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Mostrando 1-2 de 2 artigos, teses e dissertações.
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1. Participação do sistema da orexina na sensibilização comportamental ao efeito estimulante do etanol em camundongos machos / Role of orexin system in ethanol-induced behavioral sensitization in male mice
Orexins are two neuropeptides, orexin-A and orexin-B, derived from the same precursor gene (pre-pro-orexin) produced by a few thousand neurons located in the perifornical area of the lateral hypothalamus. Despite having a restricted production, orexinergic neurons project widely to brain structures that regulate a number of endocrine and homeostatic function
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/03/2011
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2. Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness
Recent data from transgenic mice suggest that orexin plays an important role in the ventilatory response to CO2 during wakefulness. We hypothesized that orexin receptor-1 (OX1R) in the retrotrapezoid nucleus (RTN) contributes to chemoreception. In unanaesthetized rats, we measured ventilation using a whole-body plethysmograph, together with EEG and EMG. We d
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