Sex Reversal
Mostrando 1-12 de 65 artigos, teses e dissertações.
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1. Clinical and molecular characterization of a Brazilian cohort of campomelic dysplasia patients, and identification of seven new SOX9 mutations
Campomelic dysplasia (CD) is an autosomal, dominantly inherited, skeletal abnormality belonging to the subgroup of bent bone dysplasias. In addition to bowed lower limbs, CD typically includes the following: disproportionate short stature, flat face, micrognathia, cleft palate, bell-shaped thorax, and club feet. Up to three quarters of 46, XY individuals may
Genet. Mol. Biol.. Publicado em: 2015-03
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2. Growth of Nile tilapia post-larvae from broodstock fed diet with different levels of digestible protein and digestible energy
This study was carried out to evaluate the influence of different levels of digestible energy and digestible protein in diets of Nile tilapia (Oreochromis niloticus) broodstock on offspring growth during sex reversal stage. A total of 2,700 post-larvae (8.2±0.001 mg) derived from breeders fed nine diets with distinct levels of digestible protein (28, 34 and
R. Bras. Zootec.. Publicado em: 2013-08
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3. Perfil dos esteroides gonadais e expressão dos hormônios folículo estimulante (FSH) e luteinizante (LH) durante a inversão sexual de Epinephelus marginatus (Teleostei: Serranidae), hermafrodita protogínico, utilizando-se inibidor de aromatase / Gonadal steroids profile and expression of follicle-stimulating (FSH) and luteinizing (LH) hormones during the sex reversal of Epinephelus marginatus (Teleostei: Serranidae) hermaphroditic protogynous, using aromatase inhibitor
A plasticidade do desenvolvimento gonadal em peixes, que contrasta com os padrões mais estáveis encontrados nos demais vertebrados, deu origem a várias questões intrigantes relativas tanto ao seu significado adaptativo quanto aos fatores genéticos e fisiológicos que modulam o processo. A inversão do sexo em peixes hermafroditas seqüenciais (protândr
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/08/2012
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4. Leprosy reactions: coinfections as a possible risk factor
OBJECTIVE: This study aimed to determine the frequency of coinfections in leprosy patients and whether there is a relationship between the presence of coinfections and the development of leprosy reactional episodes. METHOD: A cross-sectional study based on an analysis of the medical records of the patients who were treated at the Leprosy Clinics of the Ribei
Clinics. Publicado em: 2012-10
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5. The novel p.E89K mutation in the SRY gene inhibits DNA binding and causes the 46,XY disorder of sex development
Male sex determination in humans is controlled by the SRY gene, which encodes a transcriptional regulator containing a conserved high mobility group box domain (HMG-box) required for DNA binding. Mutations in the SRY HMG-box affect protein function, causing sex reversal phenotypes. In the present study, we describe a 19-year-old female presenting 46,XY karyo
Brazilian Journal of Medical and Biological Research. Publicado em: 2011-04
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6. MananoligossacarÃdeo durante a reversÃo sexual de tilÃpia do nilo / Mannanoligosaccharide during the sexual reversion for nile tilapia
This present study aimed to evaluate the use of prebiotic mannanoligosaccharide (Bio-MosÂ) during the sexual reversion to larvae of Nile tilapia. The study was realized in the Laboratory of Aquaculture of the Western Parana State University (Unioeste). Onethousand nd eighty larvae of Nile tilapia with three days old and initial average weight of 10.9 Â 1.2
Publicado em: 2009
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7. ReversÃo sexual da tilÃpia do Nilo, Oreochromis niloticus (vr. Chitralada), em diferentes salinidades na presenÃa da microalgas Spirulina platensis (Cyanophyta) / Sex reversal of Nile tilapia, Oreochromis niloticus (vr. Chitralada) at different salinities in the presence of microalgae Spirulina platensis (Cyanophyta)
A larva da tilÃpia do Nilo, Oreochromis niloticus, durante os primeiros dias de vida, supre suas necessidades nutricionais com a reserva vitelÃnica, pois nem a cavidade bucal encontra-se aberta nem o trato intestinal completamente formado. ApÃs o consumo do vitelo, o peixe jà à uma pÃs-larva e sua alimentaÃÃo passa a ser exÃgena e à composta, princ
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/06/2008
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8. Expression of IGF-II, IGF-IR, SF-1 and DAX-1 genes in pediatric and adult adrenocortical tumors / Expressão dos genes IGF-II, IGF-IR, SF-1 e DAX-1 em tumores adrenocorticais de crianças e adultos
Introduction: The molecular pathogenesis of adrenocortical tumors is heterogeneous and incompletely understood. Insulin-like growth factor II (IGF-II) overexpression has been demonstrated in adult adrenocortical carcinomas. IGF-II exerts its mitogenic effects through interaction with IGF-I receptor (IGF-IR). In addition, steroidogenic factor 1 gene (SF-1) an
Publicado em: 2008
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9. Morpho-functional characteristics of sex reversal in Synbranchidae (Teleostei: Synbranchiformes) / Perfil morfo-funcional da inversão de sexo em Synbranchidae (Teleostei: Synbranchiformes)
Teleost fishes exhibit several sexual patterns during their ontogeny, in which the gonads change into functional ovaries or testes. In distinct Orders, both gonochoristic and hermaphrodite species, simultaneous as well as sequential or consecutive, can be found. In sequential hermaphroditism (protandrous or protogynous), sex change in adult individuais invol
Publicado em: 2006
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10. Mutations in the SRY, DAX1, SF1 and WNT4 genes in Brazilian sex-reversed patients
In most mammals, male development is triggered by the transient expression of the SRY gene, which initiates a cascade of gene interactions ultimately leading to the formation of a testis from the indifferent fetal gonad. Mutation studies have identified several genes essential for early gonadal development. We report here a molecular study of the SRY, DAX1,
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-01
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11. Evidence to exclude SOX9 as a candidate gene for XY sex reversal without skeletal malformation.
The skeletal malformation syndrome campomelic dysplasia (CMD1) is caused by mutations within the SOX9 gene or chromosomal rearrangement breakpoints outside SOX9. Approximately three quarters of cases of CMD1 in XY subjects show complete or partial sex reversal. As some mutations cause CMD1 alone and others cause CMD1 and sex reversal, it is conceivable that
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12. Mutation analysis of the 2 kb 5' to SRY in XY females and XY intersex subjects.
Mutations in the Y linked testis determining gene SRY cause 46,XY sex reversal. However, only about 15% of cases of 46,XY sex reversal are accounted for by mutations in SRY. In this study we have investigated the possibility that mutations affecting the expression of SRY might cause some of the cases of sex reversal in which the coding sequence of SRY is nor