Spontaneously Hypertensive Rats
Mostrando 1-12 de 202 artigos, teses e dissertações.
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1. Are Wistar Rats the Most Suitable Normotensive Controls for Spontaneously Hypertensive Rats to Assess Blood Pressure and Cardiac Structure and Function?
International Journal of Cardiovascular Sciences. Publicado em: 2022
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2. Losartan improves alveolar bone dynamics in normotensive rats but not in hypertensive rats
Abstract Hypertension is one of the main causes of premature death in the world; also, it is associated with several bone alterations. Preclinical studies have demonstrated delayed alveolar bone healing in hypertensive rats. However, losartan has been favorable for consolidation of bone grafts and reduction in active periodontitis. Therefore, losartan is sug
J. Appl. Oral Sci.. Publicado em: 07/10/2019
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3. Essential oil of the leaves of Eugenia sulcata preserve myocardial contractility and does not present immunotoxicity
The essential oil of the leaves of Eugenia sulcata, in the Myrtaceae family, has a demonstrated antihypertensive effect, but its effects on heart muscle and its toxicity have not yet been elucidated. Little chemical or biological data are available for E. sulcata, whether emphasizing the beneficial effects or the pharmacological security of this species. Thi
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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4. Effects of concurrent training associated with N-acetylcysteine on bone density of spontaneously hypertensive rats
Abstract Aim: The present study aimed to analyze the effects of N-acetylcysteine supplementation associated with concurrent training on the bone mineral density of spontaneously hypertensive elderly rats. Methods: For the present study, 28 male spontaneously hypertensive rats, six months old, were distributed in the following groups: control (C, n=7); co
Motriz: rev. educ. fis.. Publicado em: 29/07/2019
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5. LOW-INTENSITY ENDURANCE TRAINING AND RIGHT VENTRICULAR MYOCYTES OF HYPERTENSIVE RATS
RESUMO Introdução As adaptações estruturais e mecânicas de miócitos do ventrículo direito (VD) em resposta à hipertensão associada ao treinamento aeróbio de baixa intensidade (TABI) não foram estudadas em modelos experimentais de ratos. Objetivo Determinar os efeitos do TABI sobre as propriedades estruturais e mecânicas de miócitos do VD em
Rev Bras Med Esporte. Publicado em: 01/07/2019
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6. Pharmacological modulation of b-adrenoceptors as a new cardioprotective strategy for therapy of myocardial dysfunction induced by ischemia and reperfusion
Abstract Purpose: To evaluate the cardioprotective response of the pharmacological modulation of β-adrenergic receptors (β-AR) in animal model of cardiac ischemia and reperfusion (CIR), in spontaneously hypertensive (SHR) and normotensive (NWR) rats. Methods: CIR was induced by the occlusion of left anterior descendent coronary artery (10 min) and reper
Acta Cir. Bras.. Publicado em: 03/06/2019
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7. Moderate-intensity exercise allows enhanced protection against oxidative stress-induced cardiac dysfunction in spontaneously hypertensive rats
The progression of myocardial injury secondary to hypertension is a complex process related to a series of physiological and molecular factors including oxidative stress. This study aimed to investigate whether moderate-intensity exercise (MIE) could improve cardiac function and oxidative stress in spontaneously hypertensive rats (SHRs). Eight-week-old male
Braz J Med Biol Res. Publicado em: 16/05/2019
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8. Thermoregulation in Hypertensive Rats during Exercise: Effects of Physical Training
Resumo Fundamento: Ratos espontaneamente hipertensos (SHR) apresentam déficits no balanço térmico durante o exercício físico. Objetivo: Avaliar os efeitos do treinamento físico de baixa intensidade sobre o balanço térmico de ratos hipertensos submetidos a um protocolo de exercício físico agudo. Métodos: Ratos machos Wistar e SHR, com 16 semanas
Arq. Bras. Cardiol.. Publicado em: 14/03/2019
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9. Effects of Chronic Exposure to Mercury on Angiotensin-Converting Enzyme Activity and Oxidative Stress in Normotensive and Hypertensive Rats
Resumo Fundamento: Os efeitos deletérios do mercúrio estão associados ao risco cardiovascular aumentado. Objetivo: Determinar se a exposição crônica ao mercúrio inorgânico aumenta a atividade da enzima conversora de angiotensina e sua relação com o estresse oxidativo em vários órgãos e tecidos. Métodos: Estudamos ratos Wistar e ratos esponta
Arq. Bras. Cardiol.. Publicado em: 07/01/2019
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10. Captopril alleviates hypertension-induced renal damage, inflammation, and NF-κB activation
Hypertensive renal damage generally occurs during the middle and late stages of hypertension, which is typically characterized by proteinuria and renal inflammation. Captopril, an angiotensin-converting enzyme (ACE) inhibitor, has been widely used for therapy of arterial hypertension and cardiovascular diseases. However, the protective effects of captopril o
Braz J Med Biol Res. Publicado em: 03/09/2018
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11. Aerobic Swim Training Restores Aortic Endothelial Function by Decreasing Superoxide Levels in Spontaneously Hypertensive Rats
OBJECTIVE: We aimed to determine whether aerobic training decreases superoxide levels, increases nitric oxide levels, and improves endothelium-dependent vasodilation in the aortas of spontaneously hypertensive rats. METHODS: Spontaneously hypertensive rats (SHR) and Wistar Kyoto rats (WKY) were distributed into 2 groups: sedentary (SHRsd and WKYsd, n=10 ea
Clinics. Publicado em: 2017-05
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12. Swimming training prevents coronary endothelial dysfunction in ovariectomized spontaneously hypertensive rats
Estrogen deficiency and hypertension are considered major risk factors for the development of coronary heart disease. On the other hand, exercise training is considered an effective form to prevent and treat cardiovascular diseases. However, the effects of swimming training (SW) on coronary vascular reactivity in female ovariectomized hypertensive rats are n
Braz J Med Biol Res. Publicado em: 16/01/2017