Spontaneous Emulsification
Mostrando 1-11 de 11 artigos, teses e dissertações.
-
1. Hyaluronic acid-coated nanoemulsions loaded with a hydrophobic ion pair of all-trans retinoic acid for improving the anticancer activity
All-trans retinoic acid (ATRA) has been studied for the treatment of cancer, including leukemia and breast cancer. This work aims to develop nanoemulsions (NE) loaded with a hydrophobic ion pair (HIP) of all-trans retinoic acid (ATRA) and a lipophilic amine, stearylamine (SA), and coated with hyaluronic acid (HA) to enhance anticancer activity and reducing t
Braz. J. Pharm. Sci.. Publicado em: 08/04/2019
-
2. Physicochemical properties of lecithin-based nanoemulsions obtained by spontaneous emulsification or high-pressure homogenization
Nanoemulsions composed of a medium-chain triglyceride oil core stabilized by rapeseed or sunflower lecithins were prepared by spontaneous emulsification and high-pressure homogenization. These nanoemulsions are compared with formulations stabilized by egg lecithin. Nanoemulsions obtained by high-pressure homogenization display larger droplet size (230 to 440
Quím. Nova. Publicado em: 2014
-
3. Errata: Physicochemical properties of lecithin-based nanoemulsions obtained by spontaneous emulsification or high-pressure homogenization
Quím. Nova. Publicado em: 2014
-
4. Preparação e caracterização de nanoemulsões contendo oligonucleotídeos antisense através da técnica de emulsificação espontânea / Preparation and characterization of nanoemulsions containing antisense oligonucleotides by spontaneous emulsifications procedure
Recentemente, nanoemulsões preparadas pela técnica de microfluidização foram propostas como um sistema de liberação de oligonucleotídeos antisense (ON) por Teixeira et al. [J. contr. rel., 70:243-255, 2001]. O objetivo do presente trabalho foi preparar e caracterizar nanoemulsões através de uma técnica alternativa, a emulsificação espontânea, vi
Publicado em: 2010
-
5. Desenvolvimento de sistemas micro e nanoestruturados de quitosana/MDI para aplicações cosméticas
O presente trabalho visou o estudo e desenvolvimento de um sistema micro e nanoestruturado de quitosana reticulada por diisocianato, pela técnica de policondensação interfacial combinada com emulsificação espontânea, para encapsulação de benzofenona-3 (BZ-3), um filtro solar químico. Foi elaborado primeiramente um planejamento experimental de 23 par
Publicado em: 2009
-
6. Adsorção de oligonucleotídeos em nanoemulsões obtidas por emulsificação espontânea
This paper describes the adsorption of an oligothymidylate (pdT16) on nanoemulsions obtained by spontaneous emulsification procedures. Formulations were composed by medium chain triglycerides, egg lecithin, glycerol, water (NE) and stearylamine (NE SA). After optimization of operating conditions, the mean droplet size was smaller than 255 nm. Adsorption isot
Química Nova. Publicado em: 2007-08
-
7. Micro-emultocrit technique: A valuable tool for determination of critical HLB value of emulsions
The aim of this work was to develop a methodology for rapid determination of the critical hydrophilic-lipophilic balance (HLB) value of lipophilic fractions of emulsions. The emulsions were prepared by the spontaneous emulsification process with HLB value from 4.3 to 16.7. The preparations were stored at 2 different temperatures (25°C and 4°C) and their ph
Springer-Verlag.
-
8. Role of adherence in growth of Acinetobacter calcoaceticus RAG-1 on hexadecane.
The high affinity of Acinetobacter calcoaceticus RAG-1 for liquid hydrocarbons permitted the isolation of a spontaneous nonadherent mutant, MR-481. Strain MR-481 exhibited no significant affinity for three test hydrocarbons, yet resembled the wild type in many properties, including production of the extracellular emulsifying agent emulsan. To study the role
-
9. Formulation development and optimization using nanoemulsion technique: A technical note
Ramipril nanoemulsion formulations were successfully prepared by the spontaneous emulsification method (titration method). Sefsol 218 was selected as the oil phase for the development of the formulation on the basis of the solubility studies. The differences in the droplet size between the formulations selected from the phase diagram was not statistically si
Springer-Verlag.
-
10. Lecithin organogels as a potential phospholipid-structured system for topical drug delivery: A review
The purpose of this review is to give an insight into the considerable potential of lecithin organogels (LOs) in the applications meant for topical drug delivery. LOs are clear, thermodynamically stable, viscoelastic, and biocompatible jelly-like phases, chiefly composed of hydrated phospholipids and appropriate organic liquid. These systems are currently of
Springer-Verlag.
-
11. Nanoemulsions as vehicles for transdermal delivery of aceclofenac
The aim of the present study was to investigate the potential of a nanoemulsion formulation for transdermal delivery of aceclofenac. Various oil-in-water nanoemulsions were prepared by the spontaneous emulsification method. The nanoemulsion area was identified by constructing pseudoternary phase diagrams. The prepared nanoemulsions were subjected to differen
Springer-Verlag.