Sickle Cell Anemia Diagnosis
Mostrando 1-12 de 26 artigos, teses e dissertações.
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1. HemoTypeSC point-of-care testing shows high sensitivity with alkaline cellulose acetate hemoglobin electrophoresis for screening hemoglobin SS and SC genotypes
ABSTRACT Introduction: By providing timely actionable results for prompt management, point-of-care testing (POCT) kits have revolutionised medical care for various diseases, ranging from infectious diseases like malaria to genetic disorders, such as sickle cell disease (SCD). They are, however, underutilised in the diagnosis of SCD in developing countries,
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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2. Review of a three-year study on the dental care of onco-hematological pediatric patients
The aim of this study was to provide an updated review of dental procedures undertaken at the dental unit of the Onco-hematology service of the Instituto da Criança at the Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (ICr/HC-FMUSP). We retrospectively reviewed 565 of 1902 medical and dental records of patients diagnosed with onc
Clinics. Publicado em: 03/12/2018
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3. Mortality by sickle cell disease in Brazil
Abstract This work aimed to characterize mortality by sickle cell disease in Brazil. The MEDLINE electronic database was searched using the terms ‘mortality' and ‘sickle cell disease' and ‘Brazil' for articles published in the last five years aiming to provide a current analysis of the subject in question. Eight studies on mortality by sickle cell dise
Rev. Bras. Hematol. Hemoter.. Publicado em: 2017-03
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4. Hemoglobin A2 values in sickle cell disease patients quantified by high performance liquid chromatography and the influence of alpha thalassemia
BACKGROUND: In sickle cell disease, the quantification of Hb A2 is important for the differential diagnosis between sickle cell anemia (Hb SS) and Hb S/ß0-thalassemia.OBJECTIVE: To determine Hb A2 levels as quantified by high performance liquid chromatography in patients with sickle cell anemia (Hb SS) and with the SC hemoglobinopathy, with or without conco
Rev. Bras. Hematol. Hemoter.. Publicado em: 2015-10
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5. Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia
OBJECTIVE: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients. METHODS: A cross-sectional study was performed of 30 patients with molecular diagnosis of sickle cell anemia. Patients were stratified into two groups, according to t
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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6. Prevalence of glutathione S-transferase gene deletions and their effect on sickle cell patients
BACKGROUND: Glutathione S-transferase gene deletions are known detoxification agents and cause oxidative damage. Due to the different pathophysiology of anemia in thalassemia and sickle cell disease, there are significant differences in the pathophysiology of iron overload and iron-related complications in these disorders. OBJECTIVE: The aim of this study wa
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2012
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7. The burden and quality of life of caregivers of sickle cell anemia patients taking hydroxyurea versus those not taking hydroxyurea
OBJECTIVE: To assess the burden and quality of life of caregivers of patients with sickle cell anemia taking hydroxyurea versus those of patients not taking hydroxyurea. METHODS: A cross-sectional study was performed of caregivers of outpatients with sickle cell anemia in two public hospitals in Campo Grande, MS, from January through June 2010. The World Hea
Rev. Bras. Hematol. Hemoter.. Publicado em: 2012
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8. Correlation of low levels of nitrite and high levels of fetal hemoglobin in patients with sickle cell disease at baseline
BACKGROUND: Sickle cell disease is a hemoglobinopathy characterized by hemolytic anemia, increased susceptibility to infections and recurrent vaso-occlusive crises that reduces the quality of life of sufferers. OBJECTIVE: To evaluate the correlation of the levels of lactate dehydrogenase, malonaldehyde and nitrite to fetal hemoglobin in patients with sickle
Rev. Bras. Hematol. Hemoter.. Publicado em: 2012
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9. A model of genetic guidance for hemoglobinopathy patients and laboratory diagnosis of family members as educational and preventive measures
BACKGROUND: The high frequency of hemoglobinopathies in Brazil constitutes a public health problem and thus educational and preventive measures are necessary to reduce the incidence. Genetic guidance, a modality of genetic counseling, and family screening are measures that can assist in reproductive decisions and mitigate clinical, psychological and social p
Rev. Bras. Hematol. Hemoter.. Publicado em: 2012
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10. Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality. These benefits have resulted in the widespread use of newborn screening education programs. In Brazil, the National Neonatal Screening Program established by decree 822
Revista Brasileira de Hematologia e Hemoterapia. Publicado em: 2011-02
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11. Avaliação das células endoteliais circulantes na trombose venosa profunda : pacientes e modelo animal / Evaluation of the circulating endothelial cell in deep venous thrombosis : patients and animal model
Endothelial cells participate in hemostasia and have pro and anti thrombotic effects which can be stimulated by an endothelial lesion. The presence of endothelial cells in circulation can be considered a novel marker of vascular integrity, as described in several pathologies, such as: cardiovascular disease, infectious disease, immune diseases, transplants
Publicado em: 2010
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12. Anemia falciforme e triagem neonatal : o significado da prevenção para as mulheres cuidadoras
Newborn screening programs were created by the end of the 1950s and since then were widespread through several countries as an important tool for controlling morbidity and mortality caused by diagnosable and treatable diseases. Women play a central role in newborn screening, since care and adhesion to the child treatment depends on them. The goal of this the
Publicado em: 2009