic euglycemic clamp estimates in rats
Assessing insulin resistance in rodent models gives insight into mechanisms that cause type 2 diabetes and the metabolic syndrome. The hyperinsulinemic euglycemic glucose clamp, the reference standard for measuring insulin sensitivity in humans and animals, is labor intensive and technically demanding. A number of simple surrogate indexes of insulin sensitiv
American Physiological Society.
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10. Synergistic In Vitro Interactions between Alpha Interferon and Ribavirin against Bovine Viral Diarrhea Virus and Yellow Fever Virus as Surrogate Models of Hepatitis C Virus Replication
Monotherapy of hepatitis C virus infection with either alpha interferon or ribavirin alone is rather ineffective, while the use of the two antivirals together is much more efficacious. In vitro drug-drug combination analysis utilizing related members of the family Flaviviridae, bovine viral diarrhea virus and yellow fever virus, revealed significant direct s
American Society for Microbiology.
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11. Calcification in atherosclerosis: Bone biology and chronic inflammation at the arterial crossroads
Dystrophic or ectopic mineral deposition occurs in many pathologic conditions, including atherosclerosis. Calcium mineral deposits that frequently accompany atherosclerosis are readily quantifiable radiographically, serve as a surrogate marker for the disease, and predict a higher risk of myocardial infarction and death. Accelerating research interest has be
National Academy of Sciences.
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12. Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy
Currently no definitive biomarker of Alzheimer's disease (AD) is available, and this impedes both clinical diagnosis in humans and drug discovery in transgenic animal models. Proton magnetic resonance spectroscopy (1H MRS) provides a noninvasive way to investigate in vivo neurochemical abnormalities. Each observable metabolite can potentially provide informa
National Academy of Sciences.