Soft Gelatin Capsules
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. Desenvolvimento de cÃpsula gelatinosa mole de Ã-Lapachona para terapias antineoplÃsticas em humanos
The β-Lapachone (C15H14O3, MM 242,3), designated chemically as (3,4-dihydro-2,2- dimethyl-2H-naphtol[1,2-b]pyran-5,6-dione), is an o-naphtoquinone isolated from the lapacho tree (Tabebuia avellandae), of the family Bignonaceae. Recent researches have been demonstrating its excellent antineoplasic potential, acting against several types of human cancer b
Publicado em: 2004
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2. Safety and Pharmacokinetics of Amprenavir (141W94), a Human Immunodeficiency Virus (HIV) Type 1 Protease Inhibitor, following Oral Administration of Single Doses to HIV-Infected Adults
We conducted a double-blind, placebo-controlled, parallel, dose-escalation trial to evaluate the pharmacokinetics and safety of single, oral doses of amprenavir (141W94; formerly VX-478), a potent inhibitor of human immunodeficiency virus (HIV) type 1 protease, administered as hard gelatin capsules in 12 HIV-infected subjects. The doses of amprenavir evaluat
American Society for Microbiology.
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3. Single-Dose Safety and Pharmacokinetics of Amprenavir (141W94), a Human Immunodeficiency Virus Type 1 (HIV-1) Protease Inhibitor, in HIV-Infected Children
A phase I, open-label, dose-escalating trial was conducted to evaluate the safety, tolerability, and pharmacokinetics of single, oral doses of amprenavir (141W94), a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) protease, in 20 HIV-infected children 4 to 12 years of age. The doses of amprenavir evaluated, 5, 10, 15, and 20 mg/kg of body wei
American Society for Microbiology.